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lorazepam and Amnesia, Anterograde

lorazepam has been researched along with Amnesia, Anterograde in 2 studies

Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.

Amnesia, Anterograde: Loss of the ability to form new memories beyond a certain point in time. This condition may be organic or psychogenic in origin. Organically induced anterograde amnesia may follow CRANIOCEREBRAL TRAUMA; SEIZURES; ANOXIA; and other conditions which adversely affect neural structures associated with memory formation (e.g., the HIPPOCAMPUS; FORNIX (BRAIN); MAMMILLARY BODIES; and ANTERIOR THALAMIC NUCLEI). (From Memory 1997 Jan-Mar;5(1-2):49-71)

Research Excerpts

ExcerptRelevanceReference
" Whereas vigilance, psychomotor performance and free recall were significantly impaired by lorazepam, neither dosage of etifoxine (50 and 100 mg) produced such effects."2.70A double blind parallel group placebo controlled comparison of sedative and mnesic effects of etifoxine and lorazepam in healthy subjects [corrected]. ( Alquier, C; Blin, O; Bruguerolle, B; Guet, F; Le Guern, ME; Micallef, J; Soubrouillard, C, 2001)
"The parameter values derived from PK/PD modelling, and especially the EC50 values, may provide sensitive indices that can be used, rather than the raw data derived from pharmacodynamic measurements, to compare CNS effects of benzodiazepines."2.69Pharmacokinetic-pharmacodynamic analysis of mnesic effects of lorazepam in healthy volunteers. ( Blin, O; Bruguerolle, B; Callamand, S; Durand, A; Gayraud, D; Habib, M; Jacquet, A; Jouve, E; Pisano, P, 1999)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Blin, O2
Jacquet, A1
Callamand, S1
Jouve, E1
Habib, M1
Gayraud, D1
Durand, A1
Bruguerolle, B2
Pisano, P1
Micallef, J1
Soubrouillard, C1
Guet, F1
Le Guern, ME1
Alquier, C1

Trials

2 trials available for lorazepam and Amnesia, Anterograde

ArticleYear
Pharmacokinetic-pharmacodynamic analysis of mnesic effects of lorazepam in healthy volunteers.
    British journal of clinical pharmacology, 1999, Volume: 48, Issue:4

    Topics: Amnesia, Anterograde; Anti-Anxiety Agents; Cross-Over Studies; Double-Blind Method; Humans; Lorazepa

1999
A double blind parallel group placebo controlled comparison of sedative and mnesic effects of etifoxine and lorazepam in healthy subjects [corrected].
    Fundamental & clinical pharmacology, 2001, Volume: 15, Issue:3

    Topics: Adolescent; Adult; Affect; Amnesia, Anterograde; Attention; Double-Blind Method; Female; Humans; Hyp

2001