lorazepam has been researched along with Alcohol Abuse in 63 studies
Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with intravenous lorazepam is associated with a significant reduction in the risk of recurrent seizures related to alcohol." | 9.09 | Lorazepam for the prevention of recurrent seizures related to alcohol. ( D'Onofrio, G; Fish, SS; Freedland, ES; Rathlev, NK; Ulrich, AS, 1999) |
| "To perform a randomized evaluation of lorazepam and ethanol/lorazepam to evaluate the safety and efficacy of these 2 strategies for preventing alcohol withdrawal syndrome in patients with acute coronary syndromes." | 5.17 | Alcohol withdrawal prevention: a randomized evaluation of lorazepam and ethanol--a pilot study. ( Bride, W; Fullwood, JE; Granger, BB; Granger, CB; Mostaghimi, Z; Washam, JB; Zhao, Y, 2013) |
| " The primary objective of this study was to compare the efficacy of gabapentin to lorazepam in alleviating sleep disturbances and daytime sleepiness during an episode of alcohol withdrawal." | 5.12 | Self-reported sleep, sleepiness, and repeated alcohol withdrawals: a randomized, double blind, controlled comparison of lorazepam vs gabapentin. ( Boyle, E; Malcolm, R; Myrick, LH; Randall, PK; Veatch, LM, 2007) |
| "Treatment with intravenous lorazepam is associated with a significant reduction in the risk of recurrent seizures related to alcohol." | 5.09 | Lorazepam for the prevention of recurrent seizures related to alcohol. ( D'Onofrio, G; Fish, SS; Freedland, ES; Rathlev, NK; Ulrich, AS, 1999) |
| "The transient amnesia produced by lorazepam has been suggested to have much in common with the permanent amnesia associated with organic brain damage." | 5.07 | A comparison of the amnesic effects of lorazepam in alcoholics and non-alcoholics. ( Hennessy, MJ; Kirkby, KC; Mallick, JL; Martin, F; Philp, M, 1993) |
| "While some case reports indicate that high doses of propylene glycol (PG) may result in metabolic acidosis, there has been no large-scale study that evaluated the risk of metabolic acidosis in patients receiving PG-containing benzodiazepines for acute alcohol withdrawal." | 3.88 | Assessing Propylene Glycol Toxicity in Alcohol Withdrawal Patients Receiving Intravenous Benzodiazepines: A One-Compartment Pharmacokinetic Model. ( Bodreau, C; Elbarbry, F; Farthing, K; Jahn, A, 2018) |
| " The authors present three patients with alcoholism in whom diagnosis of panic was facilitated by intravenous lactate infusion, and whose symptoms were alleviated by clonazepam." | 3.68 | The diagnosis and treatment of panic disorder in alcoholics: three cases. ( Baron, DH; Ciraulo, DA; Sands, BF; Shader, RI, 1990) |
| " Non-BZD adverse events warrant further investigation." | 3.01 | Beyond benzodiazepines: a meta-analysis and narrative synthesis of the efficacy and safety of alternative options for alcohol withdrawal syndrome management. ( Fluyau, D; Kailasam, VK; Pierre, CG, 2023) |
| "Anxiety is common among persons with alcohol use disorder during early abstinence from alcohol." | 2.82 | Coadministration of disulfiram and lorazepam in the treatment of alcohol dependence and co-occurring anxiety disorder: an open-label pilot study. ( Bhatt, S; Bogenschutz, MP; Bohan, J; Foster, B; Romo, P; Tonigan, JS; Wilcox, CE, 2016) |
| "Lorazepam treated group showed a significant difference in the rate of improvement over 48 h compared to chlordiazepoxide group (70." | 2.78 | A double blind randomised comparison of chlordiazepoxide and lorazepam in alcohol withdrawal. ( Mohandas, E; Rajmohan, V; Sushil, K, 2013) |
| "One hundred consecutive consenting male inpatients in a state of moderately severe, uncomplicated alcohol withdrawal at screening were randomized to receive either lorazepam (8 mg/day) or chlordiazepoxide (80 mg/day) with dosing down-titrated to zero in a fixed-dose schedule across 8 treatment days." | 2.74 | A randomized, double-blind comparison of lorazepam and chlordiazepoxide in patients with uncomplicated alcohol withdrawal. ( Andrade, C; Kumar, CN; Murthy, P, 2009) |
| "Lormetazepam or placebo were randomly assigned and given in a double-blind fashion." | 2.70 | Fast withdrawal from benzodiazepines in geriatric inpatients: a randomised double-blind, placebo-controlled trial. ( Afschrift, M; Mariman, A; Petrovic, M; Pevernagie, D; Van Maele, G, 2002) |
| "Carbamazepine and lorazepam were equally effective at decreasing the symptoms of alcohol withdrawal." | 2.70 | The effects of carbamazepine and lorazepam on single versus multiple previous alcohol withdrawals in an outpatient randomized trial. ( Anton, RF; Ballenger, JC; Malcolm, R; Myrick, H; Roberts, J; Wang, W, 2002) |
| " This was also reflected in the spectral analyzed EEG, which showed, after one single dosage of both drugs, a typical anxiolytic profile which was more pronounced after lopirazepam than prazepam, while after the chronic administration (12 h after the evening medication) only prazepam showed an anxiolytic profile." | 2.65 | Clinical symptomatology and computer analyzed EEG before, during and after anxiolytic therapy of alcohol withdrawal patients. ( Grünberger, J; Karobath, M; Mader, R; Saletu, B; Saletu, M, 1983) |
| " Guidelines recommend dosing based on objectively measured symptoms (symptom-triggered therapy) rather than fixed dose regimens." | 2.61 | Symptom-Triggered Therapy for Alcohol Withdrawal Syndrome: a Systematic Review and Meta-analysis of Randomized Controlled Trials. ( Gunderson, CG; Holleck, JL; Merchant, N, 2019) |
| "The threshold for seizures is lowered by tramadol." | 2.41 | Lethal combination of tramadol and multiple drugs affecting serotonin. ( Levine, BS; Pestaner, JP; Ripple, MG; Smialek, JE, 2000) |
| "The few in-ED seizures occurred before medication administration." | 1.56 | Lorazepam Versus Diazepam in the Management of Emergency Department Patients With Alcohol Withdrawal. ( Barbic, D; Chiu, I; Duley, S; Grafstein, E; Grunau, B; Innes, G; Kestler, A; Lane, DJ; Miles, I; Moe, J; Nolan, S; Scheuermeyer, FX; Slaunwhite, A; Sljivic, I; Ti, L; Yan, A, 2020) |
| "Phenobarbital has been shown to be an effective adjunctive therapy for AWS, reducing benzodiazepine use, in the emergency department." | 1.56 | Phenobarbital and symptom-triggered lorazepam versus lorazepam alone for severe alcohol withdrawal in the intensive care unit. ( Lam, SW; Nguyen, TA, 2020) |
| "Women and patients with an alcohol use disorder or unhealthy alcohol use, compared with men and patients with low-risk drinking or abstinence, were more likely to use a benzodiazepine; however, their LEDDs were lower and their prescription durations were shorter." | 1.51 | Benzodiazepine and unhealthy alcohol use among adult outpatients. ( Campbell, CI; Hirschtritt, ME; Kline-Simon, AH; Kroenke, K; Palzes, VA; Sterling, SA, 2019) |
| "Individuals with alcohol use disorders (AUDs) have deficits in cognitive control, but how they change with treatment is unclear." | 1.42 | Cognitive control network function in alcohol use disorder before and during treatment with lorazepam. ( Bogenschutz, MP; Cumbo, H; Dekonenko, C; Ling, J; Mayer, AR; Wilcox, CE, 2015) |
| "Subacute encephalopathy with seizures in chronic alcoholism (SESA) was first described in 1981 by Niedermeyer who reported alcoholic patients presenting with confusion, seizures and focal neurological deficits and is quite distinct from patients presenting with typical alcohol withdrawal seizures." | 1.37 | Subacute encephalopathy and seizures in alcoholics (SESA) presenting with non-convulsive status epilepticus. ( LaRoche, SM; Shivdat-Nanhoe, R, 2011) |
| "Alcohol abuse is common in patients with squamous cell cancer of the head and neck." | 1.33 | Alcohol withdrawal prophylaxis in patients undergoing surgical treatment of head and neck squamous cell carcinoma. ( Gourin, CG; Neyman, KM; Terris, DJ, 2005) |
| " Drug was most often given on a fixed dosing schedule with additional medication "as needed" (52% of the programs)." | 1.29 | Alcohol withdrawal: a nationwide survey of inpatient treatment practices. ( Friedman, LS; Mayo-Smith, MF; Saitz, R, 1995) |
| " These findings and other results of pharmacokinetic research have clinical implications in terms of dosage schedules, drug accumulation during long-term therapy, antianxiety therapy in the elderly, drug interactions, pharmacotherapy in specific disease states, and the influence of route of administration on drug action." | 1.26 | Clinical implications of benzodiazepine pharmacokinetics. ( Greenblatt, DJ; Shader, RI, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (15.87) | 18.7374 |
| 1990's | 15 (23.81) | 18.2507 |
| 2000's | 16 (25.40) | 29.6817 |
| 2010's | 17 (26.98) | 24.3611 |
| 2020's | 5 (7.94) | 2.80 |
| Authors | Studies |
|---|---|
| Gonzalez, J | 1 |
| Upadhyaya, VD | 1 |
| Manna, ZT | 1 |
| Sharma, AR | 1 |
| Christopher, J | 1 |
| Douedi, S | 1 |
| Sen, S | 1 |
| Fluyau, D | 1 |
| Kailasam, VK | 1 |
| Pierre, CG | 1 |
| Andaluz, A | 1 |
| DeMoss, D | 1 |
| Claassen, C | 1 |
| Blair, S | 1 |
| Hsu, J | 1 |
| Bakre, S | 1 |
| Khan, M | 1 |
| Atem, F | 1 |
| Rush, AJ | 1 |
| Hirschtritt, ME | 1 |
| Palzes, VA | 1 |
| Kline-Simon, AH | 1 |
| Kroenke, K | 1 |
| Campbell, CI | 1 |
| Sterling, SA | 1 |
| Scheuermeyer, FX | 1 |
| Miles, I | 1 |
| Lane, DJ | 1 |
| Grunau, B | 1 |
| Grafstein, E | 1 |
| Sljivic, I | 1 |
| Duley, S | 1 |
| Yan, A | 1 |
| Chiu, I | 1 |
| Kestler, A | 1 |
| Barbic, D | 1 |
| Moe, J | 1 |
| Slaunwhite, A | 1 |
| Nolan, S | 1 |
| Ti, L | 1 |
| Innes, G | 1 |
| Jahn, A | 1 |
| Bodreau, C | 1 |
| Farthing, K | 1 |
| Elbarbry, F | 1 |
| Holleck, JL | 1 |
| Merchant, N | 1 |
| Gunderson, CG | 1 |
| Morrison, M | 1 |
| Udeh, E | 1 |
| Burak, M | 1 |
| Nguyen, TA | 1 |
| Lam, SW | 1 |
| Fullwood, JE | 1 |
| Mostaghimi, Z | 1 |
| Granger, CB | 1 |
| Washam, JB | 1 |
| Bride, W | 1 |
| Zhao, Y | 1 |
| Granger, BB | 1 |
| Rajmohan, V | 1 |
| Sushil, K | 1 |
| Mohandas, E | 1 |
| Huang, MC | 2 |
| Chen, CH | 2 |
| Pan, CH | 1 |
| Lin, SK | 1 |
| Hoch, HJ | 1 |
| Gehring, C | 1 |
| Prakash, S | 1 |
| Mandal, P | 1 |
| Wilcox, CE | 2 |
| Mayer, AR | 1 |
| Bogenschutz, MP | 2 |
| Ling, J | 1 |
| Dekonenko, C | 1 |
| Cumbo, H | 1 |
| Bhatt, S | 1 |
| Bohan, J | 1 |
| Foster, B | 1 |
| Romo, P | 1 |
| Tonigan, JS | 1 |
| Brady, KT | 1 |
| Kumar, CN | 1 |
| Andrade, C | 1 |
| Murthy, P | 1 |
| Martinotti, G | 1 |
| di Nicola, M | 1 |
| Frustaci, A | 1 |
| Romanelli, R | 1 |
| Tedeschi, D | 1 |
| Guglielmo, R | 1 |
| Guerriero, L | 1 |
| Bruschi, A | 1 |
| De Filippis, R | 1 |
| Pozzi, G | 1 |
| Di Giannantonio, M | 1 |
| Bria, P | 1 |
| Janiri, L | 1 |
| Yan, MT | 1 |
| Chau, T | 1 |
| Cheng, CJ | 1 |
| Lin, SH | 1 |
| Fung, EC | 1 |
| Crook, MA | 1 |
| Liu, HC | 1 |
| Chen, CC | 1 |
| Ho, CC | 1 |
| Leu, SJ | 1 |
| LaRoche, SM | 1 |
| Shivdat-Nanhoe, R | 1 |
| Tuohy, KA | 1 |
| Nicholson, WJ | 1 |
| Schiffman, F | 1 |
| Devi, G | 1 |
| Neyman, KM | 1 |
| Gourin, CG | 1 |
| Terris, DJ | 1 |
| Schmidt, LG | 1 |
| Bleich, S | 1 |
| Boening, J | 1 |
| Buehringer, G | 1 |
| Kornhuber, J | 1 |
| Weijers, HG | 1 |
| Wiesbeck, GA | 1 |
| Wolfgramm, J | 1 |
| Havemann-Reinecke, U | 1 |
| Schlösser, RG | 1 |
| Gesierich, T | 1 |
| Wagner, G | 1 |
| Bolz, M | 1 |
| Gründer, G | 1 |
| Dielentheis, TF | 1 |
| Scherb, C | 1 |
| Stoeter, P | 1 |
| Malcolm, R | 4 |
| Myrick, LH | 1 |
| Veatch, LM | 1 |
| Boyle, E | 1 |
| Randall, PK | 1 |
| Han, DH | 1 |
| Lyool, IK | 1 |
| Sung, YH | 1 |
| Lee, SH | 1 |
| Renshaw, PF | 1 |
| Tsao, YT | 1 |
| Tsai, WC | 1 |
| Yang, SP | 1 |
| Saletu, M | 1 |
| Saletu, B | 1 |
| Grünberger, J | 1 |
| Mader, R | 1 |
| Karobath, M | 1 |
| Naranjo, CA | 1 |
| Sellers, EM | 1 |
| Chater, K | 1 |
| Iversen, P | 1 |
| Roach, C | 1 |
| Sykora, K | 1 |
| Kemper, N | 1 |
| Poser, W | 1 |
| Poser, S | 1 |
| Volkow, ND | 3 |
| Wang, GJ | 3 |
| Begleiter, H | 1 |
| Hitzemann, R | 3 |
| Pappas, N | 3 |
| Burr, G | 1 |
| Pascani, K | 1 |
| Wong, C | 1 |
| Fowler, JS | 3 |
| Wolf, AP | 2 |
| Cohen, SI | 1 |
| Mallick, JL | 1 |
| Kirkby, KC | 1 |
| Martin, F | 1 |
| Philp, M | 1 |
| Hennessy, MJ | 1 |
| Biegon, A | 1 |
| Dewey, SL | 1 |
| Saitz, R | 1 |
| Friedman, LS | 1 |
| Mayo-Smith, MF | 1 |
| Goldstein, MZ | 1 |
| Pataki, A | 1 |
| Webb, MT | 1 |
| Weingartner, HJ | 1 |
| Eckardt, MJ | 1 |
| Hommer, D | 1 |
| Johnson, DN | 1 |
| Overall, JE | 1 |
| Frecska, E | 1 |
| Piscani, K | 1 |
| Maltsberger, JT | 1 |
| D'Onofrio, G | 1 |
| Rathlev, NK | 1 |
| Ulrich, AS | 1 |
| Fish, SS | 1 |
| Freedland, ES | 1 |
| Sosis, MB | 1 |
| Matz, R | 1 |
| Seidl, JJ | 1 |
| Layde, P | 1 |
| Ripple, MG | 1 |
| Pestaner, JP | 1 |
| Levine, BS | 1 |
| Smialek, JE | 1 |
| Roberts, JS | 1 |
| Wang, W | 3 |
| Myrick, H | 3 |
| Anton, RF | 3 |
| Weiss, AP | 1 |
| Murray, GB | 1 |
| Petrovic, M | 1 |
| Pevernagie, D | 1 |
| Mariman, A | 1 |
| Van Maele, G | 1 |
| Afschrift, M | 1 |
| Longo, LP | 1 |
| Campbell, T | 1 |
| Hubatch, S | 1 |
| Roberts, J | 2 |
| Ballenger, JC | 1 |
| Shader, RI | 2 |
| Greenblatt, DJ | 1 |
| Hosein, IN | 2 |
| de Freitas, R | 2 |
| Beaubrun, MH | 2 |
| Fox, R | 1 |
| Harry, TV | 1 |
| Piepho, R | 1 |
| Whelton, A | 1 |
| Mayor, G | 1 |
| Neu, H | 1 |
| Laddu, A | 1 |
| Baron, DH | 1 |
| Sands, BF | 1 |
| Ciraulo, DA | 1 |
| Carboni, MA | 1 |
| Corsa, R | 1 |
| van Sweden, B | 1 |
| Hoste, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of N-acetylcysteine (NAC) on Treatment of Alcohol and Cocaine Use Disorders: A Double-Blind Randomized Controlled Trial.[NCT03018236] | Phase 4 | 100 participants (Anticipated) | Interventional | 2017-01-31 | Recruiting | ||
| Evaluation of the Standardised Nurse-led Approach for Risk Screening and Decrease of Alcohol Withdrawal Among Adult Inpatients With Alcohol Dependence in an Ear, Nose, Throat and Jaw Surgery Department[NCT02782156] | 89 participants (Actual) | Observational | 2014-11-30 | Completed | |||
| Phenobarbital Versus Ativan for Refractory Alcohol Withdrawal Treatment in the Intensive Care Unit[NCT04156464] | Phase 4 | 142 participants (Anticipated) | Interventional | 2020-07-06 | Recruiting | ||
| The Impact of a Pharmacist Intervention on Post-discharge Hypnotic Drug Discontinuation in Geriatric Inpatients: a Before-after Study[NCT05521971] | 173 participants (Actual) | Interventional | 2016-10-11 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for lorazepam and Alcohol Abuse
| Article | Year |
|---|---|
Paradoxical Excitation Following Intravenous Lorazepam Administration for Alcohol Withdrawal - A Case Presentation and Literature Review.
Topics: Alcoholism; Benzodiazepines; Humans; Infusions, Intravenous; Lorazepam; Male; Middle Aged; Substance | 2023 |
Beyond benzodiazepines: a meta-analysis and narrative synthesis of the efficacy and safety of alternative options for alcohol withdrawal syndrome management.
Topics: Alcoholism; Benzodiazepines; Ethanol; Humans; Lorazepam; Randomized Controlled Trials as Topic; Subs | 2023 |
Symptom-Triggered Therapy for Alcohol Withdrawal Syndrome: a Systematic Review and Meta-analysis of Randomized Controlled Trials.
Topics: Alcoholism; Benzodiazepines; Humans; Lorazepam; Randomized Controlled Trials as Topic; Substance Wit | 2019 |
Alcoholism among elderly persons.
Topics: Aged; Alcoholism; Benzodiazepines; Contraindications; Disulfiram; Humans; Incidence; Lorazepam; Ment | 1996 |
Lethal combination of tramadol and multiple drugs affecting serotonin.
Topics: Adult; Alcoholism; Analgesics, Opioid; Cyclohexanols; Dibenzothiazepines; Drug Interactions; Fatal O | 2000 |
17 trials available for lorazepam and Alcohol Abuse
| Article | Year |
|---|---|
Alcohol withdrawal prevention: a randomized evaluation of lorazepam and ethanol--a pilot study.
Topics: Acute Coronary Syndrome; Adult; Alcoholism; Central Nervous System Depressants; Drug Therapy, Combin | 2013 |
A double blind randomised comparison of chlordiazepoxide and lorazepam in alcohol withdrawal.
Topics: Adult; Alcoholism; Analysis of Variance; Chlordiazepoxide; Double-Blind Method; Humans; Hypnotics an | 2013 |
Lack of efficacy of dextromethorphan in managing alcohol withdrawal: a preliminary report of a randomized, double-blind, placebo-controlled trial.
Topics: Adult; Alcohol Abstinence; Alcohol Drinking; Alcoholism; Brain; Dextromethorphan; Double-Blind Metho | 2014 |
Coadministration of disulfiram and lorazepam in the treatment of alcohol dependence and co-occurring anxiety disorder: an open-label pilot study.
Topics: Adult; Alcoholism; Anxiety Disorders; Craving; Depressive Disorder, Major; Disulfiram; Drug Therapy, | 2016 |
A randomized, double-blind comparison of lorazepam and chlordiazepoxide in patients with uncomplicated alcohol withdrawal.
Topics: Adolescent; Adult; Alcohol-Induced Disorders; Alcoholism; Chlordiazepoxide; Drug Administration Sche | 2009 |
Pregabalin, tiapride and lorazepam in alcohol withdrawal syndrome: a multi-centre, randomized, single-blind comparison trial.
Topics: Adolescent; Adult; Aged; Alcoholism; Analgesics; Female; gamma-Aminobutyric Acid; Humans; Lorazepam; | 2010 |
Self-reported sleep, sleepiness, and repeated alcohol withdrawals: a randomized, double blind, controlled comparison of lorazepam vs gabapentin.
Topics: Adult; Aged; Alcoholism; Amines; Cyclohexanecarboxylic Acids; Disorders of Excessive Somnolence; Dou | 2007 |
Clinical symptomatology and computer analyzed EEG before, during and after anxiolytic therapy of alcohol withdrawal patients.
Topics: Adult; Alcoholism; Clinical Trials as Topic; Computers; Double-Blind Method; Electroencephalography; | 1983 |
Nonpharmacologic intervention in acute alcohol withdrawal.
Topics: Adult; Alcoholism; Double-Blind Method; Female; Humans; Lorazepam; Male; Middle Aged; Substance With | 1983 |
A comparison of the amnesic effects of lorazepam in alcoholics and non-alcoholics.
Topics: Adult; Alcoholism; Amnesia; Arousal; Humans; Lorazepam; Male; Memory; Memory, Short-Term; Orientatio | 1993 |
Impairments in reflective cognitive functions in alcoholics: a neuropharmacological model.
Topics: Alcoholism; Anti-Anxiety Agents; Case-Control Studies; Cognition Disorders; Double-Blind Method; Hum | 1994 |
Regional brain metabolic response to lorazepam in alcoholics during early and late alcohol detoxification.
Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Blood Glucose; Brain; Brain Mapping; Energy Metaboli | 1997 |
Lorazepam for the prevention of recurrent seizures related to alcohol.
Topics: Adult; Alcoholism; Anticonvulsants; Double-Blind Method; Ethanol; Female; Humans; Injections, Intrav | 1999 |
Fast withdrawal from benzodiazepines in geriatric inpatients: a randomised double-blind, placebo-controlled trial.
Topics: Aged; Aged, 80 and over; Alcoholism; Anti-Anxiety Agents; Benzodiazepines; Double-Blind Method; Fema | 2002 |
Divalproex sodium (Depakote) for alcohol withdrawal and relapse prevention.
Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Ambulatory Care; Anti-Anxiety Agents; Anticonvulsant | 2002 |
The differential effects of medication on mood, sleep disturbance, and work ability in outpatient alcohol detoxification.
Topics: Adult; Affect; Alcoholism; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Carbamazepine; Double-Blin | 2002 |
The effects of carbamazepine and lorazepam on single versus multiple previous alcohol withdrawals in an outpatient randomized trial.
Topics: Adult; Alcoholism; Ambulatory Care; Anti-Anxiety Agents; Anticonvulsants; Carbamazepine; Double-Blin | 2002 |
41 other studies available for lorazepam and Alcohol Abuse
| Article | Year |
|---|---|
Fixed-dose gabapentin augmentation in the treatment of alcohol withdrawal syndrome: a retrospective, open-label study.
Topics: Adult; Alcoholism; Benzodiazepines; Drug Tapering; Female; Gabapentin; Humans; Lorazepam; Male; Midd | 2020 |
Benzodiazepine and unhealthy alcohol use among adult outpatients.
Topics: Adolescent; Adult; Aged; Alcoholism; Anti-Anxiety Agents; Benzodiazepines; California; Cross-Section | 2019 |
Lorazepam Versus Diazepam in the Management of Emergency Department Patients With Alcohol Withdrawal.
Topics: Adult; Alcoholism; Benzodiazepines; Canada; Diazepam; Emergency Service, Hospital; Female; Hospitali | 2020 |
Assessing Propylene Glycol Toxicity in Alcohol Withdrawal Patients Receiving Intravenous Benzodiazepines: A One-Compartment Pharmacokinetic Model.
Topics: Acid-Base Equilibrium; Acidosis; Alcoholism; Benzodiazepines; Diazepam; Female; Humans; Injections, | 2018 |
Retrospective analysis of a gabapentin high dose taper compared to lorazepam in acute inpatient alcohol withdrawal.
Topics: Acute Disease; Adult; Alcoholism; Electronic Health Records; Endpoint Determination; Female; GABA Ag | 2019 |
Phenobarbital and symptom-triggered lorazepam versus lorazepam alone for severe alcohol withdrawal in the intensive care unit.
Topics: Adult; Aged; Alcoholism; Central Nervous System Agents; Drug Therapy, Combination; Ethanol; Female; | 2020 |
[High-dose zolpidem dependence].
Topics: Alcoholism; Benzodiazepines; Comorbidity; Dose-Response Relationship, Drug; Drug Tolerance; Female; | 2013 |
Drug trials in psychiatry: methodological issues.
Topics: Alcoholism; Chlordiazepoxide; Citalopram; Depressive Disorder; Diabetes Mellitus; Female; Humans; Hy | 2014 |
Cognitive control network function in alcohol use disorder before and during treatment with lorazepam.
Topics: Adult; Alcoholism; Anti-Anxiety Agents; Attention; Brain; Case-Control Studies; Cognition; Female; F | 2015 |
Old dog, new tricks: treating co-occurring anxiety and alcohol use disorders.
Topics: Alcohol-Related Disorders; Alcoholism; Anxiety; Anxiety Disorders; Disulfiram; Humans; Lorazepam; Pi | 2016 |
Hunting down a double gap metabolic acidosis.
Topics: Acidosis; Aged; Alcoholism; Fatal Outcome; Female; Humans; Kidney Failure, Chronic; Lorazepam; Pneum | 2010 |
Closing in on the gaps.
Topics: Acidosis; Aged; Alcoholism; Female; Humans; Kidney Failure, Chronic; Lorazepam; Pneumonia, Ventilato | 2010 |
Differential patterns of serum brain-derived neurotrophic factor levels in alcoholic patients with and without delirium tremens during acute withdrawal.
Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Anticonvulsants; Brain-Derived Neurotrophic Factor; | 2011 |
Subacute encephalopathy and seizures in alcoholics (SESA) presenting with non-convulsive status epilepticus.
Topics: Acetamides; Alcohol Withdrawal Seizures; Alcoholism; Anticonvulsants; Brain Diseases; Confusion; Dif | 2011 |
Agitation by sedation.
Topics: Alcoholism; Antidotes; Chemistry, Pharmaceutical; Ethylene Glycol; Female; Fomepizole; Humans; Hypno | 2003 |
Management of drug and alcohol withdrawal.
Topics: Alcoholism; Anticonvulsants; Diazepam; Half-Life; Humans; Lorazepam; Substance Withdrawal Syndrome | 2003 |
Alcohol withdrawal prophylaxis in patients undergoing surgical treatment of head and neck squamous cell carcinoma.
Topics: Adult; Aged; Alcoholism; Carcinoma, Squamous Cell; Ethanol; Female; GABA Modulators; Head and Neck N | 2005 |
Advances in alcoholism research in Germany.
Topics: Alcohol Withdrawal Delirium; Alcoholism; Animals; Brain; Comorbidity; Dopamine; Early Diagnosis; gam | 2005 |
Altered benzodiazepine receptor sensitivity in alcoholism: a study with fMRI and acute lorazepam challenge.
Topics: Adult; Alcoholism; Cerebellum; Chlormethiazole; Cognition Disorders; Drug Administration Schedule; G | 2007 |
The effect of acamprosate on alcohol and food craving in patients with alcohol dependence.
Topics: Acamprosate; Adult; Alcohol Deterrents; Alcoholism; Body Mass Index; Cognitive Behavioral Therapy; C | 2008 |
A life-threatening double gap metabolic acidosis.
Topics: Acidosis; Alcoholism; Diagnosis, Differential; Humans; Hypnotics and Sedatives; Lorazepam; Male; Mid | 2008 |
[Benzodiazepine dependence: addiction potential of the benzodiazepines is greater than previously assumed (author's transl)].
Topics: Alcoholism; Barbiturates; Benzodiazepines; Female; Hospitals, Psychiatric; Humans; Lorazepam; Male; | 1980 |
Regional brain metabolic response to lorazepam in subjects at risk for alcoholism.
Topics: Adult; Alcoholism; Brain; Brain Mapping; Deoxyglucose; Energy Metabolism; Fluorodeoxyglucose F18; Hu | 1995 |
Alcohol and benzodiazepines generate anxiety, panic and phobias.
Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Female; | 1995 |
Decreased cerebral response to inhibitory neurotransmission in alcoholics.
Topics: Adult; Alcoholism; Basal Ganglia; Brain; Cerebellum; Deoxyglucose; Fluorodeoxyglucose F18; Frontal L | 1993 |
Alcohol withdrawal: a nationwide survey of inpatient treatment practices.
Topics: Adrenergic beta-Antagonists; Alcoholism; Barbiturates; Benzodiazepines; Chlordiazepoxide; Clonidine; | 1995 |
Robert Salter: attempted suicide by jumping from a high bridge.
Topics: Adult; Alcoholism; Anti-Anxiety Agents; Antidepressive Agents; Denial, Psychological; Diagnosis, Dif | 1998 |
Lorazepam for the prevention of recurrent seizures related to alcohol.
Topics: Alcoholism; Anticonvulsants; Humans; Informed Consent; Lorazepam; Research Design; Secondary Prevent | 1999 |
Lorazepam for the prevention of recurrent seizures related to alcohol.
Topics: Alcoholism; Anticonvulsants; Humans; Lorazepam; Secondary Prevention; Seizures; Substance Withdrawal | 1999 |
Lorazepam to prevent alcohol withdrawal seizures.
Topics: Adult; Alcoholism; Anti-Anxiety Agents; Chronic Disease; Double-Blind Method; Emergency Service, Hos | 1999 |
Multiple previous detoxifications are associated with less responsive treatment and heavier drinking during an index outpatient detoxification.
Topics: Adult; Alcoholism; Ambulatory Care; Carbamazepine; Ethanol; Female; Humans; Lorazepam; Male; Middle | 2000 |
Abuse of topical analgesic.
Topics: Administration, Topical; Alcoholism; Analgesics, Non-Narcotic; Delirium; Fentanyl; Humans; Infusions | 2001 |
Clinical implications of benzodiazepine pharmacokinetics.
Topics: Administration, Oral; Adult; Age Factors; Aged; Alcoholism; Anti-Anxiety Agents; Chlordiazepoxide; C | 1977 |
Intramuscular/oral lorazepam in acute alcohol withdrawal and incipient delirium tremens.
Topics: Administration, Oral; Adult; Alcohol Withdrawal Delirium; Alcoholism; Anti-Anxiety Agents; Female; H | 1978 |
Intramuscular/oral lorazepam in acute alcohol withdrawal and incipient delirium tremens.
Topics: Acute Disease; Adult; Alcohol Withdrawal Delirium; Alcoholism; Anti-Anxiety Agents; Female; Humans; | 1979 |
Abuse of benzodiazepines.
Topics: Adult; Alcoholism; Anti-Anxiety Agents; Humans; Lorazepam; Male; Substance-Related Disorders | 1978 |
Abuse of benzodiazepines.
Topics: Alcoholism; Anti-Anxiety Agents; Chlormethiazole; Diazepam; Drug Synergism; Humans; Lorazepam; Male; | 1978 |
Grand mal status epilepticus.
Topics: Alcoholism; Anticonvulsants; Diazepam; Epilepsy, Tonic-Clonic; Ethanol; Humans; Lorazepam; Male; Mid | 1992 |
The diagnosis and treatment of panic disorder in alcoholics: three cases.
Topics: Adult; Alcohol Drinking; Alcoholism; Anxiety Disorders; Clonazepam; Diazepam; Follow-Up Studies; Hum | 1990 |
[Therapeutic use of metadoxine in alcohol-related mental and behavioral disorders].
Topics: Adult; Aged; Alcoholism; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Female; Huma | 1987 |
[Old and on the bottle again: a double stigma].
Topics: Aged; Aged, 80 and over; Alcoholism; Female; Humans; Lorazepam; Male; Substance-Related Disorders | 1987 |