Page last updated: 2024-10-30

lorazepam and Affective Psychosis, Bipolar

lorazepam has been researched along with Affective Psychosis, Bipolar in 71 studies

Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.

Research Excerpts

ExcerptRelevanceReference
"The patient was successfully treated for catatonia with lorazepam and electroconvulsive therapy after careful diagnostic workup."7.80Catatonia after deep brain stimulation successfully treated with lorazepam and right unilateral electroconvulsive therapy: a case report. ( Abbott, CC; Brodsky, A; Deligtisch, A; Evans, D; Khafaja, M; Quinn, DK; Rees, C, 2014)
"The authors describe four cases of catatonia in which topiramate treatment was used."7.73Topiramate effect in catatonia: a case series. ( McDaniel, WW; Sahota, AK; Spiegel, DR, 2006)
"Several lines of research suggested that aripiprazole might be a useful treatment for acute bipolar depression."5.13Beneficial acute antidepressant effects of aripiprazole as an adjunctive treatment or monotherapy in bipolar patients unresponsive to mood stabilizers: results from a 16-week open-label trial. ( Bria, P; Janiri, L; Mazza, M; Pecora, RD; Squillacioti, MR, 2008)
" In 3 double-blind studies, acutely agitated patients with schizophrenia (N = 311), bipolar mania (N = 201), or dementia (N = 206) were treated with intramuscular (1-3 injections/24 hrs) olanzapine (2."5.10Calming versus sedative effects of intramuscular olanzapine in agitated patients. ( Alaka, K; Battaglia, J; Lindborg, SR; Meehan, K; Wright, P, 2003)
"Nineteen patients with bipolar disorder, manic phase, received divalproex sodium 20 mg/kg/day in divided dosages for 5 days, without other psychotropic agents except lorazepam up to 4 mg/day."5.07Valproate oral loading in the treatment of acute mania. ( Bennett, JA; Keck, PE; McElroy, SL; Tugrul, KC, 1993)
"We now present data from a randomized, double-blind clinical study of lorazepam versus haloperidol in 20 hospitalized patients with a DSM-III-R diagnosis of bipolar disorder who were being treated concomitantly with lithium."5.07Adjunctive treatment of manic agitation with lorazepam versus haloperidol: a double-blind study. ( Creelman, WL; Lenox, RH; Newhouse, PA; Whitaker, TM, 1992)
"Over 67 days, 1,461 patients were screened in the ED, 269 had bipolar I or schizophrenia, 194 of whom had a contraindication to inhaled loxapine leaving 75 eligible patients; preconsent was obtained in 43 patients."3.91Study Enrollment When "Preconsent" Is Utilized for a Randomized Clinical Trial of Two Treatments for Acute Agitation in the Emergency Department. ( Cole, JB; Driver, BE; Klein, LR; Mullinax, SZ; Nordstrom, KD; Wilson, MP, 2019)
"Patients with catatonia who had more than one episode of catatonia and were treated with the lorazepam-diazepam protocol were identified."3.83Relapses and recurrences of catatonia: 30-case analysis and literature review. ( Huang, TL; Hung, YY; Lin, CC; Tsai, MC, 2016)
"The patient was successfully treated for catatonia with lorazepam and electroconvulsive therapy after careful diagnostic workup."3.80Catatonia after deep brain stimulation successfully treated with lorazepam and right unilateral electroconvulsive therapy: a case report. ( Abbott, CC; Brodsky, A; Deligtisch, A; Evans, D; Khafaja, M; Quinn, DK; Rees, C, 2014)
"Analysis 1 found that nonsedated patients with bipolar I disorder and schizophrenia showed significant decreases in PEC scores following treatment with aripiprazole IM (p < 0."3.74Intramuscular aripiprazole in the control of agitation. ( Citrome, LL; Crandall, DT; Currier, GW; Manos, G; McQuade, R; Oren, D; Pikalov, AA; Zimbroff, DL, 2007)
"The authors describe four cases of catatonia in which topiramate treatment was used."3.73Topiramate effect in catatonia: a case series. ( McDaniel, WW; Sahota, AK; Spiegel, DR, 2006)
"Aripiprazole was superior to placebo in delaying time to manic relapse (p = ."2.73Aripiprazole monotherapy for maintenance therapy in bipolar I disorder: a 100-week, double-blind study versus placebo. ( Calabrese, JR; Carlson, BX; Carson, WH; Eudicone, JM; Keck, PE; Marcus, RN; McIntyre, RS; McQuade, RD; Sanchez, R, 2007)
" Aripiprazole was dosed flexibly up to a maximum of 30 mg daily, based on tolerability and efficacy."2.73A prospective, open-label study of Aripiprazole mono- and adjunctive treatment in acute bipolar depression. ( Chriki, LS; Dunn, RT; Filkowski, MM; Ghaemi, SN; Stan, VA, 2008)
"His symptoms were consistent with catatonia, a severe motor syndrome that can be life-threatening."2.72Electroconvulsive therapy use in the adult U.S. correctional setting: A case report and literature review. ( Martin, M; Ureste, P, 2021)
" These findings suggest that intramuscular olanzapine is a safe and effective treatment for reducing acute agitation in patients with bipolar mania."2.70A double-blind, randomized comparison of the efficacy and safety of intramuscular injections of olanzapine, lorazepam, or placebo in treating acutely agitated patients diagnosed with bipolar mania. ( Breier, A; David, S; Janicak, P; Koch, M; Meehan, K; Rizk, R; Small, J; Tohen, M; Tran, P; Walker, D; Zhang, F, 2001)
"Lorazepam 4 mg/day was insufficient to produce an advantage when added to low-dose haloperidol."2.69Acute mania: haloperidol dose and augmentation with lithium or lorazepam. ( Allen, MH; Charles, O; Chou, JC; Czobor, P; Trujillo, M; Tuma, I; Volavka, J; Winsberg, B, 1999)
" Serum valproate concentrations were measured three times weekly; an unblinded investigator then adjusted dosage to produce serum concentrations between 50 and 100 mg/L."2.67Valproate in the treatment of acute mania. A placebo-controlled study. ( Hudson, JI; Keck, PE; McElroy, SL; Pope, HG, 1991)
"Treatment with lorazepam produced marked improvement in symptomatology, while treatment with clonazepam failed to demonstrate a significant therapeutic effect."2.67Double-blind comparison of the effects of clonazepam and lorazepam in acute mania. ( Bradwejn, J; Koszycki, D; Meterissian, G; Shriqui, C, 1990)
"Catatonia is often a prominent feature of the syndrome."2.49Delirious mania: detection, diagnosis, and clinical management in the acute setting. ( Bobo, WV; Heckers, S; Jacobowski, NL, 2013)
"Catatonia is a common but often overlooked motor syndrome in child and adolescent psychiatry."1.43[Catatonia is often overlooked in child and adolescent psychiatry]. ( Ballin, NH; Pagsberg, AK, 2016)
"Studies in major depressive disorder have demonstrated that suprathreshold, nondominant (right) hemisphere, unilateral electrode placement ECT has fewer adverse effects, especially cognitive adverse effects, than bitemporal ECT."1.40Successful use of right unilateral ECT for catatonia: a case series. ( Conway, C; Cristancho, P; Jewkes, D; Mon, T, 2014)
"A 37-year-old woman presented with coma unresponsive to naloxone following topiramate ingestion."1.36Clinical effects and toxicokinetic evaluation following massive topiramate ingestion. ( Krasowski, MD; Lynch, MJ; Pizon, AF; Siam, MG, 2010)
" A full pharmacokinetic time profile of lithium was obtained."1.31Bayesian pharmacokinetics of lithium after an acute self-intoxication and subsequent haemodialysis: a case report. ( Beijnen, JH; Kerbusch, T; Mathôt, RA; Meesters, EW; Otten, HM; Schellens, JH; van Kan, HJ, 2002)
"Three patients had exceptionally high seizure threshold, as determined by an empirical titration procedure."1.29Exceptionally high seizure threshold: ECT device limitations. ( Devanand, DP; Lisanby, SH; Mullen, L; Nobler, MS; Prudic, J; Sackeim, HA, 1996)
"A 48-year-old, right-handed man had a cerebral infarct over the left temporal region."1.29Bipolar disorder following a stroke involving the left hemisphere. ( Fuh, JL; Liu, CY; Liu, HC; Wang, SJ; Yang, YY, 1996)
"The benzodiazepine withdrawal symptoms are presented here."1.27Manic-like reaction induced by lorazepam withdrawal. ( Labelle, A; Lapierre, YD, 1987)
" Subsequent administration of an equivalent dosage of lorazepam did not induce manic symptoms."1.27A case of alprazolam, but not lorazepam, inducing manic symptoms. ( Charney, DS; Goodman, WK, 1987)

Research

Studies (71)

TimeframeStudies, this research(%)All Research%
pre-199016 (22.54)18.7374
1990's12 (16.90)18.2507
2000's23 (32.39)29.6817
2010's18 (25.35)24.3611
2020's2 (2.82)2.80

Authors

AuthorsStudies
Fernandez, A1
Pendaries, G1
Dor, E1
Askenazy, F1
Thümmler, S1
Martin, M1
Ureste, P1
Cole, JB1
Klein, LR1
Mullinax, SZ1
Nordstrom, KD1
Driver, BE1
Wilson, MP1
Quinn, DK1
Rees, C1
Brodsky, A1
Deligtisch, A1
Evans, D1
Khafaja, M1
Abbott, CC1
Cristancho, P1
Jewkes, D1
Mon, T1
Conway, C1
Lee, SY1
Chen, SL1
Chang, YH1
Chen, PS1
Huang, SY2
Tzeng, NS2
Wang, CL1
Wang, LJ1
Lee, IH1
Wang, TY1
Chen, KC1
Yang, YK1
Hong, JS1
Lu, RB2
van Ham, C1
Schrijvers, D1
De Picker, L1
Vandendriessche, F1
Sabbe, B1
Barnhorst, A1
Xiong, GL1
Chou, PH1
Ouyang, WC1
Lan, TH1
Chan, CH1
Ford, N1
Ludbrook, G1
Galletly, C1
Ballin, NH1
Pagsberg, AK1
Lin, CC1
Hung, YY1
Tsai, MC1
Huang, TL1
Knapen, SE1
Riemersma-van der Lek, RF1
Haarman, BC1
Schoevers, RA1
Önen, Ö1
Kutlu, A1
Erkuran, HÖ1
Mazza, M1
Squillacioti, MR1
Pecora, RD1
Janiri, L1
Bria, P1
Kruszewski, SP1
Paczynski, R1
Hardy, D1
Sekhar, S1
Kalra, B1
Mendhekar, DN1
Tekur, U1
Lynch, MJ1
Pizon, AF1
Siam, MG1
Krasowski, MD1
Binbay, T1
Danivas, V1
Behere, RV1
Varambally, S1
Rao, NP1
Venkatasubramanian, G1
Gangadhar, BN1
Hung Chi, M1
Hua Chang, H1
Chou, KR1
Chun Tsai, H1
Kuang Yang, Y1
See Chen, P1
Jacobowski, NL1
Heckers, S1
Bobo, WV1
Yatham, LN1
Grossman, F2
Augustyns, I1
Vieta, E2
Ravindran, A1
Battaglia, J1
Lindborg, SR1
Alaka, K1
Meehan, K2
Wright, P1
Coffey, B1
Curtin, F1
Schulz, P1
Smulevich, AB1
Khanna, S1
Eerdekens, M1
Karcher, K1
Kramer, M1
Mamah, D1
Hong, BA1
Chapman, WC1
Pruett, JR1
Rizvi, ST1
Lewin, MR1
Montauk, L1
Shalit, M1
Nobay, F1
Sheehan, W1
Thurber, S1
McDaniel, WW1
Spiegel, DR1
Sahota, AK1
Zimbroff, DL2
Marcus, RN2
Manos, G2
Stock, E1
McQuade, RD2
Auby, P1
Oren, DA1
Currier, GW1
Citrome, LL1
Oren, D1
McQuade, R1
Pikalov, AA1
Crandall, DT1
Rodriguez, LJ1
Keck, PE3
Calabrese, JR1
McIntyre, RS1
Carson, WH1
Eudicone, JM1
Carlson, BX1
Sanchez, R1
Miller, MA1
Levsky, ME1
Dunn, RT1
Stan, VA1
Chriki, LS1
Filkowski, MM1
Ghaemi, SN1
Cruz, N1
García-Campayo, J1
de Arce, R1
Manuel Crespo, J1
Vallès, V1
Pérez-Blanco, J1
Roca, E1
Manuel Olivares, J1
Moríñigo, A1
Fernández-Villamor, R1
Comes, M1
Fouks, L1
Widlocher, D1
Lecrubier, Y1
Le Goc, Y1
Galynker, II1
Rosenthal, RN1
Perkel, C1
Shwartz, A1
McElroy, SL2
Tugrul, KC1
Bennett, JA1
Finnerty, M1
Levin, Z1
Miller, LJ1
Lisanby, SH1
Devanand, DP1
Nobler, MS1
Prudic, J1
Mullen, L1
Sackeim, HA1
Liu, CY1
Wang, SJ1
Fuh, JL1
Yang, YY1
Liu, HC1
Post, RM1
Ketter, TA1
Denicoff, K1
Pazzaglia, PJ1
Leverich, GS1
Marangell, LB1
Callahan, AM1
George, MS1
Frye, MA1
Rosenfeld, MJ1
Friedman, JH1
Chou, JC1
Czobor, P1
Charles, O1
Tuma, I1
Winsberg, B1
Allen, MH1
Trujillo, M1
Volavka, J1
Zhang, F1
David, S1
Tohen, M1
Janicak, P1
Small, J1
Koch, M1
Rizk, R1
Walker, D1
Tran, P1
Breier, A1
Kafantaris, V1
Coletti, DJ1
Dicker, R1
Padula, G1
Kane, JM1
Kerbusch, T1
Mathôt, RA1
Otten, HM1
Meesters, EW1
van Kan, HJ1
Schellens, JH1
Beijnen, JH1
Singer, L1
Finance, MF1
Ruh, MD1
Lenox, RH3
Newhouse, PA1
Creelman, WL1
Whitaker, TM1
Pope, HG1
Hudson, JI1
Bradwejn, J1
Shriqui, C1
Koszycki, D1
Meterissian, G1
Salzman, C1
Miyawaki, EK1
Soloman, D1
Yassa, R1
Groulx, B1
Santos, AB1
Morton, WA1
Rigby, J1
Harvey, M1
Davies, DR1
Jobling, M1
Stein, G1
Chouinard, G1
Dever, A1
Schweizer, E1
Cohen, S1
Khan, A1
Burke, WJ1
Lapierre, YD1
Labelle, A1
Majeau-Chargois, D1
Goodman, WK1
Charney, DS1
Modell, JG2
Weiner, S2

Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
An Observational Study of Anti-Psychotic Medication for the Treatment of Agitation in the Emergency Department[NCT02877108]100 participants (Anticipated)Observational2016-04-30Recruiting
Double Blind Placebo Controlled Trial of a Protein Kinase C Inhibitor: Tamoxifen Citrate in Treatment of Acute Mania[NCT00411203]Phase 366 participants (Actual)Interventional2003-04-30Completed
The Safety And Efficacy Of Risperdal� (Risperidone) Versus Placebo As Add-On Therapy To Mood Stabilizers In The Treatment Of The Manic Phase Of Bipolar Disorder[NCT00250367]Phase 3151 participants (Actual)Interventional1997-10-31Completed
The Efficacy And Safety Of Flexible Dose Ranges Of Risperidone Versus Placebo Or Haloperidol In The Treatment Of Manic Episodes Associated With Bipolar I Disorder.[NCT00253162]Phase 3439 participants (Actual)Interventional2001-03-31Completed
[NCT00036348]Phase 30 participants Interventional2000-03-31Completed
A Multi-center, Randomized, Double-blind, Parallel Group, Placebo-controlled 52 Weeks Clinical Trial to Evaluate Efficacy and Safety of Oxcarbazepine p.o.(300-1200 mg/Day) as Adjuvant Therapy in the Bipolar Disorder I or II Treatment[NCT00154323]Phase 455 participants (Actual)Interventional2003-01-31Completed
Effect of Bupropion on Seizure Threshold in Depressed Patients[NCT03126682]Phase 410 participants (Actual)Interventional2017-08-25Completed
Treatment and Outcome of Early Onset Bipolar Disorder[NCT00048802]Phase 440 participants Interventional2002-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in MADRS Score

Scoring of depressive symptoms on the Montgomery Asberg Depression Rating Scale, maximum 60 , minimum 0. Higher scores mean worse outcome. First measurement on day 1 of electroconvulsive treatment (ECT) and second measurement on day 2 of electroconvulsive therapy (ECT), separated by 1 day interval. This outcome measure was not measured at baseline. (NCT03126682)
Timeframe: Scored on day 1 and day 2 after ECT session

InterventionScored on a scale (Mean)
Wellbutrin During ECT 12.60
Wellbutrin During ECT 23.60

Change in Seizure Duration

Duration of seizures with ECT. First measurement on day 1 of electroconvulsive treatment (ECT) and second measurement on day 2 of electroconvulsive therapy (ECT), separated by 1 day interval. This outcome measure was not measured at baseline. (NCT03126682)
Timeframe: Measured at day 1 and day 2

Interventionseconds (Mean)
Wellbutrin During ECT 126.2
Wellbutrin During ECT 229.6

Change in Seizure Threshold

Charge in Millicoulombs at which subject gets a seizure with ECT. First measurement on day 1 of electroconvulsive treatment (ECT) and second measurement on day 2 of electroconvulsive therapy (ECT), separated by 1 day interval. This outcome measure was not measured at baseline. (NCT03126682)
Timeframe: Measured at day 1 and day 2

Interventionmillicoulombs (Mean)
Wellbutrin During ECT 123.04
Wellbutrin During ECT 219.68

Reviews

4 reviews available for lorazepam and Affective Psychosis, Bipolar

ArticleYear
Electroconvulsive therapy use in the adult U.S. correctional setting: A case report and literature review.
    Journal of forensic sciences, 2021, Volume: 66, Issue:3

    Topics: Bipolar Disorder; Catatonia; Creatine Kinase; Electroconvulsive Therapy; Health Services Accessibili

2021
Delirious mania: detection, diagnosis, and clinical management in the acute setting.
    Journal of psychiatric practice, 2013, Volume: 19, Issue:1

    Topics: Bipolar Disorder; Catatonia; Delirium; Electroconvulsive Therapy; Humans; Hypnotics and Sedatives; L

2013
Clonazepam and lorazepam in acute mania: a Bayesian meta-analysis.
    Journal of affective disorders, 2004, Volume: 78, Issue:3

    Topics: Bayes Theorem; Bipolar Disorder; Clonazepam; GABA Modulators; Humans; Lorazepam; Placebos; Randomize

2004
The place of anticonvulsant therapy in bipolar illness.
    Psychopharmacology, 1996, Volume: 128, Issue:2

    Topics: Affect; Anticonvulsants; Bipolar Disorder; Calcium Channel Blockers; Carbamazepine; Clonazepam; Drug

1996

Trials

19 trials available for lorazepam and Affective Psychosis, Bipolar

ArticleYear
Correlation of plasma brain-derived neurotrophic factor and metabolic profiles in drug-naïve patients with bipolar II disorder after a twelve-week pharmacological intervention.
    Acta psychiatrica Scandinavica, 2015, Volume: 131, Issue:2

    Topics: Adult; Affect; Bipolar Disorder; Body Mass Index; Brain-Derived Neurotrophic Factor; Cholesterol; Fe

2015
Beneficial acute antidepressant effects of aripiprazole as an adjunctive treatment or monotherapy in bipolar patients unresponsive to mood stabilizers: results from a 16-week open-label trial.
    Expert opinion on pharmacotherapy, 2008, Volume: 9, Issue:18

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Ag

2008
Efficacy of sodium valproate and haloperidol in the management of acute mania: a randomized open-label comparative study.
    Journal of clinical pharmacology, 2010, Volume: 50, Issue:6

    Topics: Adolescent; Adult; Antimanic Agents; Bipolar Disorder; Dyskinesia, Drug-Induced; Female; Haloperidol

2010
Mood stabilisers plus risperidone or placebo in the treatment of acute mania. International, double-blind, randomised controlled trial.
    The British journal of psychiatry : the journal of mental science, 2003, Volume: 182

    Topics: Adult; Aged; Antimanic Agents; Antipsychotic Agents; Basal Ganglia Diseases; Bipolar Disorder; Brief

2003
Calming versus sedative effects of intramuscular olanzapine in agitated patients.
    The American journal of emergency medicine, 2003, Volume: 21, Issue:3

    Topics: Adult; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Dementia; Doubl

2003
Acute and continuation risperidone monotherapy in bipolar mania: a 3-week placebo-controlled trial followed by a 9-week double-blind trial of risperidone and haloperidol.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2005, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Bipolar Disorder; Dopamine Antagonists; Double-Blind

2005
Management of acute agitation in patients with bipolar disorder: efficacy and safety of intramuscular aripiprazole.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:2

    Topics: Acute Disease; Adult; Anti-Anxiety Agents; Antipsychotic Agents; Aripiprazole; Bipolar Disorder; Dis

2007
Aripiprazole monotherapy for maintenance therapy in bipolar I disorder: a 100-week, double-blind study versus placebo.
    The Journal of clinical psychiatry, 2007, Volume: 68, Issue:10

    Topics: Adult; Antipsychotic Agents; Aripiprazole; Bipolar Disorder; Depression; Diagnostic and Statistical

2007
A prospective, open-label study of Aripiprazole mono- and adjunctive treatment in acute bipolar depression.
    Journal of affective disorders, 2008, Volume: 110, Issue:1-2

    Topics: Acute Disease; Adolescent; Adult; Akathisia, Drug-Induced; Ambulatory Care; Antidepressive Agents; A

2008
A double-blind, randomized, placebo-controlled prophylaxis trial of oxcarbazepine as adjunctive treatment to lithium in the long-term treatment of bipolar I and II disorder.
    The international journal of neuropsychopharmacology, 2008, Volume: 11, Issue:4

    Topics: Adult; Antimanic Agents; Bipolar Disorder; Carbamazepine; Double-Blind Method; Drug Therapy, Combina

2008
Valproate oral loading in the treatment of acute mania.
    The Journal of clinical psychiatry, 1993, Volume: 54, Issue:8

    Topics: Acute Disease; Administration, Oral; Adult; Bipolar Disorder; Drug Therapy, Combination; Female; Hos

1993
Acute mania: haloperidol dose and augmentation with lithium or lorazepam.
    Journal of clinical psychopharmacology, 1999, Volume: 19, Issue:6

    Topics: Adult; Aged; Anti-Anxiety Agents; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Citrates

1999
A double-blind, randomized comparison of the efficacy and safety of intramuscular injections of olanzapine, lorazepam, or placebo in treating acutely agitated patients diagnosed with bipolar mania.
    Journal of clinical psychopharmacology, 2001, Volume: 21, Issue:4

    Topics: Adult; Affect; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Choline

2001
Adjunctive treatment of manic agitation with lorazepam versus haloperidol: a double-blind study.
    The Journal of clinical psychiatry, 1992, Volume: 53, Issue:2

    Topics: Adult; Aged; Aggression; Bipolar Disorder; Double-Blind Method; Drug Therapy, Combination; Female; H

1992
Valproate in the treatment of acute mania. A placebo-controlled study.
    Archives of general psychiatry, 1991, Volume: 48, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Bipolar Disorder; Double-Blind Method; Drug Administration S

1991
Double-blind comparison of the effects of clonazepam and lorazepam in acute mania.
    Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:6

    Topics: Acute Disease; Adult; Bipolar Disorder; Clonazepam; Double-Blind Method; Drug Therapy, Combination;

1990
Use of benzodiazepines.
    Hospital & community psychiatry, 1990, Volume: 41, Issue:3

    Topics: Bipolar Disorder; Clinical Trials as Topic; Humans; Lorazepam; Psychomotor Agitation

1990
Use of benzodiazepines to improve management of manic agitation.
    Hospital & community psychiatry, 1989, Volume: 40, Issue:10

    Topics: Bipolar Disorder; Clinical Trials as Topic; Clonazepam; Drug Administration Schedule; Humans; Loraze

1989
The use of benzodiazepines in the treatment of manic-depressive illness.
    The Journal of clinical psychiatry, 1988, Volume: 49 Suppl

    Topics: Acute Disease; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Basal Ga

1988

Other Studies

48 other studies available for lorazepam and Affective Psychosis, Bipolar

ArticleYear
[Malignant neuroleptic syndrome: An atypical case in an adolescent affected by bipolar I disorder associated with catatonic syndrome].
    L'Encephale, 2020, Volume: 46, Issue:2

    Topics: Adolescent; Antipsychotic Agents; Bipolar Disorder; Catatonia; Electroencephalography; Humans; Hypno

2020
Study Enrollment When "Preconsent" Is Utilized for a Randomized Clinical Trial of Two Treatments for Acute Agitation in the Emergency Department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2019, Volume: 26, Issue:5

    Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Emergency Service, Hospital; Ethics, Research; Female

2019
Catatonia after deep brain stimulation successfully treated with lorazepam and right unilateral electroconvulsive therapy: a case report.
    The journal of ECT, 2014, Volume: 30, Issue:3

    Topics: Aged; Anti-Anxiety Agents; Bipolar Disorder; Catatonia; Combined Modality Therapy; Deep Brain Stimul

2014
Successful use of right unilateral ECT for catatonia: a case series.
    The journal of ECT, 2014, Volume: 30, Issue:1

    Topics: Adolescent; Adult; Aged, 80 and over; Antipsychotic Agents; Bipolar Disorder; Catatonia; Depressive

2014
Neuropsychiatric features in Behçet's disease: a case report.
    Clinical neurology and neurosurgery, 2014, Volume: 127

    Topics: Adult; Antipsychotic Agents; Behcet Syndrome; Bipolar Disorder; Brain; Butyrophenones; Diagnostic an

2014
Pulmonary embolism in a psychiatric patient.
    The American journal of psychiatry, 2014, Nov-01, Volume: 171, Issue:11

    Topics: Adult; Aggression; Antipsychotic Agents; Autopsy; Benzodiazepines; Bipolar Disorder; Catatonia; Deat

2014
Secondary mania due to AIDS and cryptococcal meningitis in a 78-year-old patient.
    Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2016, Volume: 16, Issue:2

    Topics: Aged; AIDS-Related Opportunistic Infections; Antipsychotic Agents; Bipolar Disorder; Cryptococcus ne

2016
Benzodiazepines may reduce the effectiveness of ketamine in the treatment of depression.
    The Australian and New Zealand journal of psychiatry, 2015, Volume: 49, Issue:12

    Topics: Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; De

2015
[Catatonia is often overlooked in child and adolescent psychiatry].
    Ugeskrift for laeger, 2016, Jan-11, Volume: 177, Issue:2

    Topics: Adolescent; Adolescent Psychiatry; Anticonvulsants; Bipolar Disorder; Catatonia; Child Psychiatry; H

2016
Relapses and recurrences of catatonia: 30-case analysis and literature review.
    Comprehensive psychiatry, 2016, Volume: 66

    Topics: Adolescent; Adult; Antipsychotic Agents; Bipolar Disorder; Catatonia; Clozapine; Depressive Disorder

2016
Coping with a life event in bipolar disorder: ambulatory measurement, signalling and early treatment.
    BMJ case reports, 2016, Oct-13, Volume: 2016

    Topics: Adaptation, Psychological; Adult; Ambulatory Care; Bipolar Disorder; Female; Humans; Hypnotics and S

2016
Treating an Adolescent with Long QT Syndrome for Bipolar Disorder: A Case Presentation.
    Psychopharmacology bulletin, 2017, 01-26, Volume: 47, Issue:1

    Topics: Adolescent; Bipolar Disorder; Female; Humans; Long QT Syndrome; Lorazepam; Risperidone; Valproic Aci

2017
Concomitant use of Lorazepam with tamoxifen in bipolar mania clinical trials.
    Archives of general psychiatry, 2009, Volume: 66, Issue:1

    Topics: Anticonvulsants; Bipolar Disorder; Double-Blind Method; Drug Therapy, Combination; Humans; Lorazepam

2009
You're the flight surgeon: a psychiatric patient in a combat zone.
    Aviation, space, and environmental medicine, 2009, Volume: 80, Issue:8

    Topics: Adult; Air Ambulances; Anti-Anxiety Agents; Bipolar Disorder; Humans; Iraq War, 2003-2011; Lorazepam

2009
Clinical effects and toxicokinetic evaluation following massive topiramate ingestion.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2010, Volume: 6, Issue:2

    Topics: Acidosis; Adult; Anticonvulsants; Bipolar Disorder; Blood Gas Analysis; Coma; Critical Care; Drug Ov

2010
[First-episode mania with psychotic features induced by over-the-counter diet aids containing sibutramine].
    Turk psikiyatri dergisi = Turkish journal of psychiatry, 2010,Winter, Volume: 21, Issue:4

    Topics: Appetite Depressants; Bipolar Disorder; Cyclobutanes; Humans; Hypnotics and Sedatives; Lorazepam; No

2010
Electroconvulsive therapy in the treatment of delirious mania: a report of 2 patients.
    The journal of ECT, 2010, Volume: 26, Issue:4

    Topics: Adolescent; Antimanic Agents; Bipolar Disorder; Catatonia; Delirium; Electroconvulsive Therapy; Fema

2010
The prevalence of metabolic syndrome in drug-naïve bipolar II disorder patients before and after twelve week pharmacological intervention.
    Journal of affective disorders, 2013, Mar-20, Volume: 146, Issue:1

    Topics: Adult; Antimanic Agents; Bipolar Disorder; Body Mass Index; Diagnostic and Statistical Manual of Men

2013
Clinical case presentation: therapeutic challenges in adolescent-onset bipolar disorder.
    Journal of child and adolescent psychopharmacology, 2003,Winter, Volume: 13, Issue:4

    Topics: Adolescent; Aggression; Anti-Anxiety Agents; Antimanic Agents; Antipsychotic Agents; Bipolar Disorde

2003
Liver transplantation in a patient with undiagnosed bipolar disorder.
    Transplantation proceedings, 2004, Volume: 36, Issue:9

    Topics: Bipolar Disorder; Female; Hepatitis C; Humans; Liver Diseases, Alcoholic; Liver Transplantation; Lor

2004
A16-year-old girl with excited catatonia treated with low-dose oral Lorazepam.
    Journal of child and adolescent psychopharmacology, 2005, Volume: 15, Issue:6

    Topics: Adolescent; Bipolar Disorder; Catatonia; Delirium; Dose-Response Relationship, Drug; Female; Humans;

2005
An unusual case of subterfuge in the emergency department: covert administration of antipsychotic and anxiolytic medications to control an agitated patient.
    Annals of emergency medicine, 2006, Volume: 47, Issue:1

    Topics: Administration, Oral; Adult; Anti-Anxiety Agents; Antipsychotic Agents; Beverages; Bipolar Disorder;

2006
SPECT and neuropsychological measures of lithium toxicity.
    The Australian and New Zealand journal of psychiatry, 2006, Volume: 40, Issue:3

    Topics: Aged; Antimanic Agents; Bipolar Disorder; Brain; Cerebellum; Dibenzothiazepines; Dose-Response Relat

2006
Topiramate effect in catatonia: a case series.
    The Journal of neuropsychiatry and clinical neurosciences, 2006,Spring, Volume: 18, Issue:2

    Topics: Adult; Aged; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Cataplexy; Catatonia; Dose-Res

2006
Intramuscular aripiprazole in the control of agitation.
    Journal of psychiatric practice, 2007, Volume: 13, Issue:3

    Topics: Adult; Antipsychotic Agents; Aripiprazole; Arousal; Bipolar Disorder; Dose-Response Relationship, Dr

2007
A closer look: the benefits and effectiveness of cognitive behavioral therapy on a female-specific unit for treatment of bipolar disorder.
    Issues in mental health nursing, 2007, Volume: 28, Issue:5

    Topics: Adult; Bipolar Disorder; Cognitive Behavioral Therapy; Female; Health Knowledge, Attitudes, Practice

2007
Choreiform dyskinesia following isolated lamotrigine overdose.
    Journal of child neurology, 2008, Volume: 23, Issue:2

    Topics: Adult; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Chorea; Drug Overdose; Dyskinesia, Drug-

2008
[Lorazepam. Evaluation after extensive use].
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1981, Volume: 22, Issue:C

    Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Bipolar Disorder; Depressive Disorder; Dogs; Humans

1981
The place of anxiety in depressive symptomatology.
    British journal of clinical pharmacology, 1983, Volume: 15 Suppl 2

    Topics: Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Bipolar Disorder; Clorazepate Dipotas

1983
Doxepin withdrawal mania.
    The Journal of clinical psychiatry, 1995, Volume: 56, Issue:3

    Topics: Bipolar Disorder; Doxepin; Drug Therapy, Combination; Female; Humans; Lithium; Lorazepam; Middle Age

1995
Acute manic episodes in pregnancy.
    The American journal of psychiatry, 1996, Volume: 153, Issue:2

    Topics: Adult; Bipolar Disorder; Chlorpromazine; Comorbidity; Diabetes Mellitus, Type 1; Drug Therapy, Combi

1996
Exceptionally high seizure threshold: ECT device limitations.
    Convulsive therapy, 1996, Volume: 12, Issue:3

    Topics: Aged; Aged, 80 and over; Anti-Anxiety Agents; Bipolar Disorder; Depressive Disorder; Electroconvulsi

1996
Bipolar disorder following a stroke involving the left hemisphere.
    The Australian and New Zealand journal of psychiatry, 1996, Volume: 30, Issue:5

    Topics: Bipolar Disorder; Cerebral Infarction; Dominance, Cerebral; Drug Therapy, Combination; Haloperidol;

1996
Catatonia responsive to lorazepam: a case report.
    Movement disorders : official journal of the Movement Disorder Society, 1999, Volume: 14, Issue:1

    Topics: Aged; Bipolar Disorder; Catatonia; Diagnosis, Differential; Female; Hip Fractures; Humans; Lorazepam

1999
Adjunctive antipsychotic treatment of adolescents with bipolar psychosis.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2001, Volume: 40, Issue:12

    Topics: Adolescent; Antipsychotic Agents; Bipolar Disorder; Child; Drug Therapy, Combination; Female; Humans

2001
Bayesian pharmacokinetics of lithium after an acute self-intoxication and subsequent haemodialysis: a case report.
    Pharmacology & toxicology, 2002, Volume: 90, Issue:5

    Topics: Acute Disease; Acute Kidney Injury; Adult; Antimanic Agents; Antipsychotic Agents; Bayes Theorem; Bi

2002
[Pulmonary embolisms occurring in 1 month in 3 aged women with manic-depressive psychoses. Discussion. Etiopathogenic role or psychiatric treatment].
    Annales medico-psychologiques, 1975, Volume: 1, Issue:2

    Topics: Aged; Antidepressive Agents; Bipolar Disorder; Chlorpromazine; Clomipramine; Depressive Disorder, Ma

1975
Lorazepam in the treatment of lithium-induced akathisia.
    Journal of clinical psychopharmacology, 1989, Volume: 9, Issue:1

    Topics: Akathisia, Drug-Induced; Bipolar Disorder; Drug Therapy, Combination; Humans; Lithium; Lithium Carbo

1989
Mania precipitated by benzodiazepine withdrawal.
    Acta psychiatrica Scandinavica, 1989, Volume: 79, Issue:4

    Topics: Aged; Aged, 80 and over; Bipolar Disorder; Cyclothymic Disorder; Female; Humans; Lorazepam; Mood Dis

1989
Lorazepam in resistant mania.
    Lancet (London, England), 1986, Mar-01, Volume: 1, Issue:8479

    Topics: Bipolar Disorder; Humans; Lorazepam; Male; Middle Aged

1986
Rapid remission of organic mania after treatment with lorazepam.
    Journal of clinical psychopharmacology, 1988, Volume: 8, Issue:3

    Topics: Bipolar Disorder; Female; Humans; Lorazepam; Middle Aged; Neurocognitive Disorders

1988
Respiratory distress with use of lorazepam in mania.
    Journal of clinical psychopharmacology, 1987, Volume: 7, Issue:3

    Topics: Adult; Bipolar Disorder; Female; Humans; Lorazepam; Respiratory Insufficiency

1987
Benzodiazepine-induced hypomania?
    Journal of clinical psychopharmacology, 1987, Volume: 7, Issue:5

    Topics: Bipolar Disorder; Humans; Lorazepam; Male; Middle Aged

1987
Manic-like reaction induced by lorazepam withdrawal.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1987, Volume: 32, Issue:8

    Topics: Anxiety Disorders; Bipolar Disorder; Female; Humans; Lorazepam; Middle Aged; Sleep Initiation and Ma

1987
Lorazepam and manic agitation.
    The American journal of psychiatry, 1986, Volume: 143, Issue:9

    Topics: Adult; Bipolar Disorder; Humans; Lorazepam; Male; Myocardial Infarction; Psychomotor Agitation

1986
A case of alprazolam, but not lorazepam, inducing manic symptoms.
    The Journal of clinical psychiatry, 1987, Volume: 48, Issue:3

    Topics: Adult; Alprazolam; Anxiety Disorders; Bipolar Disorder; Female; Humans; Lorazepam; Panic

1987
Acute treatment of manic agitation with lorazepam.
    Psychosomatics, 1986, Volume: 27, Issue:1 Suppl

    Topics: Acute Disease; Bipolar Disorder; Humans; Injections, Intramuscular; Lorazepam; Psychomotor Agitation

1986
Inpatient clinical trial of lorazepam for the management of manic agitation.
    Journal of clinical psychopharmacology, 1985, Volume: 5, Issue:2

    Topics: Adult; Ataxia; Bipolar Disorder; Delirium; Female; Humans; Lorazepam; Male; Middle Aged; Mood Disord

1985