lorazepam has been researched along with Adverse Drug Event in 8 studies
Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Primary outcome was seizure cessation for 1h, and secondary outcomes were 24h seizure remission, in-hospital death, and severe adverse events (SAE)." | 6.84 | Comparison of lacosamide versus sodium valproate in status epilepticus: A pilot study. ( Dubey, D; Kalita, J; Misra, UK, 2017) |
| "Four randomized, double-blind, placebo-controlled, 4-period drug-drug interaction studies were conducted in healthy subjects to evaluate the pharmacokinetic and pharmacodynamic (PD) interactions between mirogabalin and commonly used central nervous system depressants." | 2.87 | Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Mirogabalin When Coadministered With Lorazepam, Zolpidem, Tramadol, or Ethanol: Results From Drug-Drug Interaction Studies in Healthy Subjects. ( Currie, A; Dishy, V; Dow, J; He, L; Ishizuka, H; Jansen, M; Mendell, J; Merante, D; Zahir, H, 2018) |
| "Primary outcome was seizure cessation for 1h, and secondary outcomes were 24h seizure remission, in-hospital death, and severe adverse events (SAE)." | 2.84 | Comparison of lacosamide versus sodium valproate in status epilepticus: A pilot study. ( Dubey, D; Kalita, J; Misra, UK, 2017) |
| "Polypharmacy increases the risk of potential drug-drug interactions (pDDIs)." | 1.72 | Clinical significance of potential drug-drug interactions in older adults with psychiatric disorders: a retrospective study. ( Cui, Y; Ding, Y; Ji, M; Liu, Y; Wang, D; Wang, H; Yang, M; Zhang, H; Zhuang, T, 2022) |
| "Propofol is an addictive drug, and the problem of its abuse and dependence has occurred." | 1.42 | Increased use in propofol and reported patterns of adverse events among anesthetics in Korea. ( Kim, MH; Park, BJ; Park, HJ; Shin, JY, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 1 |
| Liu, Y | 1 |
| Yang, M | 1 |
| Ding, Y | 1 |
| Wang, H | 2 |
| Zhang, H | 1 |
| Wang, D | 1 |
| Zhuang, T | 1 |
| Ji, M | 1 |
| Cui, Y | 1 |
| Misra, UK | 1 |
| Dubey, D | 1 |
| Kalita, J | 1 |
| Jansen, M | 1 |
| Mendell, J | 1 |
| Currie, A | 1 |
| Dow, J | 1 |
| He, L | 1 |
| Merante, D | 1 |
| Dishy, V | 1 |
| Ishizuka, H | 1 |
| Zahir, H | 1 |
| Park, HJ | 1 |
| Shin, JY | 1 |
| Kim, MH | 1 |
| Park, BJ | 1 |
| Garbe, E | 1 |
| Andersohn, F | 1 |
| Bronder, E | 1 |
| Klimpel, A | 1 |
| Thomae, M | 1 |
| Schrezenmeier, H | 1 |
| Hildebrandt, M | 1 |
| Späth-Schwalbe, E | 1 |
| Grüneisen, A | 1 |
| Mayer, B | 1 |
| Salama, A | 1 |
| Kurtal, H | 1 |
| Preskorn, SH | 1 |
| Brahams, D | 1 |
2 trials available for lorazepam and Adverse Drug Event
| Article | Year |
|---|---|
Comparison of lacosamide versus sodium valproate in status epilepticus: A pilot study.
Topics: Acetamides; Administration, Intravenous; Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants | 2017 |
Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Mirogabalin When Coadministered With Lorazepam, Zolpidem, Tramadol, or Ethanol: Results From Drug-Drug Interaction Studies in Healthy Subjects.
Topics: Adolescent; Adult; Bridged Bicyclo Compounds; Drug Interactions; Drug-Related Side Effects and Adver | 2018 |
6 other studies available for lorazepam and Adverse Drug Event
| Article | Year |
|---|---|
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Clinical significance of potential drug-drug interactions in older adults with psychiatric disorders: a retrospective study.
Topics: Aged; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Humans; Lorazepam; Mental | 2022 |
Increased use in propofol and reported patterns of adverse events among anesthetics in Korea.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Anesthetics, Intravenous; Child; C | 2015 |
Drug induced immune haemolytic anaemia in the Berlin Case-Control Surveillance Study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Hemolytic, Autoimmune; Anti-Bacterial Agents; An | 2011 |
Multiple medication use presenting as Parkinson's dementia complex: a message from Titanic.
Topics: Aged; Anti-Infective Agents; Antiparkinson Agents; Antipsychotic Agents; Bacteriuria; Ciprofloxacin; | 2008 |
Iatrogenic crime: criminal behaviour in patients receiving drug treatment.
Topics: Accidents, Traffic; Adult; Behavior; Crime; Diazepam; Drug-Related Side Effects and Adverse Reaction | 1987 |