lorazepam has been researched along with Acute Lymphoid Leukemia in 6 studies
Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nausea was observed in 51/71 patients (72%) and 93/164 cycles (57%)." | 5.51 | Impact of adjuvant lorazepam with granisetron on chemotherapy-induced nausea and vomiting in pediatric patients with acute lymphoblastic leukemia. ( Goldman, RD; Hasegawa, D; Kishimoto, K; Kosaka, Y; Ono, A, 2019) |
| "Nausea was observed in 51/71 patients (72%) and 93/164 cycles (57%)." | 1.51 | Impact of adjuvant lorazepam with granisetron on chemotherapy-induced nausea and vomiting in pediatric patients with acute lymphoblastic leukemia. ( Goldman, RD; Hasegawa, D; Kishimoto, K; Kosaka, Y; Ono, A, 2019) |
| "Oral lorazepam was tolerated by the patients, but all patients needed dose reduction due to some adverse effects." | 1.36 | Oral lorazepam prevents seizure during high-dose busulfan in children undergoing hematopoietic stem cell transplantation: a prospective study. ( Amini, M; Ghavamzadeh, A; Hadjibabaie, M; Hamedani, R; Hamidieh, AA; Sadrai, S, 2010) |
| "4 ml/min/kg, with a terminal half-life of 10." | 1.28 | Lorazepam pharmacodynamics and pharmacokinetics in children. ( Dodge, RK; Evans, WE; Johnson, D; Mulhern, RK; Pieper, JA; Relling, MV; Rivera, GK, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ono, A | 1 |
| Kishimoto, K | 1 |
| Hasegawa, D | 1 |
| Goldman, RD | 1 |
| Kosaka, Y | 1 |
| Hamidieh, AA | 1 |
| Hamedani, R | 1 |
| Hadjibabaie, M | 1 |
| Amini, M | 1 |
| Sadrai, S | 1 |
| Ghavamzadeh, A | 1 |
| Relling, MV | 3 |
| Mulhern, RK | 2 |
| Fairclough, D | 1 |
| Baker, D | 1 |
| Pui, CH | 1 |
| Pelletier, G | 1 |
| Lacroix, Y | 1 |
| Moghrabi, A | 1 |
| Robaey, P | 1 |
| Crom, WR | 1 |
| Christensen, ML | 1 |
| Rivera, GK | 2 |
| Evans, WE | 2 |
| Dodge, RK | 1 |
| Johnson, D | 1 |
| Pieper, JA | 1 |
2 trials available for lorazepam and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
Chlorpromazine with and without lorazepam as antiemetic therapy in children receiving uniform chemotherapy.
Topics: Adolescent; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Ch | 1993 |
Double-blind crossover study of chlorpromazine and lorazepam in the treatment of behavioral problems during treatment of children with acute lymphoblastic leukaemia receiving glucocorticoids.
Topics: Anti-Anxiety Agents; Antipsychotic Agents; Child; Child Behavior; Child Behavior Disorders; Chlorpro | 2000 |
4 other studies available for lorazepam and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
Impact of adjuvant lorazepam with granisetron on chemotherapy-induced nausea and vomiting in pediatric patients with acute lymphoblastic leukemia.
Topics: Adjuvants, Pharmaceutic; Adolescent; Adrenal Cortex Hormones; Anthracyclines; Antiemetics; Antineopl | 2019 |
Oral lorazepam prevents seizure during high-dose busulfan in children undergoing hematopoietic stem cell transplantation: a prospective study.
Topics: Administration, Oral; Adolescent; Anticonvulsants; Busulfan; Child; Child, Preschool; Dose-Response | 2010 |
Age-related differences in hepatic drug clearance in children: studies with lorazepam and antipyrine.
Topics: Adolescent; Adult; Age Factors; Antipyrine; Body Weight; Child; Child, Preschool; Female; Humans; In | 1991 |
Lorazepam pharmacodynamics and pharmacokinetics in children.
Topics: Adolescent; Attention; Child; Child, Preschool; Emotions; Humans; Lorazepam; Memory; Metabolic Clear | 1989 |