Page last updated: 2024-10-30

lorazepam and Ache

lorazepam has been researched along with Ache in 28 studies

Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.

Research Excerpts

ExcerptRelevanceReference
"Eighty-seven per cent of surgical patients receiving undiluted diazepam experienced pain on injection while 6-16%, depending on the dose, manifested evidence of clinical thrombophlebitis."9.04Pain and clinical thrombophlebitis following intravenous diazepam and lorazepam. ( Conner, JT; Graham, CW; Pagano, RR, 1978)
"Pain was rated using a 10-cm linear visual analog scale (VAS)."6.73A randomized double-blind placebo-controlled study of low-dose intravenous Lorazepam to reduce procedural pain during bone marrow aspiration and biopsy. ( Ahn, JY; Bang, SM; Cho, EK; Lee, JH; Nam, E; Park, SH; Shin, DB, 2008)
"To compare pain and anxiety levels between two prophylactic treatment regimens, a combination of sublingual tramadol Hcl with oral lorazepam and oral diazepam only."5.15Prophylactic analgesia before percutaneous liver biopsy: a clinical comparative study. ( Baruch, Y; Eisenberg, E; Kramskay, R; Tansky, A; Veitsman, E, 2011)
") lorazepam and hydromorphone reduces pain and anxiety during BMBA."5.09A randomized, placebo-controlled study of outpatient premedication for bone marrow biopsy in adults with lymphoma. ( Habermann, TM; Inwards, DJ; Schroeder, G; Wilson, PR; Witzig, TE; Wolanskyj, AP, 2000)
"Eighty-seven per cent of surgical patients receiving undiluted diazepam experienced pain on injection while 6-16%, depending on the dose, manifested evidence of clinical thrombophlebitis."5.04Pain and clinical thrombophlebitis following intravenous diazepam and lorazepam. ( Conner, JT; Graham, CW; Pagano, RR, 1978)
" Indications for droperidol included agitation, 68 (86%); nausea/vomiting, 7 (9%); headache, 2 (3%); and other pain, 2 (3%)."3.76Droperidol use in pediatric emergency department patients. ( Sacchetti, A; Szwak, K, 2010)
" The case presentation illustrates the role of pregabalin in successful medical management of this chronic pain disorder, as well as the management of common psychiatric morbidities associated with this condition."3.74Pregabalin-induced remission in a 62-year-old woman with a 20-year history of vulvodynia. ( Jerome, L, 2007)
"Pain was rated using a 10-cm linear visual analog scale (VAS)."2.73A randomized double-blind placebo-controlled study of low-dose intravenous Lorazepam to reduce procedural pain during bone marrow aspiration and biopsy. ( Ahn, JY; Bang, SM; Cho, EK; Lee, JH; Nam, E; Park, SH; Shin, DB, 2008)
" A 30-year-old female elite athlete developed lormetazepam addiction after increasing her daily benzodiazepine dosage in an attempt to achieve better sleep and enhanced performances during training."1.51Benzodiazepine abuse among athletes: Pain relief or just a weapon against insomnia? A clinical case study. ( Lugoboni, F; Zamboni, L; Zandonai, T, 2019)
"Lorazepam was given most often because of anxiety and agitation, oxazepam to induce sleep and midazolam in five cases of terminal sedation."1.35[Indications and use of benzodiazepines in a palliative care unit]. ( Elsner, F; Krumm, N; Radbruch, L; Schroers, O; Stiel, S, 2008)
" Demographic data, time in ED, and dosage of each medication given were abstracted."1.35Inadequate provision of postintubation anxiolysis and analgesia in the ED. ( Bonomo, JB; Butler, AS; Lindsell, CJ; Venkat, A, 2008)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19905 (17.86)18.7374
1990's5 (17.86)18.2507
2000's12 (42.86)29.6817
2010's4 (14.29)24.3611
2020's2 (7.14)2.80

Authors

AuthorsStudies
Wiemann, B3
Mitchell, J3
Sarangarm, P3
Miskimins, R3
Tripathi, S1
Laksana, E1
McCrory, MC1
Hsu, S1
Zhou, AX1
Burkiewicz, K1
Ledbetter, DR1
Aczon, MD1
Shah, S1
Siegel, L1
Fainberg, N1
Morrow, KR1
Avesar, M1
Chandnani, HK1
Shah, J1
Pringle, C1
Winter, MC1
Zamboni, L1
Lugoboni, F1
Zandonai, T1
Stiel, S1
Krumm, N1
Schroers, O1
Radbruch, L1
Elsner, F1
Zeilhofer, HU1
Witschi, R1
Hösl, K1
Talamo, G1
Liao, J1
Bayerl, MG1
Claxton, DF1
Zangari, M1
Wowchuk, SM1
Wilson, EA1
Embleton, L1
Garcia, M1
Harlos, M1
Chochinov, HM1
Szwak, K1
Sacchetti, A1
Kramskay, R1
Tansky, A1
Eisenberg, E1
Veitsman, E1
Baruch, Y1
Wiebe, E1
Podhradsky, L1
Dijak, V1
Kunz, M1
Scholl, KE1
Schu, U1
Lautenbacher, S1
Reid, C1
Jerome, L1
Park, SH1
Bang, SM1
Nam, E1
Cho, EK1
Shin, DB1
Lee, JH1
Ahn, JY1
Bonomo, JB1
Butler, AS1
Lindsell, CJ1
Venkat, A1
McGowan, WA1
Dundee, JW1
Clarke, RS1
Howard, PJ1
Patterson, DR1
Ptacek, JT1
Carrougher, GJ1
Sharar, SR1
Kollarits, CR1
Jaweed, S1
Kollarits, FJ1
Larson, JS1
Lunn, JJ1
Dunlop, TJ1
Deen, C1
Lind, S1
Voyle, RJ1
Prichard, JG1
Nath, C1
Saxena, RC1
Gupta, MB1
Spiritus, A1
Huygens, M1
Callebaut, F1
Wolanskyj, AP1
Schroeder, G1
Wilson, PR1
Habermann, TM1
Inwards, DJ1
Witzig, TE1
Graham, CW1
Pagano, RR1
Conner, JT1
Lipp, M1
Daubländer, M1
Milligan, DW1
Howard, MR1
Judd, A1
Koike, K1
Yokoi, A1
Okabe, H1
Yagi, T1
Isomura, A1
Miyata, Y1
Gotoh, M1
Sugiura, M1
Rizzo, PA1
Pierelli, F1
Pozzessere, G1
Fattapposta, F1
Sanarelli, L1
Morocutti, C1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Double-blind, Randomized, Placebo-controlled Study on the Effect of Multimodal Analgesia on Pain With Insertion of Levonorgestrel-releasing Intrauterine System[NCT02799641]61 participants (Actual)Interventional2016-07-31Completed
An Evaluation of Hydrocodone/Acetaminophen for Pain Control in First Trimester Surgical Abortion[NCT01330459]Phase 4121 participants (Actual)Interventional2011-02-28Completed
Oral Sedation During Cervical Dilator Placement: A Randomized Controlled Trial[NCT03202550]Phase 427 participants (Actual)Interventional2017-06-28Completed
An Evaluation of the Paracervical Block for Pain Control in First Trimester Surgical Abortion[NCT01094366]Phase 4121 participants (Actual)Interventional2010-04-30Completed
Comparison of Three Different Pain and Anxiety Reducing Methods in Adult Patients Undergoing Bone Marrow Puncture[NCT00188227]Phase 4748 participants Interventional2001-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Need for Additional Intraoperative and/or Postoperative Pain Medication

To assess need for additional intraoperative and/or postoperative pain medication (NCT01330459)
Timeframe: 30 minutes after completion of the procedure (which started 45-90 minutes after study drug administration)

InterventionParticipants (Count of Participants)
Hydrocodone/Acetaminophen0
Placebo0

Patient Perception of Pain

To determine whether HC/APAP, given in addition to a standard regimen of ibuprofen, lorazepam, and PCB, affects patient pain perception at the time of uterine aspiration, as measured by distance (mm) from the left of the 100 mm visual analog scale (VAS). The number 0 indicates no pain, and 100 indicates worst pain imaginable. (NCT01330459)
Timeframe: At time of uterine aspiration (baseline)

Interventionmm (Mean)
Hydrocodone/Acetaminophen65.7
Placebo63.1

Patient Perception of Pain During Cervical Dilation

Distance (mm) from the left of the 100 mm VAS scale (VAS anchors: 0 = none, 100 mm = worst imaginable) recorded after cervical dilation (NCT01330459)
Timeframe: During procedure (approximately 45-90 min after hydrocodone/acetaminophen or placebo, and within 5 minutes of procedure starting)

Interventionmm (Mean)
Hydrocodone/Acetaminophen47.2
Placebo43.9

Postoperative Nausea

To assess whether HC/APAP is associated with nausea, measured on the 100 mm VAS, recorded 30 minutes postoperatively. VAS anchors: 0 indicates no pain, and 100 indicates worst pain imaginable. (NCT01330459)
Timeframe: 30 minutes after completion of the procedure (which started 45-90 minutes after study drug administration)

Interventionmm (Mean)
Hydrocodone/Acetaminophen19.4
Placebo11.4

Satisfaction With Pain Control

Distance (mm) from the left of the 100 mm VAS (VAS anchors: 0 = unsatisfied, 100 mm = very satisfied) recorded 30 minutes after completion of the procedure. (NCT01330459)
Timeframe: 30 minutes after completion of the procedure (which started 45-90 minutes after study drug administration)

Interventionmm (Mean)
Hydrocodone/Acetaminophen74.8
Placebo67.3

Baseline Pain Score Before Drugs Were Administered

Compare pain scores on a 100 mm visual analog scale (VAS) (anchors 0=no pain; 100=worst pain ever) (NCT03202550)
Timeframe: pain score given prior to administration of study drugs, up to 1 minute

Interventionunits on a scale (Median)
Placebo Arm3
Active Drug Arm: Lorazepam and Oxycodone2

Cervical Dilator Placement Pain as Assessed by VAS on a Tablet Device

Compare pain scores on a 100 mm visual analog scale (VAS) (anchors 0=no pain; 100=worst pain ever) (NCT03202550)
Timeframe: Immediately after the last dilator is placed, up to 1 minute

Interventionunits on a scale (Median)
Placebo Arm55
Active Drug Arm: Lorazepam and Oxycodone44

Number of Participants With Desired Number of Dilators Inserted

Assess whether desired number of dilators was not able to be successfully inserted, comparing 2 arms. (NCT03202550)
Timeframe: After speculum removed, up to 30 minutes

InterventionParticipants (Count of Participants)
Placebo Arm13
Active Drug Arm: Lorazepam and Oxycodone10

Pain Score 15 Minutes After Last Dilator Placed

Compare pain scores on a 100 mm visual analog scale (VAS) (anchors 0=no pain; 100=worst pain ever). This was to be assessed at 15 minutes after last dilator is placed. Some participants had this assessment done up to 45 minutes after last dilator was placed because it could not be done at 15 minutes (some were being attended to by a nurse at the 15 minutes mark). (NCT03202550)
Timeframe: Assessed up to 45 minutes after last dilator placed

Interventionunits on a scale (Median)
Placebo Arm29
Active Drug Arm: Lorazepam and Oxycodone13

Pain Score After First Dilator Placement

Compare pain scores on a 100 mm visual analog scale (VAS) (anchors 0=no pain; 100=worst pain ever) (NCT03202550)
Timeframe: pain score given immediately after first dilator placed, up to 1 minute

Interventionunits on a scale (Median)
Placebo Arm50
Active Drug Arm: Lorazepam and Oxycodone9

Pain Score After Speculum Placement

Compare pain scores on a 100 mm visual analog scale (VAS) (anchors 0=no pain; 100=worst pain ever) (NCT03202550)
Timeframe: pain score given at time of speculum placement, up to 1 minute

Interventionunits on a scale (Median)
Placebo Arm20
Active Drug Arm: Lorazepam and Oxycodone11

Pain Score at Tenaculum Placement

Compare pain scores on a 100 mm visual analog scale (VAS) (anchors 0=no pain; 100=worst pain ever) (NCT03202550)
Timeframe: Immediately scored at time of tenacula placement, up to 1 minute

Interventionunits on a scale (Median)
Placebo Arm31
Active Drug Arm: Lorazepam and Oxycodone50

Pain Score Before Speculum Placement

Compare pain scores on a 100 mm visual analog scale (VAS) (anchors 0=no pain; 100=worst pain ever) (NCT03202550)
Timeframe: pain score given before specula placed, up to 1 minute

Interventionunits on a scale (Median)
Placebo Arm1
Active Drug Arm: Lorazepam and Oxycodone1

Pain Score During Paracervical Block

Compare pain scores on a 100 mm visual analog scale (VAS) (anchors 0=no pain; 100=worst pain ever) (NCT03202550)
Timeframe: pain score given at time of paracervical block administration, up to 1 minute

Interventionunits on a scale (Median)
Placebo Arm57
Active Drug Arm: Lorazepam and Oxycodone51

Reviews

2 reviews available for lorazepam and Ache

ArticleYear
Subtype-selective GABAA receptor mimetics--novel antihyperalgesic agents?
    Journal of molecular medicine (Berlin, Germany), 2009, Volume: 87, Issue:5

    Topics: Analgesics; Animals; Benzodiazepines; Brain; GABA Agonists; GABA-A Receptor Agonists; Humans; Loraze

2009
Comparing drugs for short-term sedation.
    Contemporary internal medicine, 1994, Volume: 6, Issue:12

    Topics: Anesthesia; Benzodiazepines; Conscious Sedation; Diazepam; Flumazenil; Humans; Lorazepam; Midazolam;

1994

Trials

12 trials available for lorazepam and Ache

ArticleYear
Oral administration of analgesia and anxiolysis for pain associated with bone marrow biopsy.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2010, Volume: 18, Issue:3

    Topics: Acetaminophen; Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics; Anesthesia, Local;

2010
Prophylactic analgesia before percutaneous liver biopsy: a clinical comparative study.
    European journal of gastroenterology & hepatology, 2011, Volume: 23, Issue:9

    Topics: Adult; Analgesia; Analgesics, Opioid; Anti-Anxiety Agents; Anxiety; Biopsy, Needle; Diazepam; Female

2011
The effect of lorazepam on pain and anxiety in abortion.
    Contraception, 2003, Volume: 67, Issue:3

    Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep

2003
The effect of lorazepam on pain and anxiety in abortion.
    Contraception, 2003, Volume: 67, Issue:3

    Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep

2003
The effect of lorazepam on pain and anxiety in abortion.
    Contraception, 2003, Volume: 67, Issue:3

    Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep

2003
The effect of lorazepam on pain and anxiety in abortion.
    Contraception, 2003, Volume: 67, Issue:3

    Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep

2003
The effect of lorazepam on pain and anxiety in abortion.
    Contraception, 2003, Volume: 67, Issue:3

    Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep

2003
The effect of lorazepam on pain and anxiety in abortion.
    Contraception, 2003, Volume: 67, Issue:3

    Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep

2003
The effect of lorazepam on pain and anxiety in abortion.
    Contraception, 2003, Volume: 67, Issue:3

    Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep

2003
The effect of lorazepam on pain and anxiety in abortion.
    Contraception, 2003, Volume: 67, Issue:3

    Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep

2003
The effect of lorazepam on pain and anxiety in abortion.
    Contraception, 2003, Volume: 67, Issue:3

    Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep

2003
The effect of lorazepam on pain and anxiety in abortion.
    Contraception, 2003, Volume: 67, Issue:3

    Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep

2003
The effect of lorazepam on pain and anxiety in abortion.
    Contraception, 2003, Volume: 67, Issue:3

    Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep

2003
The effect of lorazepam on pain and anxiety in abortion.
    Contraception, 2003, Volume: 67, Issue:3

    Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep

2003
The effect of lorazepam on pain and anxiety in abortion.
    Contraception, 2003, Volume: 67, Issue:3

    Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep

2003
The effect of lorazepam on pain and anxiety in abortion.
    Contraception, 2003, Volume: 67, Issue:3

    Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep

2003
The effect of lorazepam on pain and anxiety in abortion.
    Contraception, 2003, Volume: 67, Issue:3

    Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep

2003
The effect of lorazepam on pain and anxiety in abortion.
    Contraception, 2003, Volume: 67, Issue:3

    Topics: Abortion, Induced; Adult; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Lorazep

2003
GABAergic modulation of diffuse noxious inhibitory controls (DNIC): a test by use of lorazepam.
    Experimental brain research, 2006, Volume: 175, Issue:2

    Topics: Adult; Double-Blind Method; Female; GABA Modulators; Hot Temperature; Humans; Lorazepam; Male; Neura

2006
A randomized double-blind placebo-controlled study of low-dose intravenous Lorazepam to reduce procedural pain during bone marrow aspiration and biopsy.
    Pain medicine (Malden, Mass.), 2008, Volume: 9, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Biopsy, Needle; Bone Marrow; Double-Blind Method; Fema

2008
Comparison of the subjective effects and plasma concentrations following oral and i.m. administration of flunitrazepam in patients.
    British journal of anaesthesia, 1980, Volume: 52, Issue:4

    Topics: Administration, Oral; Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Diazepam; Double-Blind M

1980
Lorazepam as an adjunct to opioid analgesics in the treatment of burn pain.
    Pain, 1997, Volume: 72, Issue:3

    Topics: Adult; Analgesics, Opioid; Anti-Anxiety Agents; Anxiety; Burns; Drug Therapy, Combination; Female; H

1997
Use of combined oral narcotic and benzodiazepine for control of pain associated with bone marrow examination.
    Southern medical journal, 1999, Volume: 92, Issue:5

    Topics: Administration, Oral; Adult; Analgesia; Benzodiazepines; Bone Marrow Examination; Drug Therapy, Comb

1999
Topical anesthesia without intracameral lidocaine in cataract surgery.
    Bulletin de la Societe belge d'ophtalmologie, 2000, Volume: 275

    Topics: Aged; Aged, 80 and over; Anesthetics, Local; Blepharospasm; Cataract Extraction; Humans; Hypnotics a

2000
A randomized, placebo-controlled study of outpatient premedication for bone marrow biopsy in adults with lymphoma.
    Clinical lymphoma, 2000, Volume: 1, Issue:2

    Topics: Administration, Oral; Adult; Aged; Ambulatory Care; Analgesics, Opioid; Anti-Anxiety Agents; Anxiety

2000
Pain and clinical thrombophlebitis following intravenous diazepam and lorazepam.
    Anaesthesia, 1978, Volume: 33, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Clinical Trials as Topic; Diazepam; Double-Blind Metho

1978
Premedication with lorazepam before bone marrow biopsy.
    Journal of clinical pathology, 1987, Volume: 40, Issue:6

    Topics: Adolescent; Adult; Aged; Biopsy, Needle; Bone Marrow Examination; Double-Blind Method; Female; Human

1987

Other Studies

14 other studies available for lorazepam and Ache

ArticleYear
Tracheotomy in ventilator-dependent patients with COVID-19: a cross-sectional study of analgesia and sedative requirements.
    The Journal of international medical research, 2022, Volume: 50, Issue:11

    Topics: Analgesia; Analgesics; COVID-19; Cross-Sectional Studies; Dexmedetomidine; Humans; Hypnotics and Sed

2022
Tracheotomy in ventilator-dependent patients with COVID-19: a cross-sectional study of analgesia and sedative requirements.
    The Journal of international medical research, 2022, Volume: 50, Issue:11

    Topics: Analgesia; Analgesics; COVID-19; Cross-Sectional Studies; Dexmedetomidine; Humans; Hypnotics and Sed

2022
Tracheotomy in ventilator-dependent patients with COVID-19: a cross-sectional study of analgesia and sedative requirements.
    The Journal of international medical research, 2022, Volume: 50, Issue:11

    Topics: Analgesia; Analgesics; COVID-19; Cross-Sectional Studies; Dexmedetomidine; Humans; Hypnotics and Sed

2022
Tracheotomy in ventilator-dependent patients with COVID-19: a cross-sectional study of analgesia and sedative requirements.
    The Journal of international medical research, 2022, Volume: 50, Issue:11

    Topics: Analgesia; Analgesics; COVID-19; Cross-Sectional Studies; Dexmedetomidine; Humans; Hypnotics and Sed

2022
Tracheotomy in ventilator-dependent patients with COVID-19: a cross-sectional study of analgesia and sedative requirements.
    The Journal of international medical research, 2022, Volume: 50, Issue:11

    Topics: Analgesia; Analgesics; COVID-19; Cross-Sectional Studies; Dexmedetomidine; Humans; Hypnotics and Sed

2022
Tracheotomy in ventilator-dependent patients with COVID-19: a cross-sectional study of analgesia and sedative requirements.
    The Journal of international medical research, 2022, Volume: 50, Issue:11

    Topics: Analgesia; Analgesics; COVID-19; Cross-Sectional Studies; Dexmedetomidine; Humans; Hypnotics and Sed

2022
Tracheotomy in ventilator-dependent patients with COVID-19: a cross-sectional study of analgesia and sedative requirements.
    The Journal of international medical research, 2022, Volume: 50, Issue:11

    Topics: Analgesia; Analgesics; COVID-19; Cross-Sectional Studies; Dexmedetomidine; Humans; Hypnotics and Sed

2022
Tracheotomy in ventilator-dependent patients with COVID-19: a cross-sectional study of analgesia and sedative requirements.
    The Journal of international medical research, 2022, Volume: 50, Issue:11

    Topics: Analgesia; Analgesics; COVID-19; Cross-Sectional Studies; Dexmedetomidine; Humans; Hypnotics and Sed

2022
Tracheotomy in ventilator-dependent patients with COVID-19: a cross-sectional study of analgesia and sedative requirements.
    The Journal of international medical research, 2022, Volume: 50, Issue:11

    Topics: Analgesia; Analgesics; COVID-19; Cross-Sectional Studies; Dexmedetomidine; Humans; Hypnotics and Sed

2022
Analgesia and Sedation at Terminal Extubation: A Secondary Analysis From Death One Hour After Terminal Extubation Study Data.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2023, 06-01, Volume: 24, Issue:6

    Topics: Airway Extubation; Analgesia; Analgesics, Opioid; Benzodiazepines; Child; Child, Preschool; Humans;

2023
Benzodiazepine abuse among athletes: Pain relief or just a weapon against insomnia? A clinical case study.
    Scandinavian journal of medicine & science in sports, 2019, Volume: 29, Issue:12

    Topics: Adult; Athletes; Female; Humans; Lorazepam; Pain; Pain Management; Sleep; Sleep Initiation and Maint

2019
[Indications and use of benzodiazepines in a palliative care unit].
    Schmerz (Berlin, Germany), 2008, Volume: 22, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Benzodiazepines; Female; Humans; Lorazepam; Male; Middle Aged; Neopl

2008
The palliative medication kit: an effective way of extending care in the home for patients nearing death.
    Journal of palliative medicine, 2009, Volume: 12, Issue:9

    Topics: Aged; Analgesics, Opioid; Benzodiazepines; Female; Home Care Services; Humans; Hypnotics and Sedativ

2009
Droperidol use in pediatric emergency department patients.
    Pediatric emergency care, 2010, Volume: 26, Issue:4

    Topics: Adjuvants, Anesthesia; Adolescent; Anti-Anxiety Agents; Antiemetics; Central Nervous System Depressa

2010
Medicating "Margaret".
    The Journal of clinical ethics, 2006,Winter, Volume: 17, Issue:4

    Topics: Advance Directives; Alzheimer Disease; Analgesics, Opioid; Antipsychotic Agents; Electroconvulsive T

2006
Pregabalin-induced remission in a 62-year-old woman with a 20-year history of vulvodynia.
    Pain research & management, 2007,Autumn, Volume: 12, Issue:3

    Topics: Amitriptyline; Analgesics; Anti-Ulcer Agents; Anticoagulants; Antidepressive Agents; Anxiety; Cardio

2007
Inadequate provision of postintubation anxiolysis and analgesia in the ED.
    The American journal of emergency medicine, 2008, Volume: 26, Issue:4

    Topics: Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Anxiety; Cohort Studies; Emergency Service, Ho

2008
Comparison of pain, motility, and preoperative sedation in cataract phacoemulsification patients receiving peribulbar or sub-Tenon's anesthesia.
    Ophthalmic surgery and lasers, 1998, Volume: 29, Issue:6

    Topics: Anesthesia, Local; Anesthetics, Local; Diazepam; Eye Movements; Follow-Up Studies; Humans; Hypnotics

1998
Effect of dopamine agonists and antagonists on the lorazepam withdrawal syndrome in rats.
    Clinical and experimental pharmacology & physiology, 2000, Volume: 27, Issue:3

    Topics: Acoustic Stimulation; Aggression; Animals; Anti-Anxiety Agents; Dopamine Agonists; Dopamine Antagoni

2000
[Premedication and analgesic dose procedures in dental medicine].
    Zahnarztliche Praxis, 1991, Jul-12, Volume: 42, Issue:7

    Topics: Anesthesia, Dental; Anesthesia, Local; Buprenorphine; Clorazepate Dipotassium; Diazepam; Flunitrazep

1991
The suppressive effect of autogenic training against pain stimulus on oral mucosa.
    The Journal of Nihon University School of Dentistry, 1985, Volume: 27, Issue:3

    Topics: Autogenic Training; Heart Rate; Humans; Injections; Lorazepam; Male; Mouth Mucosa; Pain; Pulse

1985
Pain, anxiety, and contingent negative variation: a clinical and pharmacological study.
    Biological psychiatry, 1985, Volume: 20, Issue:12

    Topics: Adult; Anxiety; Contingent Negative Variation; Electrophysiology; Female; Humans; Lorazepam; Male; M

1985