loratadine has been researched along with Uremia in 2 studies
Loratadine: A second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS) it lacks central nervous system depressing effects such as drowsiness.
loratadine : A benzocycloheptapyridine that is 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine substituted by a chloro group at position 8 and a 1-(ethoxycarbonyl)piperidin-4-ylidene group at position 11. It is a H1-receptor antagonist commonly employed in the treatment of allergic disorders.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the efficacy and side effects of gabapentin and desloratadine in patients with dialysis pruritus." | 9.16 | Uremic pruritus in hemodialysis patients: treatment with desloratidine versus gabapentin. ( Barrón, B; Lauxmann, JE; Marquez, D; Martinatto, C; Novoa, PA; Orías, M; Peixoto, AJ; Ramonda, C; Romero, CA; Vukelic, VL, 2012) |
| "To compare the efficacy and tolerance of naltrexone and loratadine in uremic pruritus." | 9.11 | A comparative study on the effects of naltrexone and loratadine on uremic pruritus. ( Clèdes, J; Legroux-Crespel, E; Misery, L, 2004) |
| "To compare the efficacy and side effects of gabapentin and desloratadine in patients with dialysis pruritus." | 5.16 | Uremic pruritus in hemodialysis patients: treatment with desloratidine versus gabapentin. ( Barrón, B; Lauxmann, JE; Marquez, D; Martinatto, C; Novoa, PA; Orías, M; Peixoto, AJ; Ramonda, C; Romero, CA; Vukelic, VL, 2012) |
| "To compare the efficacy and tolerance of naltrexone and loratadine in uremic pruritus." | 5.11 | A comparative study on the effects of naltrexone and loratadine on uremic pruritus. ( Clèdes, J; Legroux-Crespel, E; Misery, L, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marquez, D | 1 |
| Ramonda, C | 1 |
| Lauxmann, JE | 1 |
| Romero, CA | 1 |
| Vukelic, VL | 1 |
| Martinatto, C | 1 |
| Barrón, B | 1 |
| Novoa, PA | 1 |
| Peixoto, AJ | 1 |
| Orías, M | 1 |
| Legroux-Crespel, E | 1 |
| Clèdes, J | 1 |
| Misery, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Aprepitant vs. Desloratadine in Non-small Cell Lung Cancer Patients With Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors Related Pruritus: A Prospective, Randomized Control, Double-blinded, Phase II Clinical Trial[NCT02646020] | Phase 2 | 138 participants (Actual) | Interventional | 2015-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for loratadine and Uremia
| Article | Year |
|---|---|
Uremic pruritus in hemodialysis patients: treatment with desloratidine versus gabapentin.
Topics: Amines; Cross-Over Studies; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Histam | 2012 |
A comparative study on the effects of naltrexone and loratadine on uremic pruritus.
Topics: Antipruritics; Drug Administration Schedule; Female; Humans; Loratadine; Male; Middle Aged; Naltrexo | 2004 |