loratadine has been researched along with Sleepiness in 2 studies
Loratadine: A second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS) it lacks central nervous system depressing effects such as drowsiness.
loratadine : A benzocycloheptapyridine that is 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine substituted by a chloro group at position 8 and a 1-(ethoxycarbonyl)piperidin-4-ylidene group at position 11. It is a H1-receptor antagonist commonly employed in the treatment of allergic disorders.
Sleepiness: Compelling urge to sleep.
| Excerpt | Relevance | Reference |
|---|---|---|
| "H1 nonsedating antihistamines, such as desloratadine, are first-line treatment options for chronic spontaneous urticaria (CSU)." | 5.34 | Human H1 receptor (HRH1) gene polymorphism is associated with the severity of side effects after desloratadine treatment in Chinese patients with chronic spontaneous uticaria. ( Chen, W; Chen, X; Li, J; Liu, Z; Peng, C; Su, J; Zhang, W; Zhu, W, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, J | 2 |
| Chen, W | 1 |
| Peng, C | 1 |
| Zhu, W | 1 |
| Liu, Z | 1 |
| Zhang, W | 1 |
| Su, J | 1 |
| Chen, X | 1 |
| Nakamura, T | 1 |
| Hiraoka, K | 1 |
| Harada, R | 1 |
| Matsuzawa, T | 1 |
| Ishikawa, Y | 1 |
| Funaki, Y | 1 |
| Yoshikawa, T | 1 |
| Tashiro, M | 1 |
| Yanai, K | 1 |
| Okamura, N | 1 |
2 trials available for loratadine and Sleepiness
| Article | Year |
|---|---|
Human H1 receptor (HRH1) gene polymorphism is associated with the severity of side effects after desloratadine treatment in Chinese patients with chronic spontaneous uticaria.
Topics: Adult; China; Chronic Disease; Drug-Related Side Effects and Adverse Reactions; Female; Histamine H1 | 2020 |
Brain histamine H
Topics: Adult; Brain; Cross-Over Studies; Double-Blind Method; Healthy Volunteers; Histamine H1 Antagonists, | 2019 |