Page last updated: 2024-10-30

loratadine and Liver Diseases

loratadine has been researched along with Liver Diseases in 3 studies

Loratadine: A second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS) it lacks central nervous system depressing effects such as drowsiness.
loratadine : A benzocycloheptapyridine that is 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine substituted by a chloro group at position 8 and a 1-(ethoxycarbonyl)piperidin-4-ylidene group at position 11. It is a H1-receptor antagonist commonly employed in the treatment of allergic disorders.

Liver Diseases: Pathological processes of the LIVER.

Research Excerpts

ExcerptRelevanceReference
" Eleven treatment-related adverse events, all mild to moderate in severity, were reported."2.73Multiple-dose pharmacokinetics and safety of desloratadine in subjects with moderate hepatic impairment. ( Gupta, SK; Kantesaria, B; Wang, Z, 2007)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gupta, SK1
Kantesaria, B1
Wang, Z1
Najarian, JS1
Clark, S1

Trials

1 trial available for loratadine and Liver Diseases

ArticleYear
Multiple-dose pharmacokinetics and safety of desloratadine in subjects with moderate hepatic impairment.
    Journal of clinical pharmacology, 2007, Volume: 47, Issue:10

    Topics: Adult; Aged; Analysis of Variance; Area Under Curve; Female; Half-Life; Histamine H1 Antagonists, No

2007

Other Studies

2 other studies available for loratadine and Liver Diseases

ArticleYear
Hepatic necrosis.
    New Jersey medicine : the journal of the Medical Society of New Jersey, 1996, Volume: 93, Issue:1

    Topics: Chemical and Drug Induced Liver Injury; Female; Humans; Liver Diseases; Loratadine; Middle Aged; Nec

1996
Dangers of non-sedating antihistamines.
    Lancet (London, England), 1997, May-03, Volume: 349, Issue:9061

    Topics: Arrhythmias, Cardiac; Astemizole; Cetirizine; Heart Diseases; Histamine H1 Antagonists; Humans; Legi

1997