loratadine has been researched along with Hypospadias in 5 studies
Loratadine: A second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS) it lacks central nervous system depressing effects such as drowsiness.
loratadine : A benzocycloheptapyridine that is 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine substituted by a chloro group at position 8 and a 1-(ethoxycarbonyl)piperidin-4-ylidene group at position 11. It is a H1-receptor antagonist commonly employed in the treatment of allergic disorders.
Hypospadias: A birth defect due to malformation of the URETHRA in which the urethral opening is below its normal location. In the male, the malformed urethra generally opens on the ventral surface of the PENIS or on the PERINEUM. In the female, the malformed urethral opening is in the VAGINA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This meta-analysis was designed to assess the strength of the association between loratadine and hypospadias." | 8.84 | Risk of hypospadias in offspring of women using loratadine during pregnancy: a systematic review and meta-analysis. ( Koren, G; Moretti, ME; Nayak, S; Schwarz, EB, 2008) |
| "Hypospadias is a birth defect that affects approximately seven in 1,000 male infants in the United States." | 5.32 | Evaluation of an association between loratadine and hypospadias--United States, 1997-2001. ( , 2004) |
| "This meta-analysis was designed to assess the strength of the association between loratadine and hypospadias." | 4.84 | Risk of hypospadias in offspring of women using loratadine during pregnancy: a systematic review and meta-analysis. ( Koren, G; Moretti, ME; Nayak, S; Schwarz, EB, 2008) |
| "Hypospadias is a birth defect that affects approximately seven in 1,000 male infants in the United States." | 1.32 | Evaluation of an association between loratadine and hypospadias--United States, 1997-2001. ( , 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schwarz, EB | 1 |
| Moretti, ME | 1 |
| Nayak, S | 1 |
| Koren, G | 1 |
| Kallen, B | 1 |
| Pedersen, L | 1 |
| Nørgaard, M | 1 |
| Rothman, KJ | 1 |
| Sørensen, HT | 1 |
1 review available for loratadine and Hypospadias
| Article | Year |
|---|---|
Risk of hypospadias in offspring of women using loratadine during pregnancy: a systematic review and meta-analysis.
Topics: Abnormalities, Drug-Induced; Anti-Allergic Agents; Female; Humans; Hypospadias; Loratadine; Male; Mo | 2008 |
4 other studies available for loratadine and Hypospadias
| Article | Year |
|---|---|
Loratadine, desloratadine and pregnancy: don't use, risk of hypospadias.
Topics: Contraindications; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Hypospadias; Loratadine; | 2003 |
Evaluation of an association between loratadine and hypospadias--United States, 1997-2001.
Topics: Abnormalities, Drug-Induced; Anti-Allergic Agents; Humans; Hypospadias; Infant, Newborn; Loratadine; | 2004 |
Effect of perinatal (prenatal?) loratadine exposure on male rat reproductive organ development.
Topics: Animals; Anti-Allergic Agents; Genitalia, Male; Humans; Hypospadias; Loratadine; Male; Population Su | 2004 |
Loratadine during pregnancy and hypospadias.
Topics: Abnormalities, Drug-Induced; Anti-Allergic Agents; Case-Control Studies; Denmark; Female; Humans; Hy | 2008 |