loratadine has been researched along with Eye Disorders in 2 studies
Loratadine: A second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS) it lacks central nervous system depressing effects such as drowsiness.
loratadine : A benzocycloheptapyridine that is 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine substituted by a chloro group at position 8 and a 1-(ethoxycarbonyl)piperidin-4-ylidene group at position 11. It is a H1-receptor antagonist commonly employed in the treatment of allergic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Desloratadine was significantly more effective than placebo in preventing post-challenge ocular pruritus (P<0." | 2.74 | Evaluation of desloratadine on conjunctival allergen challenge-induced ocular symptoms. ( Gomes, P; Gopalan, G; Srinivasan, S; Torkildsen, GL; Welch, D, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Torkildsen, GL | 1 |
| Gomes, P | 1 |
| Welch, D | 1 |
| Gopalan, G | 1 |
| Srinivasan, S | 1 |
| Horak, F | 1 |
| Toth, J | 1 |
| Hirschwehr, R | 1 |
| Marks, B | 1 |
| Stübner, UP | 1 |
| Jäger, S | 1 |
| Berger, U | 1 |
| Schleinzer, K | 1 |
| Günczler, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Double-blind, Placebo-controlled, Crossover, Single-center Study to Evaluate the Anti-allergic and Anti-inflammatory Effects of Multiple Doses of Desloratadine on Conjunctival Allergen Challenge-induced Ocular Signs and Symptoms[NCT00311844] | Phase 4 | 41 participants (Actual) | Interventional | 2005-03-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for loratadine and Eye Disorders
| Article | Year |
|---|---|
Evaluation of desloratadine on conjunctival allergen challenge-induced ocular symptoms.
Topics: Administration, Oral; Adult; Aged; Conjunctivitis, Allergic; Cross-Over Studies; Dose-Response Relat | 2009 |
Effect of continuous allergen challenge on clinical symptoms and mediator release in dust-mite-allergic patients.
Topics: Adult; Antigens, Dermatophagoides; Blood Proteins; Bronchial Provocation Tests; Chymases; Cross-Over | 1998 |