loratadine has been researched along with Electrocardiogram QT Prolonged in 5 studies
Loratadine: A second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS) it lacks central nervous system depressing effects such as drowsiness.
loratadine : A benzocycloheptapyridine that is 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine substituted by a chloro group at position 8 and a 1-(ethoxycarbonyl)piperidin-4-ylidene group at position 11. It is a H1-receptor antagonist commonly employed in the treatment of allergic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cetirizine is a metabolite of hydroxyzine, another antihistamine." | 2.46 | Cetirizine and loratadine: minimal risk of QT prolongation. ( , 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cavalli, A | 1 |
| Poluzzi, E | 1 |
| De Ponti, F | 1 |
| Recanatini, M | 1 |
| Atar, S | 1 |
| Freedberg, NA | 1 |
| Antonelli, D | 1 |
| Rosenfeld, T | 1 |
| Lehman, JM | 1 |
| Blaiss, MS | 1 |
| Henderson, W | 1 |
| Chu, J | 1 |
| Hoffman, R | 1 |
2 reviews available for loratadine and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
Cetirizine and loratadine: minimal risk of QT prolongation.
Topics: Anti-Allergic Agents; Cetirizine; Drug Interactions; Histamine H1 Antagonists, Non-Sedating; Humans; | 2010 |
Selecting the optimal oral antihistamine for patients with allergic rhinitis.
Topics: Administration, Oral; Cardiovascular System; Central Nervous System; Cetirizine; Drug Interactions; | 2006 |
3 other studies available for loratadine and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go- | 2002 |
Torsades de pointes and QT prolongation due to a combination of loratadine and amiodarone.
Topics: Aged; Amiodarone; Anti-Allergic Agents; Anti-Arrhythmia Agents; Electrocardiography; Female; Humans; | 2003 |
QTc prolongation and drugs.
Topics: Antidepressive Agents, Second-Generation; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Cyt | 2001 |