loratadine has been researched along with Dry Eye Syndromes in 2 studies
Loratadine: A second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS) it lacks central nervous system depressing effects such as drowsiness.
loratadine : A benzocycloheptapyridine that is 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine substituted by a chloro group at position 8 and a 1-(ethoxycarbonyl)piperidin-4-ylidene group at position 11. It is a H1-receptor antagonist commonly employed in the treatment of allergic disorders.
Dry Eye Syndromes: Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Loratadine was shown to induce 93% greater conjunctival staining after 4 days of use and CAE exposure vs cetirizine hydrochloride (P = ." | 2.71 | An evaluation of the ocular drying effects of 2 systemic antihistamines: loratadine and cetirizine hydrochloride. ( Abelson, MB; Gupta, G; Ousler, GW; Wilcox, KA, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Welch, D | 1 |
| Ousler, GW | 2 |
| Nally, LA | 1 |
| Abelson, MB | 2 |
| Wilcox, KA | 2 |
| Gupta, G | 1 |
2 trials available for loratadine and Dry Eye Syndromes
| Article | Year |
|---|---|
Ocular drying associated with oral antihistamines (loratadine) in the normal population-an evaluation of exaggerated dose effect.
Topics: Adaptation, Physiological; Administration, Oral; Conjunctiva; Dose-Response Relationship, Drug; Drug | 2002 |
An evaluation of the ocular drying effects of 2 systemic antihistamines: loratadine and cetirizine hydrochloride.
Topics: Adult; Aged; Cetirizine; Double-Blind Method; Dry Eye Syndromes; Female; Histamine H1 Antagonists, N | 2004 |