loratadine has been researched along with Daytime Sleepiness in 3 studies
Loratadine: A second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS) it lacks central nervous system depressing effects such as drowsiness.
loratadine : A benzocycloheptapyridine that is 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine substituted by a chloro group at position 8 and a 1-(ethoxycarbonyl)piperidin-4-ylidene group at position 11. It is a H1-receptor antagonist commonly employed in the treatment of allergic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Loratadine was significantly superior to placebo in 3 of 10 trials (30%), consistent with rates found in 3 pivotal group trials used for FDA approval (24%, 17%, and 0%)." | 2.70 | Single-patient drug trial methodology for allergic rhinitis. ( Del Rio, E; Rebell, G; Reitberg, DP; Weiss, SL; Zaias, N, 2002) |
| " Somnolence scores were similar for both groups at baseline and at the time of dosing (8:00 AM)." | 2.69 | Loratadine versus cetirizine: assessment of somnolence and motivation during the workday. ( Gates, D; Greiding, L; Heithoff, K; Ramon, F; Salmun, LM; Scharf, M, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reitberg, DP | 1 |
| Del Rio, E | 1 |
| Weiss, SL | 1 |
| Rebell, G | 1 |
| Zaias, N | 1 |
| Salmun, LM | 1 |
| Gates, D | 1 |
| Scharf, M | 1 |
| Greiding, L | 1 |
| Ramon, F | 1 |
| Heithoff, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prescription Methods Assessment Project (PMAP)[NCT00393653] | 800 participants (Anticipated) | Interventional | 2006-10-31 | Terminated (stopped due to Funding ended early) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for loratadine and Daytime Sleepiness
| Article | Year |
|---|---|
Single-patient drug trial methodology for allergic rhinitis.
Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Child; Chlorpheniramine; Clinical Trials as Topic; Da | 2002 |
Loratadine versus cetirizine: assessment of somnolence and motivation during the workday.
Topics: Adult; Anti-Allergic Agents; Cetirizine; Disorders of Excessive Somnolence; Double-Blind Method; Eff | 2000 |
1 other study available for loratadine and Daytime Sleepiness
| Article | Year |
|---|---|
Desloratadine (Clarinex).
Topics: Administration, Oral; Adolescent; Adult; Aged; Asthma; Controlled Clinical Trials as Topic; Disorder | 2002 |