loratadine has been researched along with Conjunctivitis, Allergic in 24 studies
Loratadine: A second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS) it lacks central nervous system depressing effects such as drowsiness.
loratadine : A benzocycloheptapyridine that is 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine substituted by a chloro group at position 8 and a 1-(ethoxycarbonyl)piperidin-4-ylidene group at position 11. It is a H1-receptor antagonist commonly employed in the treatment of allergic disorders.
Conjunctivitis, Allergic: Conjunctivitis due to hypersensitivity to various allergens.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These healthy adult volunteers with a history of seasonal allergic conjunctivitis had no clinical signs of ocular drying after 4 days of twice-daily treatment with topical epinastine." | 9.12 | An open-label, investigator-masked, crossover study of the ocular drying effects of two antihistamines, topical epinastine and systemic loratadine, in adult volunteers with seasonal allergic conjunctivitis. ( Ousler, GW; Torkildsen, GL; Workman, DA, 2007) |
| "To compare the efficacy of olopatadine used adjunctively with loratadine versus loratadine alone in patients with seasonal allergic conjunctivitis." | 9.09 | Olopatadine ophthalmic solution adjunctive to loratadine compared with loratadine alone in patients with active seasonal allergic conjunctivitis symptoms. ( Cockrum, PC; Gross, RD; Juniper, EF; Lanier, BQ; Marks, BB, 2001) |
| "These healthy adult volunteers with a history of seasonal allergic conjunctivitis had no clinical signs of ocular drying after 4 days of twice-daily treatment with topical epinastine." | 5.12 | An open-label, investigator-masked, crossover study of the ocular drying effects of two antihistamines, topical epinastine and systemic loratadine, in adult volunteers with seasonal allergic conjunctivitis. ( Ousler, GW; Torkildsen, GL; Workman, DA, 2007) |
| "Ketotifen fumarate is a topical antiallergic combination mast-cell stabilizer and antihistamine indicated for the temporary prevention of ocular itching due to allergic conjunctivitis." | 5.10 | Comparison of ketotifen fumarate ophthalmic solution alone, desloratadine alone, and their combination for inhibition of the signs and symptoms of seasonal allergic rhinoconjunctivitis in the conjunctival allergen challenge model: a double-masked, placebo ( Crampton, HJ, 2003) |
| "To determine whether Patanol in combination with the systemic antihistamine Claritin (loratadine, Schering, Kenilworth, NJ) reduces the ocular itching associated with allergic conjunctivitis more effectively than Claritin alone." | 5.09 | The added benefit of local Patanol therapy when combined with systemic Claritin for the inhibition of ocular itching in the conjunctival antigen challenge model. ( Abelson, MB; Lanier, RQ, 1999) |
| "To compare the efficacy of olopatadine used adjunctively with loratadine versus loratadine alone in patients with seasonal allergic conjunctivitis." | 5.09 | Olopatadine ophthalmic solution adjunctive to loratadine compared with loratadine alone in patients with active seasonal allergic conjunctivitis symptoms. ( Cockrum, PC; Gross, RD; Juniper, EF; Lanier, BQ; Marks, BB, 2001) |
| "Desloratadine was significantly more effective than placebo in preventing post-challenge ocular pruritus (P<0." | 2.74 | Evaluation of desloratadine on conjunctival allergen challenge-induced ocular symptoms. ( Gomes, P; Gopalan, G; Srinivasan, S; Torkildsen, GL; Welch, D, 2009) |
| " Recommended dosage of loratadine (CAS 79794-75-5) is 10 mg once daily, whereas terfenadine (CAS 50679-08-8) until recently has been recommended as 60 mg twice daily." | 2.67 | Comparison of loratadine and terfenadine in allergic seasonal rhinoconjunctivitis with emphasis on nasal stuffiness and peak flow. ( Hindberg Rasmussen, W; Høi, L; Lorentzen, KA; Nüchel Petersen, L; Olsen, OT; Svendsen, UG, 1992) |
| "Pretreatment with Loratadine resulted in a significant higher allergen threshold dose than placebo (p less than 0." | 2.67 | Protective effect of loratadine on specific conjunctival provocation test. ( Buscaglia, S; Canonica, GW; Ciprandi, G; Marchesi, E; Pesce, GP, 1991) |
| "Histamine is a key mediator of the allergic immediate reaction." | 2.43 | [Oral second generation antihistamines in allergic rhinitis]. ( Riechelmann, H, 2005) |
| "Triamcinolone is a commonly used synthetic corticosteroid that has recently been tested in a large clinical trial for chronic obstructive pulmonary disease and shown to have some benefits." | 2.41 | Triamcinolone: new and old indications. ( Doggrell, SA, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (41.67) | 18.2507 |
| 2000's | 12 (50.00) | 29.6817 |
| 2010's | 2 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Banla, M | 1 |
| Maneh, N | 1 |
| Vonor, K | 1 |
| Vonor, B | 1 |
| Nonon Saa, KB | 1 |
| Agba, A | 1 |
| Gantin, RG | 1 |
| Balo, KP | 1 |
| Soboslay, PT | 1 |
| Bakondé, B | 1 |
| Ozturk, AB | 1 |
| Celebioglu, E | 1 |
| Karakaya, G | 1 |
| Kalyoncu, AF | 1 |
| Torkildsen, GL | 2 |
| Gomes, P | 1 |
| Welch, D | 1 |
| Gopalan, G | 1 |
| Srinivasan, S | 1 |
| Jahnz-Rózyk, K | 1 |
| Targowski, T | 1 |
| Głodzinska-Wyszogrodzka, E | 1 |
| Płusa, T | 1 |
| Crampton, HJ | 1 |
| Riechelmann, H | 1 |
| Kirmaz, C | 1 |
| Aydemir, O | 1 |
| Bayrak, P | 1 |
| Yuksel, H | 1 |
| Ozenturk, O | 1 |
| Degirmenci, S | 1 |
| Bordignon, V | 1 |
| Burastero, SE | 1 |
| Rak, S | 1 |
| Yang, WH | 1 |
| Pedersen, MR | 1 |
| Durham, SR | 1 |
| Ousler, GW | 1 |
| Workman, DA | 1 |
| Buczyłko, K | 1 |
| Chwała, C | 1 |
| Zielińska-Bliźniewska, H | 1 |
| Wagner, A | 1 |
| Dzwonnik, A | 1 |
| Bahmer, FA | 1 |
| Ciprandi, G | 3 |
| Buscaglia, S | 2 |
| Marchesi, E | 3 |
| Danzig, M | 1 |
| Cuss, F | 1 |
| Canonica, GW | 3 |
| Bousquet, J | 1 |
| Chanal, I | 1 |
| Czarlewski, W | 1 |
| Michel, FB | 1 |
| Catrullo, A | 1 |
| Cerqueti, P | 1 |
| Tosca, M | 1 |
| Fiorino, N | 1 |
| Juniper, EF | 2 |
| Abelson, MB | 2 |
| Lanier, RQ | 1 |
| Welch, DL | 1 |
| Lanier, BQ | 1 |
| Gross, RD | 1 |
| Marks, BB | 1 |
| Cockrum, PC | 1 |
| Doggrell, SA | 1 |
| Boner, AL | 1 |
| Richelli, C | 1 |
| Castellani, C | 1 |
| Andreoli, A | 1 |
| Olsen, OT | 1 |
| Nüchel Petersen, L | 1 |
| Høi, L | 1 |
| Lorentzen, KA | 1 |
| Hindberg Rasmussen, W | 1 |
| Svendsen, UG | 1 |
| Pesce, GP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Double-blind, Placebo-controlled, Crossover, Single-center Study to Evaluate the Anti-allergic and Anti-inflammatory Effects of Multiple Doses of Desloratadine on Conjunctival Allergen Challenge-induced Ocular Signs and Symptoms[NCT00311844] | Phase 4 | 41 participants (Actual) | Interventional | 2005-03-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for loratadine and Conjunctivitis, Allergic
| Article | Year |
|---|---|
[Oral second generation antihistamines in allergic rhinitis].
Topics: Administration, Oral; Adult; Anti-Allergic Agents; Cetirizine; Child; Conjunctivitis, Allergic; Cont | 2005 |
Topical levocabastine--an effective alternative to oral antihistamines in seasonal allergic rhinoconjunctivitis.
Topics: Administration, Oral; Administration, Topical; Clinical Trials as Topic; Conjunctivitis, Allergic; D | 1995 |
Triamcinolone: new and old indications.
Topics: Administration, Intranasal; Adult; Aerosols; Androstadienes; Anti-Inflammatory Agents; Arthritis, Rh | 2001 |
17 trials available for loratadine and Conjunctivitis, Allergic
| Article | Year |
|---|---|
[Tropical endemic limbo-conjunctivitis (TELC) and allergic management: a preliminary study in Togolese children].
Topics: Adolescent; Anti-Allergic Agents; Child; Child, Preschool; Conjunctivitis, Allergic; Dexamethasone; | 2013 |
Protective efficacy of sunglasses on the conjunctival symptoms of seasonal rhinitis.
Topics: Adult; Anti-Inflammatory Agents; Budesonide; Conjunctivitis, Allergic; Eye Protective Devices; Femal | 2013 |
Evaluation of desloratadine on conjunctival allergen challenge-induced ocular symptoms.
Topics: Administration, Oral; Adult; Aged; Conjunctivitis, Allergic; Cross-Over Studies; Dose-Response Relat | 2009 |
Comparison of ketotifen fumarate ophthalmic solution alone, desloratadine alone, and their combination for inhibition of the signs and symptoms of seasonal allergic rhinoconjunctivitis in the conjunctival allergen challenge model: a double-masked, placebo
Topics: Adolescent; Adult; Aged; Allergens; Anti-Allergic Agents; Child; Conjunctivitis, Allergic; Double-Bl | 2003 |
Multiple daily administrations of low-dose sublingual immunotherapy in allergic rhinoconjunctivitis.
Topics: Administration, Sublingual; Adolescent; Adult; Allergens; Child; Child, Preschool; Conjunctivitis, A | 2006 |
Once-daily sublingual allergen-specific immunotherapy improves quality of life in patients with grass pollen-induced allergic rhinoconjunctivitis: a double-blind, randomised study.
Topics: Administration, Sublingual; Adolescent; Adult; Aged; Allergens; Anti-Allergic Agents; Conjunctivitis | 2007 |
An open-label, investigator-masked, crossover study of the ocular drying effects of two antihistamines, topical epinastine and systemic loratadine, in adult volunteers with seasonal allergic conjunctivitis.
Topics: Administration, Topical; Adolescent; Adult; Conjunctivitis, Allergic; Cross-Over Studies; Dibenzazep | 2007 |
Topical levocabastine compared with oral loratadine for the treatment of seasonal allergic rhinoconjunctivitis. Swedish GP Allergy Team.
Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Aerosols; Aged; Conjunctivitis, Al | 1994 |
Protective effect of loratadine on late phase reaction induced by conjunctival provocation test.
Topics: Allergens; Conjunctiva; Conjunctivitis, Allergic; Humans; Immunologic Tests; Loratadine; Time Factor | 1993 |
Evaluation of a composite scoring system in conjunctival challenge with allergen: reproducibility and evolution during loratadine treatment.
Topics: Adult; Anti-Allergic Agents; Conjunctivitis, Allergic; Cross-Over Studies; Double-Blind Method; Huma | 1995 |
Loratadine reduces the expression of ICAM-1.
Topics: Adolescent; Adult; Anti-Allergic Agents; Conjunctiva; Conjunctivitis, Allergic; Double-Blind Method; | 1998 |
The added benefit of local Patanol therapy when combined with systemic Claritin for the inhibition of ocular itching in the conjunctival antigen challenge model.
Topics: Administration, Oral; Adult; Allergens; Conjunctivitis, Allergic; Dibenzoxepins; Double-Blind Method | 1999 |
An evaluation of onset and duration of action of patanol (olopatadine hydrochloride ophthalmic solution 0.1%) compared to Claritin (loratadine 10 mg) tablets in acute allergic conjunctivitis in the conjunctival allergen challenge model.
Topics: Acute Disease; Allergens; Conjunctivitis, Allergic; Dibenzoxepins; Double-Blind Method; Drug Evaluat | 2000 |
Olopatadine ophthalmic solution adjunctive to loratadine compared with loratadine alone in patients with active seasonal allergic conjunctivitis symptoms.
Topics: Adolescent; Adult; Aged; Asthenia; Child; Conjunctivitis, Allergic; Dibenzoxepins; Drug Therapy, Com | 2001 |
Comparison of the effects of loratadine and astemizole in the treatment of children with seasonal allergic rhinoconjunctivitis.
Topics: Adolescent; Astemizole; Child; Conjunctivitis, Allergic; Cyproheptadine; Female; Histamine Antagonis | 1992 |
Comparison of loratadine and terfenadine in allergic seasonal rhinoconjunctivitis with emphasis on nasal stuffiness and peak flow.
Topics: Adolescent; Adult; Aged; Conjunctivitis, Allergic; Double-Blind Method; Female; Humans; Loratadine; | 1992 |
Protective effect of loratadine on specific conjunctival provocation test.
Topics: Adolescent; Adult; Aged; Conjunctiva; Conjunctivitis, Allergic; Cyproheptadine; Double-Blind Method; | 1991 |
4 other studies available for loratadine and Conjunctivitis, Allergic
| Article | Year |
|---|---|
Cc-chemokine eotaxin as a marker of efficacy of specific immunotherapy in patients with intermittent IgE-mediated allergic rhinoconjunctivitis.
Topics: Administration, Inhalation; Adult; Allergens; Anti-Allergic Agents; Betula; Biomarkers; Chemokines, | 2003 |
Sexual dysfunction in patients with allergic rhinoconjunctivitis.
Topics: Adult; Coitus; Conjunctivitis, Allergic; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Lib | 2005 |
[The influence of desloratadine on course of intermittens allergic rhinitis].
Topics: Adolescent; Adult; Child; Child, Preschool; Conjunctivitis, Allergic; Disease Progression; Female; H | 2005 |
Rhinitis management: the patient's perspective.
Topics: Adolescent; Adult; Child; Clinical Trials as Topic; Conjunctivitis, Allergic; Humans; Loratadine; Pa | 1998 |