loratadine has been researched along with Chemical and Drug Induced Liver Injury in 7 studies
Loratadine: A second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS) it lacks central nervous system depressing effects such as drowsiness.
loratadine : A benzocycloheptapyridine that is 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine substituted by a chloro group at position 8 and a 1-(ethoxycarbonyl)piperidin-4-ylidene group at position 11. It is a H1-receptor antagonist commonly employed in the treatment of allergic disorders.
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 2 |
| Morgan, RE | 1 |
| van Staden, CJ | 1 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Afshari, CA | 1 |
| Hamadeh, HK | 1 |
| Chen, M | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| Schöttker, B | 1 |
| Dösch, A | 1 |
| Kraemer, DM | 1 |
| Kim, H | 1 |
| Bindslev-Jensen, C | 1 |
| Najarian, JS | 1 |
| Schiano, TD | 1 |
| Bellary, SV | 1 |
| Cassidy, MJ | 1 |
| Thomas, RM | 1 |
| Black, M | 1 |
1 review available for loratadine and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
6 other studies available for loratadine and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
Severe hepatotoxicity after application of desloratadine and fluconazole.
Topics: Adult; Antifungal Agents; Chemical and Drug Induced Liver Injury; Contraindications; Drug Interactio | 2003 |
Reported case of severe hepatotoxicity likely due to fluconazole and not desloratadine.
Topics: Antifungal Agents; Chemical and Drug Induced Liver Injury; Fluconazole; Histamine H1 Antagonists, No | 2004 |
Hepatic necrosis.
Topics: Chemical and Drug Induced Liver Injury; Female; Humans; Liver Diseases; Loratadine; Middle Aged; Nec | 1996 |
Subfulminant liver failure and severe hepatotoxicity caused by loratadine use.
Topics: Adult; Chemical and Drug Induced Liver Injury; Female; Histamine H1 Antagonists; Humans; Liver; Lora | 1996 |