loratadine has been researched along with Bronchial Spasm in 5 studies
Loratadine: A second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS) it lacks central nervous system depressing effects such as drowsiness.
loratadine : A benzocycloheptapyridine that is 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine substituted by a chloro group at position 8 and a 1-(ethoxycarbonyl)piperidin-4-ylidene group at position 11. It is a H1-receptor antagonist commonly employed in the treatment of allergic disorders.
Bronchial Spasm: Spasmodic contraction of the smooth muscle of the bronchi.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present studies compared loratadine and terfenadine, another non-sedating antihistamine, for their ability to inhibit the bronchial response to histamine and other autacoids which have been implicated as contributing to the symptoms of an allergic reaction." | 3.67 | Antiallergic activity of loratadine, a non-sedating antihistamine. ( Chapman, RW; Gulbenkian, A; Kreutner, W; Siegel, MI, 1987) |
| "Desloratadine was shown to be a selective H1 antagonist with more potent antihistaminic activity in vitro than either loratadine or terfenadine (CAS 50679-08-8), as indicated by its displacement of 3H-mepyramine from H1 receptors in rat brain, guinea pig brain, and guinea pig lung, and by its antagonism of histamine-induced contractions of guinea pig ileum." | 1.31 | Preclinical pharmacology of desloratadine, a selective and nonsedating histamine H1 receptor antagonist. 1st communication: receptor selectivity, antihistaminic activity, and antiallergenic effects. ( Anthes, J; Barnett, A; Hey, JA; Kreutner, W; Tozzi, S; Young, S, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Llupià, J | 1 |
| Gras, J | 1 |
| Llenas, J | 1 |
| Kreutner, W | 4 |
| Hey, JA | 1 |
| Anthes, J | 1 |
| Barnett, A | 1 |
| Young, S | 1 |
| Tozzi, S | 1 |
| Billah, MM | 2 |
| Chapman, RW | 3 |
| Watnick, AS | 1 |
| Egan, RW | 2 |
| Siegel, MI | 3 |
| Gilchrest, H | 1 |
| Piwinski, JJ | 1 |
| Sherwood, J | 1 |
| West, RE | 1 |
| Gulbenkian, A | 1 |
5 other studies available for loratadine and Bronchial Spasm
| Article | Year |
|---|---|
Comparative antiallergic effects of second-generation H1-antihistamines ebastine, cetirizine and loratadine in preclinical models.
Topics: Aerosols; Airway Resistance; Algorithms; Animals; Anti-Allergic Agents; Bronchial Spasm; Butyropheno | 2003 |
Preclinical pharmacology of desloratadine, a selective and nonsedating histamine H1 receptor antagonist. 1st communication: receptor selectivity, antihistaminic activity, and antiallergenic effects.
Topics: Animals; Anti-Allergic Agents; Brain; Bronchial Spasm; Edema; Female; Guinea Pigs; Histamine H1 Anta | 2000 |
Sch 37370: a new drug combining antagonism of platelet-activating factor (PAF) with antagonism of histamine.
Topics: Animals; Antigens; Bronchial Spasm; Guinea Pigs; Histamine Antagonists; Humans; Hyperventilation; Lo | 1991 |
Sch 37370: a potent, orally active, dual antagonist of platelet-activating factor and histamine.
Topics: Administration, Oral; Animals; Binding, Competitive; Brain; Bronchial Spasm; Female; Guinea Pigs; Hi | 1990 |
Antiallergic activity of loratadine, a non-sedating antihistamine.
Topics: Animals; Benzhydryl Compounds; Bronchial Spasm; Calcium; Cyproheptadine; Guinea Pigs; Histamine Anta | 1987 |