loratadine has been researched along with Bronchial Hyperreactivity in 9 studies
Loratadine: A second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS) it lacks central nervous system depressing effects such as drowsiness.
loratadine : A benzocycloheptapyridine that is 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine substituted by a chloro group at position 8 and a 1-(ethoxycarbonyl)piperidin-4-ylidene group at position 11. It is a H1-receptor antagonist commonly employed in the treatment of allergic disorders.
Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The results of this study show that loratadine, employed as an adjuvant therapeutic agent for the treatment of allergic bronchial asthma has a positive effect on symptomatology." | 9.07 | [Allergic bronchial asthma treated with Loratadine]. ( Kroll, VM; Nothofer, B; Werdermann, K, 1993) |
| "We sought to evaluate the effect of DL on allergic-airway responses in mice after inhalation of the naturally occurring aeroallergen Aspergillus fumigatus (Af ) and to examine the effects of DL on specific immune responses to a defined protein antigen with the use of an ovalbumin (OVA) model of asthma." | 7.72 | Desloratadine inhibits allergen-induced airway inflammation and bronchial hyperresponsiveness and alters T-cell responses in murine models of asthma. ( Bryce, PJ; Geha, R; Oettgen, HC, 2003) |
| "The results of this study show that loratadine, employed as an adjuvant therapeutic agent for the treatment of allergic bronchial asthma has a positive effect on symptomatology." | 5.07 | [Allergic bronchial asthma treated with Loratadine]. ( Kroll, VM; Nothofer, B; Werdermann, K, 1993) |
| "We sought to evaluate the effect of DL on allergic-airway responses in mice after inhalation of the naturally occurring aeroallergen Aspergillus fumigatus (Af ) and to examine the effects of DL on specific immune responses to a defined protein antigen with the use of an ovalbumin (OVA) model of asthma." | 3.72 | Desloratadine inhibits allergen-induced airway inflammation and bronchial hyperresponsiveness and alters T-cell responses in murine models of asthma. ( Bryce, PJ; Geha, R; Oettgen, HC, 2003) |
| "Desloratadine is a potent antihistamine." | 2.73 | The effect of regular versus on-demand desloratadine treatment in children with allergic rhinitis. ( Adalioglu, G; Dizdar, EA; Dogan, C; Kalayci, O; Keskin, O; Sekerel, BE; Tuncer, A, 2007) |
| "Montelukast was not significantly different from placebo." | 2.71 | Effects of mediator antagonism on mannitol and adenosine monophosphate challenges. ( Anderson, SD; Brannan, JD; Currie, GP; Fowler, SJ; Haggart, K; Lee, DK; Lipworth, BJ; Wilson, AM, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 6 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Currie, GP | 1 |
| Haggart, K | 1 |
| Lee, DK | 1 |
| Fowler, SJ | 1 |
| Wilson, AM | 1 |
| Brannan, JD | 1 |
| Anderson, SD | 1 |
| Lipworth, BJ | 1 |
| Bryce, PJ | 1 |
| Geha, R | 1 |
| Oettgen, HC | 1 |
| Magnan, A | 1 |
| Blümchen, K | 1 |
| Gerhold, K | 1 |
| Thorade, I | 1 |
| Seib, C | 1 |
| Wahn, U | 1 |
| Hamelmann, E | 1 |
| Dizdar, EA | 1 |
| Sekerel, BE | 1 |
| Keskin, O | 1 |
| Kalayci, O | 1 |
| Adalioglu, G | 1 |
| Dogan, C | 1 |
| Tuncer, A | 1 |
| Kroll, VM | 1 |
| Nothofer, B | 1 |
| Werdermann, K | 1 |
| Kroczyńska-Bednarek, J | 1 |
| Gondorowicz, K | 1 |
| Kalinowska-Graczyk, M | 1 |
| Grzelewska-Rzymowska, I | 1 |
| Rozniecki, J | 1 |
1 review available for loratadine and Bronchial Hyperreactivity
| Article | Year |
|---|---|
[Airway hyperreactivity and respiratory allergy in children].
Topics: Allergens; Anti-Allergic Agents; Asthma; Bronchial Hyperreactivity; Chemotaxis, Leukocyte; Child; Ch | 1996 |
5 trials available for loratadine and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Effects of mediator antagonism on mannitol and adenosine monophosphate challenges.
Topics: Acetates; Adenosine Monophosphate; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation T | 2003 |
The effect of regular versus on-demand desloratadine treatment in children with allergic rhinitis.
Topics: Adolescent; Albuterol; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Bronchodilator Agents; | 2007 |
[Allergic bronchial asthma treated with Loratadine].
Topics: Adult; Asthma; Bronchial Hyperreactivity; Female; Humans; Loratadine; Lung Volume Measurements; Male | 1993 |
[Bronchial hyperresponsiveness in patients with seasonal allergic rhinitis and the influence of loratadine and beclomethasone on this hyperresponsiveness].
Topics: Adolescent; Adult; Anti-Allergic Agents; Beclomethasone; Bronchial Hyperreactivity; Female; Humans; | 1996 |
[Airway hyperreactivity and respiratory allergy in children].
Topics: Allergens; Anti-Allergic Agents; Asthma; Bronchial Hyperreactivity; Chemotaxis, Leukocyte; Child; Ch | 1996 |
4 other studies available for loratadine and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Desloratadine inhibits allergen-induced airway inflammation and bronchial hyperresponsiveness and alters T-cell responses in murine models of asthma.
Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Cytokines; Disease Models, Animal; Dose-Respo | 2003 |
[Respiratory allergies in the child and the adult].
Topics: Administration, Oral; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Allergens; Anti-Allergic Ag | 2004 |
Oral administration of desloratadine prior to sensitization prevents allergen-induced airway inflammation and hyper-reactivity in mice.
Topics: Administration, Oral; Allergens; Animals; Bronchial Hyperreactivity; Cells, Cultured; Female; Histam | 2004 |
[The third-generation antihistaminics. Can they prevent the tier change?].
Topics: Asthma; Bronchial Hyperreactivity; Histamine H1 Antagonists; Humans; Loratadine; Placebos; Randomize | 2002 |