loratadine has been researched along with Bilateral Headache in 7 studies
Loratadine: A second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS) it lacks central nervous system depressing effects such as drowsiness.
loratadine : A benzocycloheptapyridine that is 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine substituted by a chloro group at position 8 and a 1-(ethoxycarbonyl)piperidin-4-ylidene group at position 11. It is a H1-receptor antagonist commonly employed in the treatment of allergic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Desloratadine was superior to placebo in controlling pruritus and total symptoms after the first dose and maintained this superiority to the end of the study." | 9.09 | Once-daily desloratadine improves the signs and symptoms of chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled study. ( Bronsky, E; Gauger, A; Hein, R; Miller, B; Ring, J, 2001) |
| "Desloratadine was superior to placebo in controlling pruritus and total symptoms after the first dose and maintained this superiority to the end of the study." | 5.09 | Once-daily desloratadine improves the signs and symptoms of chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled study. ( Bronsky, E; Gauger, A; Hein, R; Miller, B; Ring, J, 2001) |
| "Cetirizine 10 mg was statistically significantly more efficacious than placebo in the treatment of SAR symptoms in children ages 6-11 years." | 2.84 | Randomized, placebo-controlled study of cetirizine and loratadine in children with seasonal allergic rhinitis. ( Berger, WE; Franklin, KB; LaForce, CF; Nayak, AS; Patel, MK; Urdaneta, ER; Wu, MM, 2017) |
| "Azelastine hydrochloride is an H1-receptor antagonist with antiinflammatory properties that is available in the US as Astelin Nasal Spray for the treatment of seasonal allergic rhinitis." | 2.69 | Double-blind trials of azelastine nasal spray monotherapy versus combination therapy with loratadine tablets and beclomethasone nasal spray in patients with seasonal allergic rhinitis. Rhinitis Study Groups. ( Berger, WE; Fineman, SM; Lieberman, P; Miles, RM, 1999) |
| "Desloratadine is a non-sedating, long-acting histamine H(1) receptor antagonist indicated for the symptomatic relief of allergic rhinitis (AR) and chronic idiopathic urticaria in patients aged>12 years." | 1.35 | Examining the tolerability of the non-sedating antihistamine desloratadine: a prescription-event monitoring study in England. ( Layton, D; Shakir, SA; Wilton, L, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nayak, AS | 1 |
| Berger, WE | 2 |
| LaForce, CF | 1 |
| Urdaneta, ER | 1 |
| Patel, MK | 1 |
| Franklin, KB | 1 |
| Wu, MM | 1 |
| Layton, D | 1 |
| Wilton, L | 1 |
| Shakir, SA | 1 |
| Scharf, M | 1 |
| Berkowitz, D | 1 |
| Jordana, G | 1 |
| Dolovich, J | 1 |
| Briscoe, MP | 1 |
| Day, JH | 1 |
| Drouin, MA | 1 |
| Gold, M | 1 |
| Robson, R | 1 |
| Stepner, N | 1 |
| Yang, W | 1 |
| Fineman, SM | 1 |
| Lieberman, P | 1 |
| Miles, RM | 1 |
| Ring, J | 1 |
| Hein, R | 1 |
| Gauger, A | 1 |
| Bronsky, E | 1 |
| Miller, B | 1 |
| Nyman, K | 1 |
| Bergman, U | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Proof of Concept Study to Evaluate Comparative Efficacy of an Azelastine/Fluticasone Combination Nasal Spray vs. Twice the Dose of Fluticasone in Persistent Allergic Rhinitis[NCT00845598] | Phase 4 | 0 participants (Actual) | Interventional | 2010-08-31 | Withdrawn (stopped due to Could not get IMP) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for loratadine and Bilateral Headache
| Article | Year |
|---|---|
Randomized, placebo-controlled study of cetirizine and loratadine in children with seasonal allergic rhinitis.
Topics: Anti-Allergic Agents; Cetirizine; Child; Female; Headache; Humans; Loratadine; Male; Pharyngitis; Rh | 2017 |
Effects of desloratadine and alcohol coadministration on psychomotor performance.
Topics: Adult; Arousal; Ataxia; Double-Blind Method; Drug Interactions; Ethanol; Fatigue; Female; Headache; | 2007 |
Intranasal fluticasone propionate versus loratadine in the treatment of adolescent patients with seasonal allergic rhinitis.
Topics: Administration, Intranasal; Adolescent; Androstadienes; Anti-Allergic Agents; Child; Double-Blind Me | 1996 |
Double-blind trials of azelastine nasal spray monotherapy versus combination therapy with loratadine tablets and beclomethasone nasal spray in patients with seasonal allergic rhinitis. Rhinitis Study Groups.
Topics: Administration, Intranasal; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Beclomethasone; Child | 1999 |
Once-daily desloratadine improves the signs and symptoms of chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled study.
Topics: Adolescent; Adult; Aged; Cholinergic Antagonists; Chronic Disease; Dizziness; Double-Blind Method; D | 2001 |
2 other studies available for loratadine and Bilateral Headache
| Article | Year |
|---|---|
Examining the tolerability of the non-sedating antihistamine desloratadine: a prescription-event monitoring study in England.
Topics: Adult; Cohort Studies; Drug Prescriptions; Drug Utilization; England; Female; Headache; Histamine H1 | 2009 |
[Severe adverse effect of the anti-allergy drug loratadine--warning against prolonged use of non-prescription drugs].
Topics: Adolescent; Adolescent Behavior; Cyproheptadine; Dose-Response Relationship, Drug; Headache; Histami | 1992 |