loratadine has been researched along with Anasarca in 9 studies
Loratadine: A second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS) it lacks central nervous system depressing effects such as drowsiness.
loratadine : A benzocycloheptapyridine that is 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine substituted by a chloro group at position 8 and a 1-(ethoxycarbonyl)piperidin-4-ylidene group at position 11. It is a H1-receptor antagonist commonly employed in the treatment of allergic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study we examined the effect of drugs interfering with TNF expression (thalidomide) and activity (infliximab) and compared it to that of a H(1)R histamine receptor antagonist (loratadine) in a model of histamine-induced rat hind-paw oedema formation." | 7.75 | Evidence for the contribution of tumour necrosis factor in oedema formation induced by histamine in the hind paw of the rat. ( Goulas, A; Kalokasidis, K; Kokkas, B; Mirtsou, V; Molyva, D, 2009) |
| " In this study we examined the effect of drugs interfering with TNF expression (thalidomide) and activity (infliximab) and compared it to that of a H(1)R histamine receptor antagonist (loratadine) in a model of histamine-induced rat hind-paw oedema formation." | 3.75 | Evidence for the contribution of tumour necrosis factor in oedema formation induced by histamine in the hind paw of the rat. ( Goulas, A; Kalokasidis, K; Kokkas, B; Mirtsou, V; Molyva, D, 2009) |
| "Envenomation and death resulting from snakebites represent a significant public health problem worldwide, particularly in tropical and subtropical regions." | 1.62 | Case Report: Recent Case Reports of Levant Blunt-Nosed Viper Macrovipera lebetina obtusa Snakebites in Iran. ( Abd El-Aziz, TM; Al-Sabi, A; Kazemi, SM; Long, C; Shoulkamy, MI, 2021) |
| "The Cetirizine study groups were given once daily doses of 1 mg/ml cetirizine for 30 (S30 Group) or 60 (S60 Group) days." | 1.40 | Effects of oral intake of cetirizine HCl and desloratadine molecules on the middle ear mucosa: an experimental animal study. ( Arslanoglu, S; Inan, S; Kirtay, S; Onal, K; Ozkul, Y; Ozkut, M; Songu, M, 2014) |
| "The edema was produced in a dose- and time-dependent manner." | 1.39 | Pharmaco-modulations of induced edema and vascular permeability changes by Vipera lebetina venom: inflammatory mechanisms. ( Laraba-Djebari, F; Sebia-Amrane, F, 2013) |
| "Loratadine pretreatment, but neither guanethidine nor indomethacin, reduced edema." | 1.32 | Nociceptive and edematogenic responses elicited by a crude bristle extract of Lonomia obliqua caterpillars. ( de Castro Bastos, L; Guimarães, JA; Tonussi, CR; Veiga, AB, 2004) |
| "Desloratadine was shown to be a selective H1 antagonist with more potent antihistaminic activity in vitro than either loratadine or terfenadine (CAS 50679-08-8), as indicated by its displacement of 3H-mepyramine from H1 receptors in rat brain, guinea pig brain, and guinea pig lung, and by its antagonism of histamine-induced contractions of guinea pig ileum." | 1.31 | Preclinical pharmacology of desloratadine, a selective and nonsedating histamine H1 receptor antagonist. 1st communication: receptor selectivity, antihistaminic activity, and antiallergenic effects. ( Anthes, J; Barnett, A; Hey, JA; Kreutner, W; Tozzi, S; Young, S, 2000) |
| "Loratadine inhibited an increase in dye leakage into the nasal cavity in rats." | 1.29 | Effect of loratadine on immediate and delayed type hypersensitivity reactions. ( Akagi, M; Izushi, K; Kamei, C; Mio, M; Nakamura, S; Tasaka, K; Yoshida, T, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Kazemi, SM | 1 |
| Al-Sabi, A | 1 |
| Long, C | 1 |
| Shoulkamy, MI | 1 |
| Abd El-Aziz, TM | 1 |
| Songu, M | 1 |
| Ozkul, Y | 1 |
| Kirtay, S | 1 |
| Arslanoglu, S | 1 |
| Ozkut, M | 1 |
| Inan, S | 1 |
| Onal, K | 1 |
| Jie, Q | 1 |
| Kodithuwakku, ND | 1 |
| Yuan, X | 1 |
| He, G | 1 |
| Chen, M | 1 |
| Xu, S | 1 |
| Wu, Y | 1 |
| Wang, XR | 1 |
| Zhou, C | 1 |
| Zhong, ZD | 1 |
| Duan, Q | 1 |
| Du, AY | 1 |
| Jing, G | 1 |
| Kalokasidis, K | 1 |
| Molyva, D | 1 |
| Mirtsou, V | 1 |
| Kokkas, B | 1 |
| Goulas, A | 1 |
| Sebia-Amrane, F | 1 |
| Laraba-Djebari, F | 1 |
| de Castro Bastos, L | 1 |
| Veiga, AB | 1 |
| Guimarães, JA | 1 |
| Tonussi, CR | 1 |
| Tasaka, K | 1 |
| Kamei, C | 1 |
| Akagi, M | 1 |
| Mio, M | 1 |
| Izushi, K | 1 |
| Yoshida, T | 1 |
| Nakamura, S | 1 |
| Kreutner, W | 1 |
| Hey, JA | 1 |
| Anthes, J | 1 |
| Barnett, A | 1 |
| Young, S | 1 |
| Tozzi, S | 1 |
9 other studies available for loratadine and Anasarca
| Article | Year |
|---|---|
Case Report: Recent Case Reports of Levant Blunt-Nosed Viper Macrovipera lebetina obtusa Snakebites in Iran.
Topics: Adolescent; Adult; Animals; Antivenins; Child; Edema; Female; Histamine Antagonists; Humans; Hypoten | 2021 |
Effects of oral intake of cetirizine HCl and desloratadine molecules on the middle ear mucosa: an experimental animal study.
Topics: Administration, Oral; Animals; Cetirizine; Ear, Middle; Edema; Histamine H1 Antagonists, Non-Sedatin | 2014 |
Anti-allergic and anti-inflammatory properties of a potent histamine H1 receptor antagonist, desloratadine citrate disodium injection, and its anti-inflammatory mechanism on EA.hy926 endothelial cells.
Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Capillary Permeability; Cell Survival; Chlo | 2015 |
[Effect of Modified Danggui Yinzi on Delayed Allergy in Model Mice with Qi-Blood Deficiency Syndrome].
Topics: Animals; Disease Models, Animal; Drugs, Chinese Herbal; Edema; Hypersensitivity, Delayed; Immunoglob | 2016 |
Evidence for the contribution of tumour necrosis factor in oedema formation induced by histamine in the hind paw of the rat.
Topics: Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; Dose-Response Relationship, Drug; Edema; | 2009 |
Pharmaco-modulations of induced edema and vascular permeability changes by Vipera lebetina venom: inflammatory mechanisms.
Topics: Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Capil | 2013 |
Nociceptive and edematogenic responses elicited by a crude bristle extract of Lonomia obliqua caterpillars.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthropod Venoms; Dose-Response Relationship, Drug | 2004 |
Effect of loratadine on immediate and delayed type hypersensitivity reactions.
Topics: Acetylcholine; Animals; Edema; Granuloma; Guinea Pigs; Histamine; Histamine Release; Hypersensitivit | 1995 |
Preclinical pharmacology of desloratadine, a selective and nonsedating histamine H1 receptor antagonist. 1st communication: receptor selectivity, antihistaminic activity, and antiallergenic effects.
Topics: Animals; Anti-Allergic Agents; Brain; Bronchial Spasm; Edema; Female; Guinea Pigs; Histamine H1 Anta | 2000 |