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loratadine and Airway Hyper-Responsiveness

loratadine has been researched along with Airway Hyper-Responsiveness in 7 studies

Loratadine: A second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS) it lacks central nervous system depressing effects such as drowsiness.
loratadine : A benzocycloheptapyridine that is 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine substituted by a chloro group at position 8 and a 1-(ethoxycarbonyl)piperidin-4-ylidene group at position 11. It is a H1-receptor antagonist commonly employed in the treatment of allergic disorders.

Research Excerpts

ExcerptRelevanceReference
"The results of this study show that loratadine, employed as an adjuvant therapeutic agent for the treatment of allergic bronchial asthma has a positive effect on symptomatology."9.07[Allergic bronchial asthma treated with Loratadine]. ( Kroll, VM; Nothofer, B; Werdermann, K, 1993)
"Sixteen atopic patients with mild-to-moderate asthma of whom 10 were receiving inhaled corticosteroid therapy (all had positive results to house dust mite on skin prick testing) were randomized in a double-blind, placebo-controlled, cross-over fashion to receive single doses of 5 mg of desloratadine, 180 mg of fexofenadine hydrochloride (FEX), 5 mg of levocetirizine dihydrochloride (LEV), or placebo, with AMP challenge performed 12 hours after dosing."5.10Comparative in vivo bioactivity of modern H1-antihistamines on AMP challenge in atopic asthma. ( Bates, CE; Currie, GP; Lee, DK; Lipworth, BJ, 2003)
"The results of this study show that loratadine, employed as an adjuvant therapeutic agent for the treatment of allergic bronchial asthma has a positive effect on symptomatology."5.07[Allergic bronchial asthma treated with Loratadine]. ( Kroll, VM; Nothofer, B; Werdermann, K, 1993)
"Desloratadine was used as a probe to further elucidate the mechanisms involved during an allergic response."2.42Anti-inflammatory properties of desloratadine. ( Agrawal, DK, 2004)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (57.14)18.2507
2000's3 (42.86)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lee, DK1
Bates, CE1
Currie, GP1
Lipworth, BJ1
Magnan, A1
Agrawal, DK1
Sherwood, JE1
Hutt, DA1
Kreutner, W1
Morton, JB1
Chapman, RW1
Kroll, VM1
Nothofer, B1
Werdermann, K1
Horak, F1
Toth, J1
Hirschwehr, R1
Marks, B1
Stübner, UP1
Jäger, S1
Berger, U1
Schleinzer, K1
Günczler, P1

Reviews

2 reviews available for loratadine and Airway Hyper-Responsiveness

ArticleYear
Anti-inflammatory properties of desloratadine.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2004, Volume: 34, Issue:9

    Topics: Cell Adhesion; Cytokines; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Models, Immuno

2004
[Airway hyperreactivity and respiratory allergy in children].
    Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993), 1996, Volume: 43 Spec No

    Topics: Allergens; Anti-Allergic Agents; Asthma; Bronchial Hyperreactivity; Chemotaxis, Leukocyte; Child; Ch

1996

Trials

4 trials available for loratadine and Airway Hyper-Responsiveness

ArticleYear
Comparative in vivo bioactivity of modern H1-antihistamines on AMP challenge in atopic asthma.
    The Journal of allergy and clinical immunology, 2003, Volume: 111, Issue:2

    Topics: Acetates; Adenosine Monophosphate; Adult; Aged; Asthma; Bronchial Provocation Tests; Cetirizine; Cro

2003
[Allergic bronchial asthma treated with Loratadine].
    Fortschritte der Medizin, 1993, Feb-20, Volume: 111, Issue:5

    Topics: Adult; Asthma; Bronchial Hyperreactivity; Female; Humans; Loratadine; Lung Volume Measurements; Male

1993
[Airway hyperreactivity and respiratory allergy in children].
    Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993), 1996, Volume: 43 Spec No

    Topics: Allergens; Anti-Allergic Agents; Asthma; Bronchial Hyperreactivity; Chemotaxis, Leukocyte; Child; Ch

1996
Effect of continuous allergen challenge on clinical symptoms and mediator release in dust-mite-allergic patients.
    Allergy, 1998, Volume: 53, Issue:1

    Topics: Adult; Antigens, Dermatophagoides; Blood Proteins; Bronchial Provocation Tests; Chymases; Cross-Over

1998

Other Studies

2 other studies available for loratadine and Airway Hyper-Responsiveness

ArticleYear
[Respiratory allergies in the child and the adult].
    La Revue du praticien, 2004, Jan-31, Volume: 54, Issue:2

    Topics: Administration, Oral; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Allergens; Anti-Allergic Ag

2004
A magnetic resonance imaging evaluation of histamine-mediated allergic response in the guinea pig nasopharynx.
    The Journal of allergy and clinical immunology, 1993, Volume: 92, Issue:3

    Topics: Animals; Guinea Pigs; Histamine; Loratadine; Magnetic Resonance Imaging; Male; Methacholine Chloride

1993