loratadine has been researched along with Abnormalities, Drug-Induced in 5 studies
Loratadine: A second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS) it lacks central nervous system depressing effects such as drowsiness.
loratadine : A benzocycloheptapyridine that is 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine substituted by a chloro group at position 8 and a 1-(ethoxycarbonyl)piperidin-4-ylidene group at position 11. It is a H1-receptor antagonist commonly employed in the treatment of allergic disorders.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We sought to determine whether the use of loratadine in the first trimester of pregnancy was associated with an increased risk for major malformations." | 9.10 | Fetal safety of loratadine use in the first trimester of pregnancy: a multicenter study. ( Addis, A; Bar-Oz, B; Berkovitch, M; Caprara, D; Coutinho, CJ; Jovanovski, E; Koren, G; Moretti, ME; Schüler-Faccini, L, 2003) |
| "Callers who were counseled by the Israeli Teratogen Information Service in regard to loratadine or OAH exposure during pregnancy were prospectively collected and followed up." | 9.10 | Pregnancy outcome after gestational exposure to loratadine or antihistamines: a prospective controlled cohort study. ( Aharonovich, A; Arnon, J; Diav-Citrin, O; Moerman, L; Ornoy, A; Shechtman, S; Wajnberg, R, 2003) |
| "This meta-analysis was designed to assess the strength of the association between loratadine and hypospadias." | 8.84 | Risk of hypospadias in offspring of women using loratadine during pregnancy: a systematic review and meta-analysis. ( Koren, G; Moretti, ME; Nayak, S; Schwarz, EB, 2008) |
| "Hypospadias is a birth defect that affects approximately seven in 1,000 male infants in the United States." | 5.32 | Evaluation of an association between loratadine and hypospadias--United States, 1997-2001. ( , 2004) |
| "We sought to determine whether the use of loratadine in the first trimester of pregnancy was associated with an increased risk for major malformations." | 5.10 | Fetal safety of loratadine use in the first trimester of pregnancy: a multicenter study. ( Addis, A; Bar-Oz, B; Berkovitch, M; Caprara, D; Coutinho, CJ; Jovanovski, E; Koren, G; Moretti, ME; Schüler-Faccini, L, 2003) |
| "Callers who were counseled by the Israeli Teratogen Information Service in regard to loratadine or OAH exposure during pregnancy were prospectively collected and followed up." | 5.10 | Pregnancy outcome after gestational exposure to loratadine or antihistamines: a prospective controlled cohort study. ( Aharonovich, A; Arnon, J; Diav-Citrin, O; Moerman, L; Ornoy, A; Shechtman, S; Wajnberg, R, 2003) |
| "This meta-analysis was designed to assess the strength of the association between loratadine and hypospadias." | 4.84 | Risk of hypospadias in offspring of women using loratadine during pregnancy: a systematic review and meta-analysis. ( Koren, G; Moretti, ME; Nayak, S; Schwarz, EB, 2008) |
| "Hypospadias is a birth defect that affects approximately seven in 1,000 male infants in the United States." | 1.32 | Evaluation of an association between loratadine and hypospadias--United States, 1997-2001. ( , 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schwarz, EB | 1 |
| Moretti, ME | 2 |
| Nayak, S | 1 |
| Koren, G | 2 |
| Caprara, D | 1 |
| Coutinho, CJ | 1 |
| Bar-Oz, B | 1 |
| Berkovitch, M | 1 |
| Addis, A | 1 |
| Jovanovski, E | 1 |
| Schüler-Faccini, L | 1 |
| Diav-Citrin, O | 1 |
| Shechtman, S | 1 |
| Aharonovich, A | 1 |
| Moerman, L | 1 |
| Arnon, J | 1 |
| Wajnberg, R | 1 |
| Ornoy, A | 1 |
| Pedersen, L | 1 |
| Nørgaard, M | 1 |
| Rothman, KJ | 1 |
| Sørensen, HT | 1 |
1 review available for loratadine and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Risk of hypospadias in offspring of women using loratadine during pregnancy: a systematic review and meta-analysis.
Topics: Abnormalities, Drug-Induced; Anti-Allergic Agents; Female; Humans; Hypospadias; Loratadine; Male; Mo | 2008 |
2 trials available for loratadine and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Fetal safety of loratadine use in the first trimester of pregnancy: a multicenter study.
Topics: Abnormalities, Drug-Induced; Adult; Anti-Allergic Agents; Control Groups; Dose-Response Relationship | 2003 |
Pregnancy outcome after gestational exposure to loratadine or antihistamines: a prospective controlled cohort study.
Topics: Abnormalities, Drug-Induced; Adult; Cohort Studies; Female; Follow-Up Studies; Histamine Antagonists | 2003 |
2 other studies available for loratadine and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Evaluation of an association between loratadine and hypospadias--United States, 1997-2001.
Topics: Abnormalities, Drug-Induced; Anti-Allergic Agents; Humans; Hypospadias; Infant, Newborn; Loratadine; | 2004 |
Loratadine during pregnancy and hypospadias.
Topics: Abnormalities, Drug-Induced; Anti-Allergic Agents; Case-Control Studies; Denmark; Female; Humans; Hy | 2008 |