Page last updated: 2024-08-26

lopinavir and Malaria

lopinavir has been researched along with Malaria in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (10.00)29.6817
2010's14 (70.00)24.3611
2020's4 (20.00)2.80

Authors

AuthorsStudies
Chen, L; Chen, X; He, Z; Peng, N; Qin, L; You, J1
Lopes, F; Moreira, R; Mota, MM; Prudêncio, M; Rodrigues, T1
Chen, X; Qin, L; Xu, W; Zhao, S1
Aweeka, F; Ehrlich, H; Freeman, T; French, J; Goodwin, J; Huang, L; Kajubi, R; Kay, K; Li, F; Mwebaza, N; Ou, J; Parikh, S; Riggs, M; Ruiz-Garcia, A; Wade, M; Wang, K1
Karbwang, J; Na-Bangchang, K; Rajoli, RKR; Saeheng, T; Siccardi, M1
Aweeka, FT; Barnes, KI; Byakika-Kibwika, P; Bygbjerg, IC; Chijioke-Nwauche, I; Denti, P; Francis, J; Hoglund, RM; Khoo, SH; Kredo, T; Lamorde, M; Lemnge, MM; Merry, C; Nyagonde, N; Parikh, S; Scarsi, KK; Sutherland, CJ; Tarning, J; Vestergaard, LS; Walimbwa, SI; Workman, L1
Abideen, G; Adeniji, H; Adeuja, O; Agbaje, EO; Akanmu, AS; Akinleye, MO; Akinyede, AA; Busari, AW; Hassan, OO; Ken-Owotor, C; Kogbe, S; Ogunfowokan, T; Onwujuobi, AG; Oreagba, IA; Owolabi, ET; Usman, SO1
Ahmed, BS; Ferris, RE; Phelps, BR; Reuben, EB1
Achan, J; Charlebois, E; Dorsey, G; Havlir, D; Ikilezi, G; Kakuru, A; Kamya, M; Mwangwa, F; Rosenthal, PJ; Ruel, TD1
Abiodun, OO; Akinbo, J; Ojurongbe, O1
Achan, J; Arinaitwe, E; Charlebois, E; Clark, TD; Dorsey, G; Havlir, D; Ikilezi, G; Kakuru, A; Kamya, MR; Muhindo, MK; Mwangwa, F; Rosenthal, PJ; Ruel, T; Tappero, JW1
Achan, J; Ades, V; Charlebois, ED; Clark, TD; Cohan, D; Dorsey, G; Havlir, DV; Kamya, MR; Luwedde, F; Mwesigwa, J; Natureeba, P; Nzarubara, B; Okong, P; Plenty, A1
Achan, J; Ades, V; Charlebois, ED; Clark, TD; Cohan, D; Gandhi, M; Havlir, DV; Kamya, MR; Koss, CA; Luwedde, F; Mwesigwa, J; Natureeba, P; Nzarubara, B; Plenty, A; Ruel, T1
Borkowsky, W; Chen, J; Dixit, S; Duffy, PE; Hobbs, CV; Lambert, L; Neal, J; Orr-Gonzalez, S; Penzak, SR; Sahu, T; Wu, Y; Zeleski, K1
Abiodun, OO; Gbimadee, N; Gbotosho, GO1
Borkowsky, W; Coppi, A; Hobbs, CV; Kirmse, B; Marsh, K; Sinnis, P; Voza, T1
Aba, YT; Aoussi, EF; Bissagnene, E; Eholié, SP; Ehui, E; Kadio, A; Kakou, AR; Kassi, A; Ondounda, M; Ouattara, I; Tanon, A1
Chipato, T; Cole, SR; Currier, JS; D'Amico, R; Eron, JJ; Hosseinipour, M; Hughes, MD; Lockman, S; McCarthy, JS; Meshnick, SR; Poole, C; Porter, KA; Salata, R; Sawe, FK; Shaffer, D; Siika, A; Skinner-Adams, TS; Stringer, E; Zheng, Y1
Butterworth, AS; Chipato, T; Currier, JS; D'Amico, R; Eron, JJ; Hosseinipour, MC; Lockman, S; McCarthy, JS; Meshnick, SR; Porter, KA; Salata, R; Sawe, F; Shaffer, D; Siika, A; Skinner-Adams, TS; Stringer, E1
Achan, J; Aweeka, F; Charlebois, E; Clark, TD; Dorsey, G; Havlir, D; Ikilezi, G; Kakuru, A; Kamya, MR; Nsanzabana, C; Rosenthal, PJ; Ruel, T1

Reviews

2 review(s) available for lopinavir and Malaria

ArticleYear
Targeting the liver stage of malaria parasites: a yet unmet goal.
    Journal of medicinal chemistry, 2012, Feb-09, Volume: 55, Issue:3

    Topics: Animals; Antimalarials; Humans; Life Cycle Stages; Liver; Malaria; Plasmodium; Structure-Activity Relationship

2012
An Individual Participant Data Population Pharmacokinetic Meta-analysis of Drug-Drug Interactions between Lumefantrine and Commonly Used Antiretroviral Treatment.
    Antimicrobial agents and chemotherapy, 2020, 04-21, Volume: 64, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Antimalarials; Antiretroviral Therapy, Highly Active; Artemether, Lumefantrine Drug Combination; Body Weight; Computer Simulation; Drug Interactions; Female; HIV Infections; Humans; Lopinavir; Lumefantrine; Malaria; Male; Middle Aged; Monte Carlo Method; Ritonavir; Young Adult

2020

Trials

7 trial(s) available for lopinavir and Malaria

ArticleYear
Virologic and immunologic outcomes of HIV-infected Ugandan children randomized to lopinavir/ritonavir or nonnucleoside reverse transcriptase inhibitor therapy.
    Journal of acquired immune deficiency syndromes (1999), 2014, Apr-15, Volume: 65, Issue:5

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; Humans; Infant; Lopinavir; Malaria; Male; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Treatment Outcome; Uganda; Viral Load

2014
Artemisinin-based combination therapies are efficacious and safe for treatment of uncomplicated malaria in HIV-infected Ugandan children.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2014, Aug-01, Volume: 59, Issue:3

    Topics: Antimalarials; Artemisinins; Child, Preschool; Cohort Studies; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Lopinavir; Malaria; Male; Nevirapine; Parasitemia; Quinolines; Reverse Transcriptase Inhibitors; Ritonavir; Treatment Outcome; Uganda

2014
Lopinavir/ritonavir-based antiretroviral treatment (ART) versus efavirenz-based ART for the prevention of malaria among HIV-infected pregnant women.
    The Journal of infectious diseases, 2014, Dec-15, Volume: 210, Issue:12

    Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Antimalarials; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Female; HIV Infections; Humans; Infant, Newborn; Lopinavir; Malaria; Pregnancy; Pregnancy Complications, Infectious; Ritonavir; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Young Adult

2014
Efficacy and safety of lopinavir/ritonavir versus efavirenz-based antiretroviral therapy in HIV-infected pregnant Ugandan women.
    AIDS (London, England), 2015, Jan-14, Volume: 29, Issue:2

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Breast Feeding; CD4 Lymphocyte Count; Cyclopropanes; Female; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lopinavir; Malaria; Pregnancy; Pregnancy Complications, Infectious; Ritonavir; Uganda; Viral Load

2015
HIV-1 protease inhibitors and clinical malaria: a secondary analysis of the AIDS Clinical Trials Group A5208 study.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:2

    Topics: Adenine; Adult; Anti-HIV Agents; Deoxycytidine; Emtricitabine; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Incidence; Lopinavir; Malaria; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; Ritonavir; Tenofovir; Treatment Outcome

2012
The frequency of malaria is similar among women receiving either lopinavir/ritonavir or nevirapine-based antiretroviral treatment.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Female; HIV Infections; HIV Protease Inhibitors; Humans; Lopinavir; Malaria; Nevirapine; Ritonavir

2012
Antiretroviral agents and prevention of malaria in HIV-infected Ugandan children.
    The New England journal of medicine, 2012, Nov-29, Volume: 367, Issue:22

    Topics: Anti-Retroviral Agents; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; HIV Infections; HIV Protease Inhibitors; Humans; Incidence; Infant; Kaplan-Meier Estimate; Lopinavir; Malaria; Male; Reverse Transcriptase Inhibitors; Ritonavir; Secondary Prevention; Uganda

2012

Other Studies

11 other study(ies) available for lopinavir and Malaria

ArticleYear
Synergy of human immunodeficiency virus protease inhibitors with chloroquine against Plasmodium falciparum in vitro and Plasmodium chabaudi in vivo.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7

    Topics: Animals; Antimalarials; Atazanavir Sulfate; Chloroquine; Drug Resistance; Drug Synergism; Female; HIV Protease Inhibitors; Humans; In Vitro Techniques; Lopinavir; Malaria; Mice; Nelfinavir; Oligopeptides; Plasmodium chabaudi; Plasmodium falciparum; Pyridines; Pyrimidinones; Ritonavir; Saquinavir

2008
Ritonavir-boosted indinavir but not lopinavir inhibits erythrocytic stage Plasmodium knowlesi malaria in rhesus macaques.
    Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7

    Topics: Animals; Antimalarials; Dose-Response Relationship, Drug; Erythrocytes; Indinavir; Macaca mulatta; Malaria; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium knowlesi; Ritonavir; Structure-Activity Relationship

2015
Impact of Drug Exposure on Resistance Selection Following Artemether-Lumefantrine Treatment for Malaria in Children With and Without HIV in Uganda.
    Clinical pharmacology and therapeutics, 2023, Volume: 113, Issue:3

    Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Drug Combinations; Fluorenes; HIV Infections; Humans; Lopinavir; Lumefantrine; Malaria; Malaria, Falciparum; Nevirapine; Ritonavir; Uganda

2023
Physiologically-Based Pharmacokinetic Modeling for Optimal Dosage Prediction of Quinine Coadministered With Ritonavir-Boosted Lopinavir.
    Clinical pharmacology and therapeutics, 2020, Volume: 107, Issue:5

    Topics: Adolescent; Adult; Antimalarials; Coinfection; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; HIV Infections; HIV Protease Inhibitors; Humans; Lopinavir; Malaria; Middle Aged; Models, Biological; Quinine; Ritonavir; Young Adult

2020
Effect of nevirapine, efavirenz and lopinavir/ritonavir on the therapeutic concentration and toxicity of lumefantrine in people living with HIV at Lagos University Teaching Hospital, Nigeria.
    Journal of pharmacological sciences, 2020, Volume: 144, Issue:3

    Topics: Adult; Alkynes; Anti-Retroviral Agents; Antimalarials; Artemether, Lumefantrine Drug Combination; Benzoxazines; Cyclopropanes; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; Humans; Lopinavir; Malaria; Male; Middle Aged; Nevirapine; Nigeria; Ritonavir; Treatment Outcome; Young Adult

2020
Does a significant reduction in malaria risk make lopinavir/ritonavir-based ART cost-effective for children with HIV in co-endemic, low-resource settings?
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2014, Volume: 108, Issue:1

    Topics: Anti-Retroviral Agents; Child, Preschool; Cohort Studies; Coinfection; Cost-Benefit Analysis; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Incidence; Infant; Lopinavir; Malaria; Male; Quality-Adjusted Life Years; Ritonavir; Uganda

2014
The effect of lopinavir/ritonavir on the antimalarial activity of artemether or artemether/lumefantrine in a mouse model of Plasmodium berghei.
    Journal of chemotherapy (Florence, Italy), 2015, Volume: 27, Issue:1

    Topics: Animals; Anti-Retroviral Agents; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Coinfection; Disease Models, Animal; Drug Combinations; Drug Interactions; Ethanolamines; Fluorenes; HIV Infections; Lopinavir; Malaria; Mice; Plasmodium berghei; Ritonavir

2015
Neither the HIV protease inhibitor lopinavir-ritonavir nor the antimicrobial trimethoprim-sulfamethoxazole prevent malaria relapse in plasmodium cynomolgi-infected non-human primates.
    PloS one, 2014, Volume: 9, Issue:12

    Topics: Animals; Antimalarials; Female; HIV Protease Inhibitors; Lopinavir; Macaca mulatta; Malaria; Male; Plasmodium cynomolgi; Ritonavir; Sulfamethoxazole; Trimethoprim

2014
Lopinavir/ritonavir enhanced the antimalarial activity of amodiaquine and artesunate in a mouse model of Plasmodium berghei.
    Journal of chemotherapy (Florence, Italy), 2016, Volume: 28, Issue:6

    Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; HIV Protease Inhibitors; Lopinavir; Malaria; Mice; Plasmodium berghei; Ritonavir

2016
HIV protease inhibitors inhibit the development of preerythrocytic-stage plasmodium parasites.
    The Journal of infectious diseases, 2009, Jan-01, Volume: 199, Issue:1

    Topics: Animals; Anopheles; Female; HIV Infections; HIV Protease Inhibitors; Lopinavir; Malaria; Mice; Plasmodium; Plasmodium berghei; Plasmodium yoelii; Pyrimidinones; Ritonavir

2009
[Two cases of Fanconi's syndrome induced by tenofovir in the Ivory Coast].
    Medecine et maladies infectieuses, 2011, Volume: 41, Issue:2

    Topics: Adenine; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cote d'Ivoire; Cyclopropanes; Drug Therapy, Combination; Enterobacter aerogenes; Enterobacteriaceae Infections; Fanconi Syndrome; Female; HIV Infections; HIV-1; Humans; Lamivudine; Lopinavir; Malaria; Male; Middle Aged; Organophosphonates; Pyelonephritis; Pyrimidinones; Ritonavir; Tenofovir

2011