loperamide has been researched along with Tachycardia, Ventricular in 7 studies
Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.
Tachycardia, Ventricular: An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Loperamide, a μ-opioid receptor agonist, can cause cardiotoxicity by inhibiting the potassium ion channel and slowing cardiomyocyte repolarization." | 4.02 | Loperamide Toxicity Revealing Apical Hypertrophic Cardiomyopathy. ( Chitturi, KR; Clewing, M; Hatcher, C; Khan, N; Nagueh, SF, 2021) |
| "Loperamide is an antidiarrheal medication deemed by the U." | 3.81 | Ventricular tachycardia associated with high-dose chronic loperamide use. ( Lonardo, NW; Mulamalla, R; Spinner, HL; Stehlik, J, 2015) |
| "Loperamide is an over-the-counter anti-diarrheal medication that is inexpensive, easily accessible, and widely used." | 1.48 | Loperamide abuse cardiotoxicity. Should loperamide still be an over the counter medication? ( Idris, A; Kaye, K; Mihora, DC, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Wolfes, J | 1 |
| Ellermann, C | 1 |
| Burde, S | 1 |
| Leitz, P | 1 |
| Bögeholz, N | 1 |
| Willy, K | 1 |
| Fehr, M | 1 |
| Reinke, F | 1 |
| Eckardt, L | 1 |
| Frommeyer, G | 1 |
| Lowe, CE | 1 |
| Winniford, MD | 1 |
| Tanawuttiwat, T | 1 |
| Khan, N | 1 |
| Chitturi, KR | 1 |
| Hatcher, C | 1 |
| Clewing, M | 1 |
| Nagueh, SF | 1 |
| Idris, A | 1 |
| Mihora, DC | 1 |
| Kaye, K | 1 |
| Ahmed, A | 1 |
| Freeland, S | 1 |
| Steinberg, L | 1 |
| Prystowsky, EN | 1 |
| Spinner, HL | 1 |
| Lonardo, NW | 1 |
| Mulamalla, R | 1 |
| Stehlik, J | 1 |
| Lasoff, DR | 1 |
| Schneir, A | 1 |
7 other studies available for loperamide and Tachycardia, Ventricular
| Article | Year |
|---|---|
Divergent Electrophysiological Effects of Loperamide and Naloxone in a Sensitive Whole-Heart Model.
Topics: Action Potentials; Analgesics, Opioid; Animals; Antidiarrheals; Cardiac Pacing, Artificial; Cardioto | 2021 |
Syncope in a Young Woman.
Topics: Adult; Electrocardiography; Female; Humans; Loperamide; Prescription Drug Misuse; Syncope; Tachycard | 2020 |
Loperamide Toxicity Revealing Apical Hypertrophic Cardiomyopathy.
Topics: Adult; Antidiarrheals; Cardiomyopathy, Hypertrophic; Cardiotoxicity; DNA Mutational Analysis; Electr | 2021 |
Loperamide abuse cardiotoxicity. Should loperamide still be an over the counter medication?
Topics: Adult; Antidiarrheals; Echocardiography; Electrocardiography; Female; Humans; Loperamide; Nonprescri | 2018 |
Wide complex tachycardia and cardiomyopathy: What would you do?
Topics: Antidiarrheals; Cardiomyopathies; Female; Humans; Loperamide; Tachycardia, Ventricular; Young Adult | 2018 |
Ventricular tachycardia associated with high-dose chronic loperamide use.
Topics: Antidiarrheals; Cholecystectomy; Diarrhea; Dose-Response Relationship, Drug; Drug Overdose; Female; | 2015 |
Ventricular Dysrhythmias from Loperamide Misuse.
Topics: Arrhythmias, Cardiac; Cimetidine; Heart Conduction System; Humans; Loperamide; Male; Narcotic Antago | 2016 |