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loperamide and Psychotic Disorders

loperamide has been researched along with Psychotic Disorders in 2 studies

Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.

Psychotic Disorders: Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)

Research Excerpts

ExcerptRelevanceReference
"Psychosis is caused by interactions with other drugs or by pharmacogenetic vulnerabilities that cause heightened responses to chloroquine or mefloquine alone, mediated through dopamine, acetylcholine, serotonin, P-glycoprotein, inhibited cortical activity, deranged calcium homeostasis, and impaired synaptogenesis."1.33Drug interactions and pharmacogenetic reactions are the basis for chloroquine and mefloquine-induced psychosis. ( Alisky, JM; Chertkova, EL; Iczkowski, KA, 2006)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Eronen, M1
Putkonen, H1
Hallikainen, T1
Vartiainen, H1
Alisky, JM1
Chertkova, EL1
Iczkowski, KA1

Other Studies

2 other studies available for loperamide and Psychotic Disorders

ArticleYear
Lethal gastroenteritis associated with clozapine and loperamide.
    The American journal of psychiatry, 2003, Volume: 160, Issue:12

    Topics: Adult; Antidiarrheals; Antipsychotic Agents; Bacillaceae Infections; Bacillus cereus; Clozapine; Dru

2003
Drug interactions and pharmacogenetic reactions are the basis for chloroquine and mefloquine-induced psychosis.
    Medical hypotheses, 2006, Volume: 67, Issue:5

    Topics: Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chloroquine; Drug Interactio

2006