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loperamide and Pregnancy

loperamide has been researched along with Pregnancy in 13 studies

Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"Loperamide is a synthetic piperidine derivative used for the treatment of both acute and chronic diarrhea."9.09Prospective, controlled, multicentre study of loperamide in pregnancy. ( Addis, A; Arnon, J; Einarson, A; Koren, G; Malm, H; Mastroiacovo, P; Ornoy, A, 2000)
"The objectives of this prospective non-concurrent cohort study were to confirm the efficacy of vaginal misoprostol for early pregnancy termination and to determine whether the incidence of side effects is lower with prophylactic loperamide and acetaminophen."9.09Early pregnancy termination with vaginal misoprostol combined with loperamide and acetaminophen prophylaxis. ( Harwood, B; Jain, JK; Meckstroth, KR; Mishell, DR, 2001)
"To study delivery outcome including presence of infant congenital malformations after maternal use of loperamide in early pregnancy."7.74Maternal use of loperamide in early pregnancy and delivery outcome. ( Källén, B; Nilsson, E; Otterblad Olausson, P, 2008)
"Loperamide is a synthetic piperidine derivative used for the treatment of both acute and chronic diarrhea."5.09Prospective, controlled, multicentre study of loperamide in pregnancy. ( Addis, A; Arnon, J; Einarson, A; Koren, G; Malm, H; Mastroiacovo, P; Ornoy, A, 2000)
"The objectives of this prospective non-concurrent cohort study were to confirm the efficacy of vaginal misoprostol for early pregnancy termination and to determine whether the incidence of side effects is lower with prophylactic loperamide and acetaminophen."5.09Early pregnancy termination with vaginal misoprostol combined with loperamide and acetaminophen prophylaxis. ( Harwood, B; Jain, JK; Meckstroth, KR; Mishell, DR, 2001)
"To study delivery outcome including presence of infant congenital malformations after maternal use of loperamide in early pregnancy."3.74Maternal use of loperamide in early pregnancy and delivery outcome. ( Källén, B; Nilsson, E; Otterblad Olausson, P, 2008)
"Loperamide, a new antidiarrhoeal compound, effectively antagonised prostaglandin induced diarrhoea in adult healthy male volunteers and in patients undergoing pregnancy termination with prostaglandins."3.65The effect of loperamide on prostaglandin induced diarrhoea in rat and man. ( Adaikan, PG; Karim, SM, 1977)
"Prednisolone was most effective with a response rate of 82%, but the required dose was often high and the effect was not sustained after withdrawal."1.29Collagenous colitis: a retrospective study of clinical presentation and treatment in 163 patients. ( Abrahamsson, H; Bohr, J; Eriksson, S; Järnerot, G; Tysk, C, 1996)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19905 (38.46)18.7374
1990's2 (15.38)18.2507
2000's5 (38.46)29.6817
2010's0 (0.00)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Wang, A1
Nguyen, M1
Diaz, J1
Smith, T1
Diemert, DJ1
Källén, B1
Nilsson, E1
Otterblad Olausson, P1
Martin, S1
Bohr, J1
Tysk, C1
Eriksson, S1
Abrahamsson, H1
Järnerot, G1
Einarson, A1
Mastroiacovo, P1
Arnon, J1
Ornoy, A1
Addis, A1
Malm, H1
Koren, G1
Jain, JK1
Harwood, B1
Meckstroth, KR1
Mishell, DR1
Karim, SM2
Adaikan, PG1
Ratnam, SS1
Daugherty, LM1
Osler, M1
Lange, AP1
Moth, I1
Thomsen Pedersen, G1
Westergaard, JG1

Reviews

2 reviews available for loperamide and Pregnancy

ArticleYear
Prevention and self-treatment of traveler's diarrhea.
    Clinical microbiology reviews, 2006, Volume: 19, Issue:3

    Topics: Anti-Infective Agents; Antibiotic Prophylaxis; Antidiarrheals; Developing Countries; Diarrhea; Femal

2006
Loperamide hydrochloride.
    American pharmacy, 1990, Volume: NS30, Issue:12

    Topics: Animals; Diarrhea; Drug Administration Schedule; Drug Interactions; Female; Humans; Loperamide; Nonp

1990

Trials

3 trials available for loperamide and Pregnancy

ArticleYear
Prospective, controlled, multicentre study of loperamide in pregnancy.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2000, Volume: 14, Issue:3

    Topics: Abnormalities, Drug-Induced; Antidiarrheals; Diarrhea; Female; Follow-Up Studies; Humans; Loperamide

2000
Early pregnancy termination with vaginal misoprostol combined with loperamide and acetaminophen prophylaxis.
    Contraception, 2001, Volume: 63, Issue:4

    Topics: Abortifacient Agents, Nonsteroidal; Abortion, Induced; Acetaminophen; Administration, Intravaginal;

2001
Loperamide for diarrhea.
    The Medical letter on drugs and therapeutics, 1977, Sep-09, Volume: 19, Issue:18

    Topics: Adult; Biopharmaceutics; Child, Preschool; Clinical Trials as Topic; Diarrhea; Diphenoxylate; Double

1977

Other Studies

8 other studies available for loperamide and Pregnancy

ArticleYear
Loperamide toxicity mimicking peripartum cardiomyopathy.
    The American journal of emergency medicine, 2020, Volume: 38, Issue:3

    Topics: Adult; Antidiarrheals; Cardiomyopathies; Diagnosis, Differential; Drug Overdose; Electrocardiography

2020
Maternal use of loperamide in early pregnancy and delivery outcome.
    Acta paediatrica (Oslo, Norway : 1992), 2008, Volume: 97, Issue:5

    Topics: Abnormalities, Drug-Induced; Adult; Antidiarrheals; Apgar Score; Delivery, Obstetric; Female; Humans

2008
Pharmaceutical review. Modium capsules.
    The Lamp, 1980, Volume: 37, Issue:1

    Topics: Animals; Female; Humans; Loperamide; Piperidines; Pregnancy

1980
Collagenous colitis: a retrospective study of clinical presentation and treatment in 163 patients.
    Gut, 1996, Volume: 39, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Anticholesteremic Agents; Anti

1996
Advice for travelers.
    The Medical letter on drugs and therapeutics, 2002, Apr-15, Volume: 44, Issue:1128

    Topics: Africa; Altitude Sickness; Asia; Chloroquine; Ciprofloxacin; Contraindications; Diarrhea; Female; He

2002
The effect of loperamide on prostaglandin induced diarrhoea in rat and man.
    Prostaglandins, 1977, Volume: 13, Issue:2

    Topics: Abortion, Induced; Animals; Cricetinae; Diarrhea; Drug Evaluation, Preclinical; Female; Humans; Lope

1977
Termination of abnormal intrauterine pregnancies with intramuscular administration of dihomo 15 methyl prostaglandin F 2alpha.
    British journal of obstetrics and gynaecology, 1976, Volume: 83, Issue:11

    Topics: Abortion, Missed; Abortion, Therapeutic; Anencephaly; Diarrhea; Female; Fetal Death; Humans; Hydatid

1976
15(S)-15-methyl-prostaglandin F2 alpha used for induction of delivery in the case of intra-uterine fetal death.
    Acta obstetricia et gynecologica Scandinavica, 1985, Volume: 64, Issue:2

    Topics: Abortion, Induced; Adult; Carboprost; Diphenoxylate; Female; Fetal Death; Gastrointestinal Diseases;

1985