Page last updated: 2024-10-30

loperamide and Obesity

loperamide has been researched along with Obesity in 6 studies

Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
"The effect of loperamide and diphenoxylate on diarrhoea following jejuno-ileostomy for morbid obesity was investigated in 27 patients by means of a randomized fixed sample size, three-period cross-over trial."9.05Diarrhoea following jejuno-ileostomy for morbid obesity. A randomised trial of loperamide and diphenoxylate. ( Andersen, B; Gudmand-Høyer, E; Skovbjerg, H; Wille-Jørgensen, P, 1982)
"We present the case of a 14-year-old boy with obesity, hypertension, and chronic loperamide abuse who presented to our facility with symptoms of opioid withdrawal and type 1 Brugada pattern on an electrocardiogram."7.88Brugada Syndrome Associated With Adolescent Loperamide Abuse. ( Cohen, M; Stefek, B; Wolfe, LT, 2018)
" bolus of naloxone at a dose of 125 microgram per kilogram of body weight; 48 hours later, each patient received 16 mg of loperamide p."5.09Hypothalamic-pituitary-adrenal axis sensitivity to opioids in women with polycystic ovary syndrome. ( Barini, A; Ciampelli, M; Cinque, B; Cucinelli, F; Guido, M; Lanzone, A, 2000)
"The effect of loperamide and diphenoxylate on diarrhoea following jejuno-ileostomy for morbid obesity was investigated in 27 patients by means of a randomized fixed sample size, three-period cross-over trial."5.05Diarrhoea following jejuno-ileostomy for morbid obesity. A randomised trial of loperamide and diphenoxylate. ( Andersen, B; Gudmand-Høyer, E; Skovbjerg, H; Wille-Jørgensen, P, 1982)
"We present the case of a 14-year-old boy with obesity, hypertension, and chronic loperamide abuse who presented to our facility with symptoms of opioid withdrawal and type 1 Brugada pattern on an electrocardiogram."3.88Brugada Syndrome Associated With Adolescent Loperamide Abuse. ( Cohen, M; Stefek, B; Wolfe, LT, 2018)
"Loperamide has beneficial effects on stool consistency and continence in obese subjects taking orlistat."2.71The effects of loperamide on continence problems and anorectal function in obese subjects taking orlistat. ( Fox, M; Fried, M; Menne, D; Schwizer, W; Stutz, B; Thumshirn, M, 2005)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's2 (33.33)18.2507
2000's2 (33.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stefek, B1
Wolfe, LT1
Cohen, M1
Fox, M1
Stutz, B1
Menne, D1
Fried, M1
Schwizer, W1
Thumshirn, M1
Wille-Jørgensen, P1
Gudmand-Høyer, E1
Skovbjerg, H1
Andersen, B1
Bernini, GP1
Argenio, GF1
Cerri, F1
Franchi, F1
Buzi, F1
Corna, A1
Pilotta, A1
Negrini, F1
Lombardi, A1
Re, T1
Ambrosi, B1
Ciampelli, M1
Guido, M1
Cucinelli, F1
Cinque, B1
Barini, A1
Lanzone, A1

Trials

4 trials available for loperamide and Obesity

ArticleYear
The effects of loperamide on continence problems and anorectal function in obese subjects taking orlistat.
    Digestive diseases and sciences, 2005, Volume: 50, Issue:9

    Topics: Adult; Anal Canal; Anti-Obesity Agents; Antidiarrheals; Double-Blind Method; Fecal Incontinence; Fem

2005
Diarrhoea following jejuno-ileostomy for morbid obesity. A randomised trial of loperamide and diphenoxylate.
    Acta chirurgica Scandinavica, 1982, Volume: 148, Issue:2

    Topics: Adult; Clinical Trials as Topic; Diarrhea; Diphenoxylate; Female; Humans; Ileum; Isonipecotic Acids;

1982
Loperamide test: a simple and highly specific screening test for hypercortisolism in children and adolescents.
    Acta paediatrica (Oslo, Norway : 1992), 1997, Volume: 86, Issue:11

    Topics: Adolescent; Adrenocortical Hyperfunction; Adult; Child; Dexamethasone; Female; Glucocorticoids; Huma

1997
Hypothalamic-pituitary-adrenal axis sensitivity to opioids in women with polycystic ovary syndrome.
    Fertility and sterility, 2000, Volume: 73, Issue:4

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Body Weight; Female; Humans; Hydrocortisone; Hyp

2000

Other Studies

2 other studies available for loperamide and Obesity

ArticleYear
Brugada Syndrome Associated With Adolescent Loperamide Abuse.
    Pediatrics, 2018, Volume: 142, Issue:4

    Topics: Adolescent; Analgesics, Opioid; Antidiarrheals; Brugada Syndrome; Humans; Loperamide; Male; Mutation

2018
Comparison between the suppressive effects of dexamethasone and loperamide on cortisol and ACTH secretion in some pathological conditions.
    Journal of endocrinological investigation, 1994, Volume: 17, Issue:10

    Topics: Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Age

1994