loperamide has been researched along with Nerve Pain in 4 studies
Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Loperamide treatment significantly attenuated mechanical, and cold hypersensitivity and produced significant place preference behaviour in neuropathic rats indicating its potential to treat both evoked and spontaneous pain." | 1.91 | Loperamide, a peripheral Mu-Opioid receptor agonist, attenuates chemotherapy-induced neuropathic pain in rats. ( Chouhan, D; Gadepalli, A; Tiwari, V; Ummadisetty, O, 2023) |
| "The present results suggest that thermal hyperalgesia in experimental neuropathic pain can be reduced through activation of peripheral delta-opioid receptors." | 1.34 | Antihyperalgesic effects of loperamide in a model of rat neuropathic pain are mediated by peripheral delta-opioid receptors. ( Hruby, VJ; Porreca, F; Shinoda, K, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gadepalli, A | 1 |
| Ummadisetty, O | 1 |
| Chouhan, D | 1 |
| Tiwari, V | 1 |
| Ringkamp, M | 2 |
| Tal, M | 1 |
| Hartke, TV | 2 |
| Wooten, M | 1 |
| McKelvy, A | 1 |
| Turnquist, BP | 1 |
| Guan, Y | 2 |
| Meyer, RA | 2 |
| Raja, SN | 2 |
| Shinoda, K | 1 |
| Hruby, VJ | 1 |
| Porreca, F | 1 |
| Johanek, LM | 1 |
| Shim, B | 1 |
| Tao, YX | 1 |
4 other studies available for loperamide and Nerve Pain
| Article | Year |
|---|---|
Loperamide, a peripheral Mu-Opioid receptor agonist, attenuates chemotherapy-induced neuropathic pain in rats.
Topics: Analgesics, Opioid; Animals; Antineoplastic Agents; Loperamide; Neuralgia; Rats; Receptors, Opioid | 2023 |
Local loperamide injection reduces mechanosensitivity of rat cutaneous, nociceptive C-fibers.
Topics: Analgesics, Opioid; Animals; Electrophysiological Phenomena; Hyperalgesia; Injections; Loperamide; M | 2012 |
Antihyperalgesic effects of loperamide in a model of rat neuropathic pain are mediated by peripheral delta-opioid receptors.
Topics: Analgesics; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Dru | 2007 |
Peripherally acting mu-opioid receptor agonist attenuates neuropathic pain in rats after L5 spinal nerve injury.
Topics: Analgesics, Opioid; Animals; Loperamide; Lumbar Vertebrae; Male; Neuralgia; Peripheral Nervous Syste | 2008 |