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loperamide and Muscle Relaxation

loperamide has been researched along with Muscle Relaxation in 7 studies

Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research Excerpts

ExcerptRelevanceReference
" serraefolia significantly delayed the onset of tonic seizures induced by strychnine and pentylenetetrazol; besides, it diminished the death rate and number of animals that exhibited convulsions."3.69Evaluation of the calcium-antagonist, antidiarrhoeic and central nervous system activities of Baccharis serraefolia. ( Aguilar-Santamaría, L; Tortoriello, J, 1996)
" Dose-response study on the prostate strip was performed by cumulative administration of loperamide 0."1.37Loperamide-induced rat prostate relaxation through activation of peripheral µ-opioid receptors. ( Chen, IH; Cheng, JT; Tong, YC; Yu, BC, 2011)
"2 mM) shifted the Ca++ dose-response curves to the right, similar to that produced by verapamil (0."1.33Synthesis and smooth muscle-selective relaxant activity of a piperidine analogue: 1-(4'-fluorophenacyl)-4-hydroxy-4-phenyl-piperidinium chloride. ( Aftab, MT; Ghayur, MN; Gilani, AH; Saify, ZS; Taqvi, SI, 2006)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's1 (14.29)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hsu, SL1
Chung, HH3
Chen, IH2
Tong, YC2
Cheng, JT3
Yu, BC1
Lee, LM1
Lin, CS1
Lin, KC1
Chen, W1
Taqvi, SI1
Ghayur, MN1
Gilani, AH1
Saify, ZS1
Aftab, MT1
Farouk, R1
Duthie, GS1
Pryde, A1
Bartolo, DC1
Tortoriello, J1
Aguilar-Santamaría, L1

Other Studies

7 other studies available for loperamide and Muscle Relaxation

ArticleYear
Alteration of loperamide-induced prostate relaxation in high-fat diet-fed rats.
    TheScientificWorldJournal, 2014, Volume: 2014

    Topics: Animals; Blood Pressure; Body Weight; Diet, High-Fat; Feeding Behavior; In Vitro Techniques; Loperam

2014
Loperamide-induced rat prostate relaxation through activation of peripheral µ-opioid receptors.
    Neurourology and urodynamics, 2011, Volume: 30, Issue:3

    Topics: Analysis of Variance; Animals; Blotting, Western; Dose-Response Relationship, Drug; Glyburide; In Vi

2011
Urinary bladder relaxation through activation of opioid μ-receptors induced by loperamide is increased in diabetic rats.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2012, Volume: 120, Issue:6

    Topics: Animals; Antidiarrheals; Cells, Cultured; Diabetes Mellitus, Experimental; Glyburide; Hypoglycemic A

2012
Opiate-induced constipation related to activation of small intestine opioid μ2-receptors.
    World journal of gastroenterology, 2012, Mar-28, Volume: 18, Issue:12

    Topics: Acetylcholine; Analgesics, Opioid; Animals; Antidiarrheals; Constipation; Cyclic AMP; Cyclic AMP-Dep

2012
Synthesis and smooth muscle-selective relaxant activity of a piperidine analogue: 1-(4'-fluorophenacyl)-4-hydroxy-4-phenyl-piperidinium chloride.
    Archives of pharmacal research, 2006, Volume: 29, Issue:1

    Topics: Acetylcholine; Animals; Antidiarrheals; Aorta, Thoracic; Calcium; Dose-Response Relationship, Drug;

2006
Abnormal transient internal sphincter relaxation in idiopathic pruritus ani: physiological evidence from ambulatory monitoring.
    The British journal of surgery, 1994, Volume: 81, Issue:4

    Topics: Adult; Aged; Anal Canal; Electromyography; Humans; Loperamide; Male; Middle Aged; Monitoring, Physio

1994
Evaluation of the calcium-antagonist, antidiarrhoeic and central nervous system activities of Baccharis serraefolia.
    Journal of ethnopharmacology, 1996, Volume: 53, Issue:3

    Topics: Administration, Oral; Analysis of Variance; Animals; Antidiarrheals; Calcium; Convulsants; Dose-Resp

1996