loperamide has been researched along with Leukemia in 2 studies
Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study compares maximal daily doses of loperamide to escalating doses of continuous intravenous (CI) octreotide acetate in bone marrow transplant (BMT) and leukemia patients." | 9.08 | Randomized trial of loperamide versus dose escalation of octreotide acetate for chemotherapy-induced diarrhea in bone marrow transplant and leukemia patients. ( Davidson, TG; Dix, SP; Geller, RB; Gilmore, CE; Holland, HK; Lin, LS; Topping, DL; Wingard, JR, 1995) |
| "This study compares maximal daily doses of loperamide to escalating doses of continuous intravenous (CI) octreotide acetate in bone marrow transplant (BMT) and leukemia patients." | 5.08 | Randomized trial of loperamide versus dose escalation of octreotide acetate for chemotherapy-induced diarrhea in bone marrow transplant and leukemia patients. ( Davidson, TG; Dix, SP; Geller, RB; Gilmore, CE; Holland, HK; Lin, LS; Topping, DL; Wingard, JR, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, ZH | 1 |
| Li, DD | 1 |
| Chen, WL | 1 |
| You, QD | 1 |
| Guo, XK | 1 |
| Geller, RB | 1 |
| Gilmore, CE | 1 |
| Dix, SP | 1 |
| Lin, LS | 1 |
| Topping, DL | 1 |
| Davidson, TG | 1 |
| Holland, HK | 1 |
| Wingard, JR | 1 |
1 review available for loperamide and Leukemia
| Article | Year |
|---|---|
Targeting protein-protein interaction between MLL1 and reciprocal proteins for leukemia therapy.
Topics: Animals; Dose-Response Relationship, Drug; Histone-Lysine N-Methyltransferase; Humans; Leukemia; Mol | 2018 |
1 trial available for loperamide and Leukemia
| Article | Year |
|---|---|
Randomized trial of loperamide versus dose escalation of octreotide acetate for chemotherapy-induced diarrhea in bone marrow transplant and leukemia patients.
Topics: Adult; Aged; Antidiarrheals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplanta | 1995 |