loperamide has been researched along with Injuries, Radiation in 7 studies
Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of loperamide-N-oxide, a new peripheral opiate agonist precursor, on gastrointestinal function were evaluated in 18 patients with diarrhoea caused by chronic radiation enteritis." | 9.07 | Gastrointestinal function in chronic radiation enteritis--effects of loperamide-N-oxide. ( Chatterton, BE; Horowitz, M; Muecke, T; Robb, T; Russo, A; Yeoh, EK, 1993) |
| "45 patients with diarrheas appearing after exposure of the gastro-intestinal region to ionizing radiation were given loperamide in the course of a study." | 7.66 | [Studies using loperamide in patients with diarrhea following telecobalt irradiation of malignant abdominal tumors (author's transl)]. ( Behdjati, F; Geginat, G; Green, E; Kaeferstein, D, 1978) |
| " Efficacy endpoints were incidence and severity of radiation-induced diarrhea, daily number of bowel movements, and the time from the start of the study to the use of loperamide as rescue medication." | 5.12 | Use of probiotics for prevention of radiation-induced diarrhea. ( De Renzis, C; Delia, P; Donato, V; Famularo, G; Frosina, P; Messina, G; Sansotta, G, 2007) |
| "The effects of loperamide-N-oxide, a new peripheral opiate agonist precursor, on gastrointestinal function were evaluated in 18 patients with diarrhoea caused by chronic radiation enteritis." | 5.07 | Gastrointestinal function in chronic radiation enteritis--effects of loperamide-N-oxide. ( Chatterton, BE; Horowitz, M; Muecke, T; Robb, T; Russo, A; Yeoh, EK, 1993) |
| ")-induced emesis in ferrets and substantially decreased loperamide (0." | 3.68 | Resinferatoxin, an ultrapotent capsaicin analogue, has anti-emetic properties in the ferret. ( Andrews, PL; Bhandari, P, 1993) |
| "45 patients with diarrheas appearing after exposure of the gastro-intestinal region to ionizing radiation were given loperamide in the course of a study." | 3.66 | [Studies using loperamide in patients with diarrhea following telecobalt irradiation of malignant abdominal tumors (author's transl)]. ( Behdjati, F; Geginat, G; Green, E; Kaeferstein, D, 1978) |
| "Radiation enteritis is a severe problem in patients receiving irradiation of the abdomen or pelvis in the course of cancer treatment." | 2.44 | Medical prevention and treatment of acute and chronic radiation induced enteritis--is there any proven therapy? a short review. ( Böcker, U; Singer, MV; Wenz, F; Zimmerer, T, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Linn, YH | 1 |
| Thu, KK | 1 |
| Win, NHH | 1 |
| Delia, P | 1 |
| Sansotta, G | 1 |
| Donato, V | 1 |
| Frosina, P | 1 |
| Messina, G | 1 |
| De Renzis, C | 1 |
| Famularo, G | 1 |
| Zimmerer, T | 1 |
| Böcker, U | 1 |
| Wenz, F | 1 |
| Singer, MV | 1 |
| Andrews, PL | 1 |
| Bhandari, P | 1 |
| Yeoh, EK | 1 |
| Horowitz, M | 1 |
| Russo, A | 1 |
| Muecke, T | 1 |
| Robb, T | 1 |
| Chatterton, BE | 1 |
| Geginat, G | 1 |
| Behdjati, F | 1 |
| Green, E | 1 |
| Kaeferstein, D | 1 |
| Henriksson, R | 1 |
| Franzén, L | 1 |
| Littbrand, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Distinct Shifts in the Microbiota Are Associated With Iodine-131 Therapy and Hypothyroidism[NCT03574051] | Early Phase 1 | 30 participants (Anticipated) | Interventional | 2018-05-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for loperamide and Injuries, Radiation
| Article | Year |
|---|---|
Medical prevention and treatment of acute and chronic radiation induced enteritis--is there any proven therapy? a short review.
Topics: Abdominal Neoplasms; Acute Disease; Chronic Disease; Combined Modality Therapy; Controlled Clinical | 2008 |
4 trials available for loperamide and Injuries, Radiation
| Article | Year |
|---|---|
Effect of Probiotics for the Prevention of Acute Radiation-Induced Diarrhoea Among Cervical Cancer Patients: a Randomized Double-Blind Placebo-Controlled Study.
Topics: Acute Disease; Adult; Diarrhea; Double-Blind Method; Female; Humans; Loperamide; Middle Aged; Probio | 2019 |
Use of probiotics for prevention of radiation-induced diarrhea.
Topics: Antidiarrheals; Colonic Neoplasms; Diarrhea; Dose-Response Relationship, Drug; Double-Blind Method; | 2007 |
Gastrointestinal function in chronic radiation enteritis--effects of loperamide-N-oxide.
Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Diarrhea; Digestive System; Double-Blind Method; En | 1993 |
Effects of sucralfate on acute and late bowel discomfort following radiotherapy of pelvic cancer.
Topics: Diarrhea; Double-Blind Method; Humans; Intestines; Loperamide; Male; Pelvis; Prostatic Neoplasms; Ra | 1992 |
2 other studies available for loperamide and Injuries, Radiation
| Article | Year |
|---|---|
Resinferatoxin, an ultrapotent capsaicin analogue, has anti-emetic properties in the ferret.
Topics: Animals; Antiemetics; Behavior, Animal; Blood Pressure; Body Temperature; Capsaicin; Copper; Copper | 1993 |
[Studies using loperamide in patients with diarrhea following telecobalt irradiation of malignant abdominal tumors (author's transl)].
Topics: Abdominal Neoplasms; Adult; Aged; Diarrhea; Female; Humans; Loperamide; Middle Aged; Piperidines; Ra | 1978 |