loperamide has been researched along with Hypothermia, Accidental in 2 studies
Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Loperamide significantly induced antinociception, hypothermia, and hypolocomotion (but not catalepsy) at high doses and dose-dependently reduced gastrointestinal motor function, with the intestine exhibiting higher sensitivity than the stomach." | 7.91 | Radiographic dose-dependency study of loperamide effects on gastrointestinal motor function in the rat. Temporal relationship with nausea-like behavior. ( Abalo, R; Girón, R; Martín-Fontelles, MI; Vera, G, 2019) |
| "Loperamide significantly induced antinociception, hypothermia, and hypolocomotion (but not catalepsy) at high doses and dose-dependently reduced gastrointestinal motor function, with the intestine exhibiting higher sensitivity than the stomach." | 3.91 | Radiographic dose-dependency study of loperamide effects on gastrointestinal motor function in the rat. Temporal relationship with nausea-like behavior. ( Abalo, R; Girón, R; Martín-Fontelles, MI; Vera, G, 2019) |
| "We have examined the effects of the psychostimulant d-amphetamine and the neuroleptic haloperidol on hypothermia induced by intraperitoneal injection of the centrally penetrating opioids morphine, fentanyl and sufentanil and the peripherally acting opioid loperamide." | 3.72 | Morphine and d-amphetamine nullify each others' hypothermic effects in mice. ( Baker, A; Meert, T, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vera, G | 1 |
| Girón, R | 1 |
| Martín-Fontelles, MI | 1 |
| Abalo, R | 1 |
| Baker, A | 1 |
| Meert, T | 1 |
2 other studies available for loperamide and Hypothermia, Accidental
| Article | Year |
|---|---|
Radiographic dose-dependency study of loperamide effects on gastrointestinal motor function in the rat. Temporal relationship with nausea-like behavior.
Topics: Animals; Antidiarrheals; Dose-Response Relationship, Drug; Gastrointestinal Motility; Hypothermia; L | 2019 |
Morphine and d-amphetamine nullify each others' hypothermic effects in mice.
Topics: Analgesics, Opioid; Animals; Dextroamphetamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Do | 2003 |