loperamide has been researched along with Heart Diseases in 2 studies
Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.
Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.
| Excerpt | Relevance | Reference |
|---|---|---|
| "High-dose loperamide is often used for the acute management of chemotherapy-induced diarrhea, with a maximum daily dosing of up to 24 mg." | 8.98 | Loperamide and cardiac events: Is high-dose use still safe for chemotherapy-induced diarrhea? ( de Lemos, ML; Guenter, J; Kletas, V, 2018) |
| "The anti-diarrheal drug loperamide is a mu-opioid agonist with poor systemic bioavailability at standard doses." | 5.56 | [Torsade de pointes following repeated massive loperamide ingestions]. ( Carlsson, H; Höjer, J; Myllymäki, L; Westerbergh, J, 2020) |
| "High-dose loperamide is often used for the acute management of chemotherapy-induced diarrhea, with a maximum daily dosing of up to 24 mg." | 4.98 | Loperamide and cardiac events: Is high-dose use still safe for chemotherapy-induced diarrhea? ( de Lemos, ML; Guenter, J; Kletas, V, 2018) |
| "The anti-diarrheal drug loperamide is a mu-opioid agonist with poor systemic bioavailability at standard doses." | 1.56 | [Torsade de pointes following repeated massive loperamide ingestions]. ( Carlsson, H; Höjer, J; Myllymäki, L; Westerbergh, J, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Myllymäki, L | 1 |
| Westerbergh, J | 1 |
| Carlsson, H | 1 |
| Höjer, J | 1 |
| de Lemos, ML | 1 |
| Guenter, J | 1 |
| Kletas, V | 1 |
1 review available for loperamide and Heart Diseases
| Article | Year |
|---|---|
Loperamide and cardiac events: Is high-dose use still safe for chemotherapy-induced diarrhea?
Topics: Antidiarrheals; Arrhythmias, Cardiac; Diarrhea; Dose-Response Relationship, Drug; Female; Heart Arre | 2018 |
1 other study available for loperamide and Heart Diseases
| Article | Year |
|---|---|
[Torsade de pointes following repeated massive loperamide ingestions].
Topics: Antidiarrheals; Arrhythmias, Cardiac; Electrocardiography; Heart Diseases; Humans; Long QT Syndrome; | 2020 |