Page last updated: 2024-10-30

loperamide and Gastroenteritis

loperamide has been researched along with Gastroenteritis in 18 studies

Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.

Gastroenteritis: INFLAMMATION of any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM. Causes of gastroenteritis are many including genetic, infection, HYPERSENSITIVITY, drug effects, and CANCER.

Research Excerpts

ExcerptRelevanceReference
"Our aim was to compare the efficacy and tolerability of loperamide and racecadotril in elderly patients with acute diarrhea."9.14Prospective randomized double-blind trial of racecadotril compared with loperamide in elderly people with gastroenteritis living in nursing homes. ( Colosimo, M; Cucchiara, S; Curto, LS; De Sarro, G; Falcone, D; Gallelli, L; Luberto, L; Marigliano, NM; Mazzei, F; Rende, P; Tolotta, GA, 2010)
"A 2-year-old girl was diagnosed as having acute gastroenteritis with severe diarrhoea, for which she was prescribed a loperamide solution."7.72[Ileus after the use of loperamide in a child with acute diarrhea]. ( Dudink, J; Mearin, LM; Sukhai, RN, 2003)
" Loperamide, in the dosage used in this study, appears to have no significant effect on the course of acute gastro-enteritis in early childhood."6.65Loperamide in the treatment of acute gastroenteritis in early childhood. Report of a two centre, double-blind, controlled clinical trial. ( Broadhead, R; Gangal, RN; Hendrickse, RG; Jaswal, OP; Owens, JR, 1981)
"Our aim was to compare the efficacy and tolerability of loperamide and racecadotril in elderly patients with acute diarrhea."5.14Prospective randomized double-blind trial of racecadotril compared with loperamide in elderly people with gastroenteritis living in nursing homes. ( Colosimo, M; Cucchiara, S; Curto, LS; De Sarro, G; Falcone, D; Gallelli, L; Luberto, L; Marigliano, NM; Mazzei, F; Rende, P; Tolotta, GA, 2010)
"In this systematic review, we present information relating to the effectiveness and safety of: rotavirus vaccines for the prevention of gastroenteritis; enteral rehydration solutions (oral or gastric), lactose-free feeds, loperamide, probiotics, and zinc for the treatment of gastroenteritis; and ondansetron for the treatment of vomiting."4.87Gastroenteritis in children. ( Dalby-Payne, JR; Elliott, EJ, 2011)
"A 2-year-old girl was diagnosed as having acute gastroenteritis with severe diarrhoea, for which she was prescribed a loperamide solution."3.72[Ileus after the use of loperamide in a child with acute diarrhea]. ( Dudink, J; Mearin, LM; Sukhai, RN, 2003)
" Loperamide, in the dosage used in this study, appears to have no significant effect on the course of acute gastro-enteritis in early childhood."2.65Loperamide in the treatment of acute gastroenteritis in early childhood. Report of a two centre, double-blind, controlled clinical trial. ( Broadhead, R; Gangal, RN; Hendrickse, RG; Jaswal, OP; Owens, JR, 1981)
"Loperamide was the only intervention with more side effects than STND [Quality: moderate]."2.58Comparative effectiveness and safety of interventions for acute diarrhea and gastroenteritis in children: A systematic review and network meta-analysis. ( Acosta-Reyes, J; Al Khalifah, R; Cuello-Garcia, C; Florez, ID; Foroutan, N; Granados, CM; Guyatt, GH; Pérez-Gaxiola, G; Sierra, JM; Thabane, L; Vernooij, RWM; Veroniki, AA; Yepes-Nuñez, JJ; Zea, AM; Zhang, Y, 2018)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19904 (22.22)18.7374
1990's2 (11.11)18.2507
2000's7 (38.89)29.6817
2010's4 (22.22)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Lee, AYS1
Smith, AJF1
Krummenacher, M1
Hughes, TL1
Florez, ID1
Veroniki, AA1
Al Khalifah, R1
Yepes-Nuñez, JJ1
Sierra, JM1
Vernooij, RWM1
Acosta-Reyes, J1
Granados, CM1
Pérez-Gaxiola, G1
Cuello-Garcia, C1
Zea, AM1
Zhang, Y1
Foroutan, N1
Guyatt, GH1
Thabane, L1
Gallelli, L1
Colosimo, M1
Tolotta, GA1
Falcone, D1
Luberto, L1
Curto, LS1
Rende, P1
Mazzei, F1
Marigliano, NM1
De Sarro, G1
Cucchiara, S1
Hofmann, R1
Dalby-Payne, JR1
Elliott, EJ1
Dalby-Payne, J5
Elliott, E5
Dudink, J1
Mearin, LM1
Sukhai, RN1
Eronen, M1
Putkonen, H1
Hallikainen, T1
Vartiainen, H1
Owens, JR1
Broadhead, R1
Hendrickse, RG1
Jaswal, OP1
Gangal, RN1
Tan, SH1
Tajima, T1
Maliukh, LS1
Kriklivets, IuI1
Iatskiv, MV1

Reviews

8 reviews available for loperamide and Gastroenteritis

ArticleYear
Comparative effectiveness and safety of interventions for acute diarrhea and gastroenteritis in children: A systematic review and network meta-analysis.
    PloS one, 2018, Volume: 13, Issue:12

    Topics: Antidiarrheals; Bayes Theorem; Child; Diarrhea; Gastroenteritis; Humans; Loperamide; Network Meta-An

2018
Gastroenteritis in children.
    BMJ clinical evidence, 2011, Jul-26, Volume: 2011

    Topics: Acute Disease; Administration, Oral; Child; Dehydration; Gastroenteritis; Humans; Incidence; Infant;

2011
Acute gastroenteritis in children.
    Clinical evidence, 2002, Issue:7

    Topics: Acute Disease; Child; Dehydration; Fluid Therapy; Gastroenteritis; Humans; Loperamide; Randomized Co

2002
Acute gastroenteritis in children.
    Clinical evidence, 2002, Issue:8

    Topics: Acute Disease; Child; Dehydration; Fluid Therapy; Gastroenteritis; Humans; Loperamide

2002
Gastroenteritis in children.
    Clinical evidence, 2003, Issue:10

    Topics: Acute Disease; Antidiarrheals; Child; Fluid Therapy; Gastroenteritis; Humans; Lactose; Loperamide

2003
Gastroenteritis in children.
    Clinical evidence, 2004, Issue:12

    Topics: Antidiarrheals; Child; Fluid Therapy; Gastroenteritis; Humans; Loperamide; Rehydration Solutions

2004
Gastroenteritis in children.
    Clinical evidence, 2005, Issue:13

    Topics: Antidiarrheals; Child; Fluid Therapy; Gastroenteritis; Humans; Intubation, Gastrointestinal; Loperam

2005
[Rotavirus infection].
    Ryoikibetsu shokogun shirizu, 1999, Issue:23 Pt 1

    Topics: Antidiarrheals; Fluid Therapy; Gastroenteritis; Humans; Infant; Loperamide; Rotavirus; Rotavirus Inf

1999

Trials

3 trials available for loperamide and Gastroenteritis

ArticleYear
Prospective randomized double-blind trial of racecadotril compared with loperamide in elderly people with gastroenteritis living in nursing homes.
    European journal of clinical pharmacology, 2010, Volume: 66, Issue:2

    Topics: Abdominal Pain; Aged; Aged, 80 and over; Aging; Antidiarrheals; Cytochrome P-450 Enzyme System; Dehy

2010
Loperamide in the treatment of acute gastroenteritis in early childhood. Report of a two centre, double-blind, controlled clinical trial.
    Annals of tropical paediatrics, 1981, Volume: 1, Issue:3

    Topics: Body Weight; Child, Preschool; Double-Blind Method; Drug Evaluation; Escherichia coli; Female; Gastr

1981
[Effectiveness of imodium in the treatment of patients with peptic ulcer and chronic gastroduodenitis associated with functional intestinal disorders].
    Klinicheskaia meditsina, 1986, Volume: 64, Issue:3

    Topics: Antidiarrheals; Clinical Trials as Topic; Diarrhea; Duodenitis; Gastroenteritis; Humans; Loperamide;

1986

Other Studies

7 other studies available for loperamide and Gastroenteritis

ArticleYear
An unusual case of loperamide anaphylaxis.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2020, Volume: 124, Issue:1

    Topics: Aged; Anaphylaxis; Antidiarrheals; Child; Cross Reactions; Drug Hypersensitivity; Epinephrine; Femal

2020
Remarks and questions on the article "Prospective randomized double-blind trial of racecadotril compared with loperamide in elderly people with gastroenteritis living in nursing homes".
    European journal of clinical pharmacology, 2010, Volume: 66, Issue:8

    Topics: Aged; Antidiarrheals; Double-Blind Method; Female; Gastroenteritis; Homes for the Aged; Humans; Lope

2010
[Ileus after the use of loperamide in a child with acute diarrhea].
    Nederlands tijdschrift voor geneeskunde, 2003, Apr-05, Volume: 147, Issue:14

    Topics: Antidiarrheals; Child, Preschool; Diarrhea; Electrolytes; Female; Fluid Therapy; Gastroenteritis; Hu

2003
Lethal gastroenteritis associated with clozapine and loperamide.
    The American journal of psychiatry, 2003, Volume: 160, Issue:12

    Topics: Adult; Antidiarrheals; Antipsychotic Agents; Bacillaceae Infections; Bacillus cereus; Clozapine; Dru

2003
Loperamide toxicity in an infant.
    Australian paediatric journal, 1983, Volume: 19, Issue:1

    Topics: Gastroenteritis; Humans; Infant; Loperamide; Male; Piperidines

1983
Aspirin or loperamide for childhood gastroenteritis.
    The Medical journal of Australia, 1980, Nov-29, Volume: 2, Issue:11

    Topics: Aspirin; Child; Gastroenteritis; Humans; Loperamide; Piperidines

1980
[Small intestinal perforation as a complication of treatment with loperamide in a Salmonella typhimurium infection].
    Nederlands tijdschrift voor geneeskunde, 1990, Oct-13, Volume: 134, Issue:41

    Topics: Female; Gastroenteritis; Humans; Intestinal Perforation; Loperamide; Salmonella Infections; Salmonel

1990