loperamide has been researched along with Escherichia coli Infections in 11 studies
Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.
Escherichia coli Infections: Infections with bacteria of the species ESCHERICHIA COLI.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recommended treatment for travelers' diarrhea includes the combination of an antibiotic, usually a fluoroquinolone or azithromycin, and loperamide for rapid resolution of symptoms." | 9.24 | Trial Evaluating Ambulatory Therapy of Travelers' Diarrhea (TrEAT TD) Study: A Randomized Controlled Trial Comparing 3 Single-Dose Antibiotic Regimens With Loperamide. ( Connor, P; Danboise, B; Fraser, J; Gutierrez, RL; Hulseberg, C; Hutley, EJ; Lalani, T; Porter, CK; Riddle, MS; Simons, MP; Swierczewski, B; Tribble, DR, 2017) |
| "The recommended treatment for traveler's diarrhea is the combination of an appropriate antibiotic (usually a fluoroquinolone) and loperamide." | 9.12 | Azithromycin and loperamide are comparable to levofloxacin and loperamide for the treatment of traveler's diarrhea in United States military personnel in Turkey. ( Frenck, RW; Johnston, JR; Monteville, MR; Putnam, SD; Riddle, MS; Rockabrand, DM; Sanders, JW; Tribble, DR; Ulukan, S, 2007) |
| "To determine the efficacy of loperamide given with long- and short-course quinolone therapy for treating traveler's diarrhea, 142 US military personnel were randomized to receive a single 750-mg dose of ciprofloxacin with placebo, 750 mg of ciprofloxacin with loperamide, or a 3-day course of 500 mg of ciprofloxacin twice daily with loperamide." | 9.07 | Treatment of traveler's diarrhea with ciprofloxacin and loperamide. ( DeFraites, R; Echeverria, P; Gelnett, J; Haberberger, RL; Murphy, GS; Petruccelli, BP; Sanchez, JL; Taylor, DN; Walz, S, 1992) |
| "To compare the safety and efficacy of loperamide used in combination with ciprofloxacin or ciprofloxacin alone for the treatment of travelers' diarrhea." | 9.07 | Treatment of travelers' diarrhea: ciprofloxacin plus loperamide compared with ciprofloxacin alone. A placebo-controlled, randomized trial. ( Candler, W; Echeverria, P; McQueen, C; Sanchez, JL; Taylor, DN; Thornton, S, 1991) |
| "Recommended treatment for travelers' diarrhea includes the combination of an antibiotic, usually a fluoroquinolone or azithromycin, and loperamide for rapid resolution of symptoms." | 5.24 | Trial Evaluating Ambulatory Therapy of Travelers' Diarrhea (TrEAT TD) Study: A Randomized Controlled Trial Comparing 3 Single-Dose Antibiotic Regimens With Loperamide. ( Connor, P; Danboise, B; Fraser, J; Gutierrez, RL; Hulseberg, C; Hutley, EJ; Lalani, T; Porter, CK; Riddle, MS; Simons, MP; Swierczewski, B; Tribble, DR, 2017) |
| "The recommended treatment for traveler's diarrhea is the combination of an appropriate antibiotic (usually a fluoroquinolone) and loperamide." | 5.12 | Azithromycin and loperamide are comparable to levofloxacin and loperamide for the treatment of traveler's diarrhea in United States military personnel in Turkey. ( Frenck, RW; Johnston, JR; Monteville, MR; Putnam, SD; Riddle, MS; Rockabrand, DM; Sanders, JW; Tribble, DR; Ulukan, S, 2007) |
| "To determine the efficacy of loperamide given with long- and short-course quinolone therapy for treating traveler's diarrhea, 142 US military personnel were randomized to receive a single 750-mg dose of ciprofloxacin with placebo, 750 mg of ciprofloxacin with loperamide, or a 3-day course of 500 mg of ciprofloxacin twice daily with loperamide." | 5.07 | Treatment of traveler's diarrhea with ciprofloxacin and loperamide. ( DeFraites, R; Echeverria, P; Gelnett, J; Haberberger, RL; Murphy, GS; Petruccelli, BP; Sanchez, JL; Taylor, DN; Walz, S, 1992) |
| "To compare the safety and efficacy of loperamide used in combination with ciprofloxacin or ciprofloxacin alone for the treatment of travelers' diarrhea." | 5.07 | Treatment of travelers' diarrhea: ciprofloxacin plus loperamide compared with ciprofloxacin alone. A placebo-controlled, randomized trial. ( Candler, W; Echeverria, P; McQueen, C; Sanchez, JL; Taylor, DN; Thornton, S, 1991) |
| "Dehydration is the most common complication." | 2.61 | Travelers' Diarrhea: A Clinical Review. ( Hon, KL; Leung, AAM; Leung, AKC; Wong, AHC, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Connor, BA | 1 |
| Martin, GJ | 1 |
| Riddle, MS | 3 |
| Connor, P | 1 |
| Fraser, J | 1 |
| Porter, CK | 1 |
| Swierczewski, B | 1 |
| Hutley, EJ | 1 |
| Danboise, B | 1 |
| Simons, MP | 1 |
| Hulseberg, C | 1 |
| Lalani, T | 1 |
| Gutierrez, RL | 1 |
| Tribble, DR | 2 |
| Leung, AKC | 1 |
| Leung, AAM | 1 |
| Wong, AHC | 1 |
| Hon, KL | 1 |
| Sanders, JW | 1 |
| Frenck, RW | 1 |
| Putnam, SD | 1 |
| Johnston, JR | 1 |
| Ulukan, S | 1 |
| Rockabrand, DM | 1 |
| Monteville, MR | 1 |
| Nelson, JM | 1 |
| Griffin, PM | 1 |
| Jones, TF | 1 |
| Smith, KE | 1 |
| Scallan, E | 1 |
| Petruccelli, BP | 1 |
| Murphy, GS | 1 |
| Sanchez, JL | 2 |
| Walz, S | 1 |
| DeFraites, R | 1 |
| Gelnett, J | 1 |
| Haberberger, RL | 1 |
| Echeverria, P | 2 |
| Taylor, DN | 2 |
| Candler, W | 1 |
| Thornton, S | 1 |
| McQueen, C | 1 |
| Du Pont, HL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Double-Blind, Clinical Trial Evaluating Three Single Dose Regimens With Loperamide for Treatment of Ambulatory Watery Travelers' Diarrhea, and Azithromycin With and Without Loperamide for Treatment of Ambulatory Dysentery/Febrile Diarrhea[NCT01618591] | 384 participants (Actual) | Interventional | 2012-09-30 | Terminated (stopped due to AWD arm was completed. ADF diarrhea arm was unable to fill completely and there are no funds remaining to continue recruiting/enrolling.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for loperamide and Escherichia coli Infections
| Article | Year |
|---|---|
Travelers' Diarrhea: A Clinical Review.
Topics: Anti-Bacterial Agents; Azithromycin; Bismuth; Dehydration; Developing Countries; Dysentery; Escheric | 2019 |
Nonfluid therapy and selected chemoprophylaxis of acute diarrhea.
Topics: Acute Disease; Adult; Anti-Infective Agents; Bismuth; Campylobacter Infections; Child; Child, Presch | 1985 |
5 trials available for loperamide and Escherichia coli Infections
| Article | Year |
|---|---|
Trial Evaluating Ambulatory Therapy of Travelers' Diarrhea (TrEAT TD) Study: A Randomized Controlled Trial Comparing 3 Single-Dose Antibiotic Regimens With Loperamide.
Topics: Acute Disease; Adult; Afghanistan; Anti-Bacterial Agents; Azithromycin; Diarrhea; Djibouti; Double-B | 2017 |
Azithromycin and loperamide are comparable to levofloxacin and loperamide for the treatment of traveler's diarrhea in United States military personnel in Turkey.
Topics: Adult; Azithromycin; Campylobacter Infections; Diarrhea; Double-Blind Method; Drug Therapy, Combinat | 2007 |
Treatment of traveler's diarrhea with ciprofloxacin and loperamide.
Topics: Campylobacter Infections; Ciprofloxacin; Diarrhea; Double-Blind Method; Drug Therapy, Combination; D | 1992 |
Treatment of travelers' diarrhea: ciprofloxacin plus loperamide compared with ciprofloxacin alone. A placebo-controlled, randomized trial.
Topics: Ciprofloxacin; Diarrhea; Double-Blind Method; Drug Therapy, Combination; Dysentery, Bacillary; Esche | 1991 |
Nonfluid therapy and selected chemoprophylaxis of acute diarrhea.
Topics: Acute Disease; Adult; Anti-Infective Agents; Bismuth; Campylobacter Infections; Child; Child, Presch | 1985 |
5 other studies available for loperamide and Escherichia coli Infections
| Article | Year |
|---|---|
Use of the Multiplex Diagnostic PCR Panel in Diarrheal Disease: Expert Guidance on the Interpretation of Results With a Focus on Travelers' Diarrhea.
Topics: Anti-Bacterial Agents; Antidiarrheals; Antiprotozoal Agents; Bismuth; Campylobacter Infections; Dyse | 2020 |
Treatment and prevention of traveler's diarrhea.
Topics: Antidiarrheals; Diarrhea; Escherichia coli Infections; Female; Fluid Therapy; Foodborne Diseases; Hu | 2015 |
Antimicrobial and antimotility agent use in persons with shiga toxin-producing Escherichia coli O157 infection in FoodNet Sites.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Case-Control Studies; Child; Child, Preschool; Diphenoxyla | 2011 |
Advice for travelers.
Topics: Anti-Infective Agents; Antidiarrheals; Bacterial Vaccines; Cholera; Ciprofloxacin; Diarrhea; Diphthe | 1998 |
Advice for travelers.
Topics: Antibiotic Prophylaxis; Bacterial Vaccines; Diarrhea; Diphtheria-Tetanus-Pertussis Vaccine; Escheric | 1999 |