Page last updated: 2024-10-30
loperamide and Encephalopathy, Toxic
loperamide has been researched along with Encephalopathy, Toxic in 1 studies
Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|
| "Loperamide (LOP) is a peripherally acting opioid receptor agonist used for the management of chronic diarrhea through the reduction of gut motility." | 2.71 | Interaction of ritonavir-boosted tipranavir with loperamide does not result in loperamide-associated neurologic side effects in healthy volunteers. ( Heming, T; Hoelscher, D; Johnson, P; Kavanaugh, K; Legg, D; MacGregor, T; McCallister, S; Mukwaya, G; Sabo, JP, 2005) |
Research
Studies (1)
| Timeframe | Studies, this research(%) | All Research% |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|
| Mukwaya, G | 1 |
| MacGregor, T | 1 |
| Hoelscher, D | 1 |
| Heming, T | 1 |
| Legg, D | 1 |
| Kavanaugh, K | 1 |
| Johnson, P | 1 |
| Sabo, JP | 1 |
| McCallister, S | 1 |
Clinical Trials (1)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status |
|---|
| An Open-label, Randomized, Fasting, Two-period, Single-dose, Crossover Study to Assess Bioequivalence Between a Combination Caplet With Loperamide Hydrochloride and Simethicone (Janssen-Cilag, France), and Imodium® Express Tablets-lyophilizate (Janssen-Ci[NCT04186936] | Phase 1 | 48 participants (Actual) | Interventional | 2019-12-05 | Completed |
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Trials
1 trial available for loperamide and Encephalopathy, Toxic