loperamide has been researched along with Emesis in 11 studies
Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objectives of this prospective non-concurrent cohort study were to confirm the efficacy of vaginal misoprostol for early pregnancy termination and to determine whether the incidence of side effects is lower with prophylactic loperamide and acetaminophen." | 9.09 | Early pregnancy termination with vaginal misoprostol combined with loperamide and acetaminophen prophylaxis. ( Harwood, B; Jain, JK; Meckstroth, KR; Mishell, DR, 2001) |
| "Loperamide, an opiate receptor agonist, commonly used in the treatment of diarrhoea, reliably induced emesis in the ferret, when given subcutaneously." | 7.68 | The neuropharmacology of loperamide-induced emesis in the ferret: the role of the area postrema, vagus, opiate and 5-HT3 receptors. ( Andrews, PL; Bhandari, P; Bingham, S, 1992) |
| "Previous studies of the mechanism of zacopride-induced emesis in ferrets have concluded that it is mediated predominantly by an antagonist effect on 5-HT3 receptors although the possibility of a contribution from an agonist effect at 5-HT4 receptors was not excluded." | 7.68 | Preliminary evidence for the involvement of the putative 5-HT4 receptor in zacopride- and copper sulphate-induced vomiting in the ferret. ( Andrews, PL; Bhandari, P, 1991) |
| "The objectives of this prospective non-concurrent cohort study were to confirm the efficacy of vaginal misoprostol for early pregnancy termination and to determine whether the incidence of side effects is lower with prophylactic loperamide and acetaminophen." | 5.09 | Early pregnancy termination with vaginal misoprostol combined with loperamide and acetaminophen prophylaxis. ( Harwood, B; Jain, JK; Meckstroth, KR; Mishell, DR, 2001) |
| " Nicotine, however, dose dependently induced vomiting in the Suncus with an ED50 of 8." | 3.69 | Absence of emetic effects of morphine and loperamide in Suncus murinus. ( Friderichs, E; Reimann, W; Reinartz, S; Selve, N, 1994) |
| " reduced retching and vomiting elicited by loperamide, copper sulfate, ipecac syrup and cisplatin in a dose-dependent manner." | 3.69 | Broad spectrum antiemetic effects of CP-122,721, a tachykinin NK1 receptor antagonist, in ferrets. ( Ashton, C; Gonsalves, S; Watson, J, 1996) |
| ")-induced emesis in ferrets and substantially decreased loperamide (0." | 3.68 | Resinferatoxin, an ultrapotent capsaicin analogue, has anti-emetic properties in the ferret. ( Andrews, PL; Bhandari, P, 1993) |
| "Loperamide, an opiate receptor agonist, commonly used in the treatment of diarrhoea, reliably induced emesis in the ferret, when given subcutaneously." | 3.68 | The neuropharmacology of loperamide-induced emesis in the ferret: the role of the area postrema, vagus, opiate and 5-HT3 receptors. ( Andrews, PL; Bhandari, P; Bingham, S, 1992) |
| "Previous studies of the mechanism of zacopride-induced emesis in ferrets have concluded that it is mediated predominantly by an antagonist effect on 5-HT3 receptors although the possibility of a contribution from an agonist effect at 5-HT4 receptors was not excluded." | 3.68 | Preliminary evidence for the involvement of the putative 5-HT4 receptor in zacopride- and copper sulphate-induced vomiting in the ferret. ( Andrews, PL; Bhandari, P, 1991) |
| "To evaluate the efficacy of maropitant and loperamide for the prevention and reduction of adverse gastrointestinal effects associated with administration of paclitaxel to dogs with cancer." | 2.90 | Assessment of the administration of maropitant and loperamide to dogs with cancer for the prevention and reduction of adverse effects associated with the administration of paclitaxel. ( Cartagena-Albertus, JC; Engel Manchado, J; Moise, A; Montoya Alonso, JA; Moya García, S, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cartagena-Albertus, JC | 1 |
| Engel Manchado, J | 1 |
| Moise, A | 1 |
| Moya García, S | 1 |
| Montoya Alonso, JA | 1 |
| Percie du Sert, N | 1 |
| Rudd, JA | 1 |
| Moss, R | 1 |
| Andrews, PL | 6 |
| Kassem, AS | 1 |
| Madkour, AA | 1 |
| Massoud, BZ | 1 |
| Mehanna, ZM | 1 |
| Selve, N | 1 |
| Friderichs, E | 1 |
| Reimann, W | 1 |
| Reinartz, S | 1 |
| Bhandari, P | 3 |
| Gonsalves, S | 1 |
| Watson, J | 1 |
| Ashton, C | 1 |
| Richards, CA | 1 |
| Carr, D | 1 |
| Spitz, L | 1 |
| Milla, PJ | 1 |
| Zaman, S | 1 |
| Woods, AJ | 1 |
| Watson, JW | 1 |
| Reynolds, DJ | 1 |
| Jain, JK | 1 |
| Harwood, B | 1 |
| Meckstroth, KR | 1 |
| Mishell, DR | 1 |
| Bingham, S | 1 |
3 trials available for loperamide and Emesis
| Article | Year |
|---|---|
Assessment of the administration of maropitant and loperamide to dogs with cancer for the prevention and reduction of adverse effects associated with the administration of paclitaxel.
Topics: Animals; Antidiarrheals; Antiemetics; Antineoplastic Agents, Phytogenic; Diarrhea; Dog Diseases; Dog | 2019 |
Loperamide in acute childhood diarrhoea: a double blind controlled trial.
Topics: Clinical Trials as Topic; Dehydration; Diarrhea, Infantile; Double-Blind Method; Feces; Humans; Infa | 1983 |
Early pregnancy termination with vaginal misoprostol combined with loperamide and acetaminophen prophylaxis.
Topics: Abortifacient Agents, Nonsteroidal; Abortion, Induced; Acetaminophen; Administration, Intravaginal; | 2001 |
8 other studies available for loperamide and Emesis
| Article | Year |
|---|---|
The delayed phase of cisplatin-induced emesis is mediated by the area postrema and not the abdominal visceral innervation in the ferret.
Topics: Abdomen; Animals; Antineoplastic Agents; Apomorphine; Area Postrema; Castration; Cisplatin; Drinking | 2009 |
Absence of emetic effects of morphine and loperamide in Suncus murinus.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Injections, Intraperitone | 1994 |
Resinferatoxin, an ultrapotent capsaicin analogue, has anti-emetic properties in the ferret.
Topics: Animals; Antiemetics; Behavior, Animal; Blood Pressure; Body Temperature; Capsaicin; Copper; Copper | 1993 |
Broad spectrum antiemetic effects of CP-122,721, a tachykinin NK1 receptor antagonist, in ferrets.
Topics: Animals; Antiemetics; Cisplatin; Copper Sulfate; Emetics; Ferrets; Ipecac; Loperamide; Male; Neuroki | 1996 |
Nissen-type fundoplication and its effects on the emetic reflex and gastric motility in the ferret.
Topics: Animals; Antidiarrheals; Atropine; Behavior, Animal; Disease Models, Animal; Electric Stimulation; F | 2000 |
The effect of the NK1 receptor antagonist CP-99,994 on emesis and c-fos protein induction by loperamide in the ferret.
Topics: Animals; Antidiarrheals; Brain Stem; Female; Ferrets; Loperamide; Male; Neurokinin-1 Receptor Antago | 2000 |
The neuropharmacology of loperamide-induced emesis in the ferret: the role of the area postrema, vagus, opiate and 5-HT3 receptors.
Topics: Animals; Behavior, Animal; Cerebral Ventricles; Domperidone; Female; Fenclonine; Ferrets; Loperamide | 1992 |
Preliminary evidence for the involvement of the putative 5-HT4 receptor in zacopride- and copper sulphate-induced vomiting in the ferret.
Topics: Analysis of Variance; Animals; Antiemetics; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo C | 1991 |