loperamide has been researched along with Drug Withdrawal Symptoms in 14 studies
Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "With the increasing amount of information available on the Internet describing techniques for using loperamide either for self-treatment of opioid withdrawal syndromes or for recreational use (so-called legal highs), the objective was to describe a statewide poison control system's experience with loperamide misuse and abuse, with specific interest in cases of cardiotoxicity, and to determine if reported loperamide misuse or abuse cases have recently increased." | 3.85 | Loperamide Trends in Abuse and Misuse Over 13 Years: 2002-2015. ( Cantrell, FL; Corbett, B; Koh, CH; Lasoff, DR; Minns, AB, 2017) |
| "Loperamide is a peripheral mu-opioid agonist that is intended to be used for diarrhea." | 1.56 | Long-term Buprenorphine Treatment for Loperamide Use Disorder: A Case Series. ( Allgaier, JT; Brar, JK; Broyan, VR; Nye, L; Saxon, AJ, 2020) |
| "Loperamide is a readily accessible nonprescription medication that is increasingly being used surreptitiously as an opioid substitute to alleviate the symptoms of acute opioid withdrawal." | 1.51 | Loperamide misuse to avoid opioid withdrawal and to achieve a euphoric effect: high doses and high risk. ( Alexander, A; Brent, J; Calello, DP; Campleman, S; Lee, VR; Nelson, LS; Ruck, B; Vera, A; Wax, P, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (21.43) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Hill, MR | 1 |
| Hopkins, MR | 1 |
| Knezevic, CE | 1 |
| Brar, JK | 1 |
| Broyan, VR | 1 |
| Allgaier, JT | 1 |
| Nye, L | 1 |
| Saxon, AJ | 1 |
| Heeren, N | 1 |
| Farver, D | 1 |
| Lee, VR | 1 |
| Vera, A | 1 |
| Alexander, A | 1 |
| Ruck, B | 1 |
| Nelson, LS | 1 |
| Wax, P | 1 |
| Campleman, S | 1 |
| Brent, J | 1 |
| Calello, DP | 1 |
| Ward, HB | 1 |
| Barnett, BS | 1 |
| Suzuki, J | 1 |
| White, CM | 1 |
| Kim, S | 1 |
| Lasoff, DR | 1 |
| Koh, CH | 1 |
| Corbett, B | 1 |
| Minns, AB | 1 |
| Cantrell, FL | 1 |
| Daniulaityte, R | 1 |
| Carlson, R | 1 |
| Falck, R | 1 |
| Cameron, D | 1 |
| Perera, S | 1 |
| Chen, L | 1 |
| Sheth, A | 1 |
| Korey, A | 1 |
| Zilm, DH | 1 |
| Sellers, EM | 1 |
| De Luca, A | 1 |
| Coupar, IM | 2 |
| Yanagita, T | 1 |
| Miyasato, K | 1 |
| Sato, J | 1 |
| Hill, MA | 1 |
| Greason, FC | 1 |
4 reviews available for loperamide and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Loperamide: A Readily Available but Dangerous Opioid Substitute.
Topics: Analgesics, Opioid; Animals; Antidiarrheals; Humans; Loperamide; Naloxone; Substance Withdrawal Synd | 2019 |
The unsuspected threat of three opioid-like substitutes.
Topics: Analgesics; Antidiarrheals; Gabapentin; Humans; Loperamide; Mitragyna; Opiate Substitution Treatment | 2019 |
Insights into opioid action in the intestinal tract.
Topics: Analgesics, Opioid; Animals; Antidiarrheals; Constipation; Diarrhea; Gastrointestinal Motility; Guin | 1996 |
Opioid action of the intestine: the importance of the intestinal mucosa.
Topics: Antidiarrheals; Body Water; Diarrhea; Diphenoxylate; Humans; Intestinal Mucosa; Intestines; Loperami | 1987 |
1 trial available for loperamide and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
"I just wanted to tell you that loperamide WILL WORK": a web-based study of extra-medical use of loperamide.
Topics: Advertising; Analgesics, Opioid; Humans; Internet; Loperamide; Opioid-Related Disorders; Self Care; | 2013 |
9 other studies available for loperamide and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Emerging Toxidromes: A 25-Year-Old Woman with Syncope and ECG Changes.
Topics: Adult; Electrocardiography; Female; Humans; Loperamide; Opioid-Related Disorders; Oxycodone; Self Me | 2019 |
Long-term Buprenorphine Treatment for Loperamide Use Disorder: A Case Series.
Topics: Analgesics, Opioid; Buprenorphine; Humans; Loperamide; Opioid-Related Disorders; Substance Withdrawa | 2020 |
You Abused What? Getting High with Unique Medications.
Topics: Amines; Anticonvulsants; Antidiarrheals; Antipsychotic Agents; Antitussive Agents; Cyclohexanecarbox | 2017 |
Loperamide misuse to avoid opioid withdrawal and to achieve a euphoric effect: high doses and high risk.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidiarrheals; Arrhythmias, Cardiac; Atrioventricular B | 2019 |
Rapid transition from methadone to buprenorphine using naltrexone-induced withdrawal: A case report.
Topics: Adult; Antidiarrheals; Antiemetics; Antipruritics; Buprenorphine; Clonidine; Deprescriptions; Drug S | 2019 |
Loperamide Trends in Abuse and Misuse Over 13 Years: 2002-2015.
Topics: Antidiarrheals; Cardiotoxicity; Databases, Factual; Dose-Response Relationship, Drug; Humans; Lopera | 2017 |
Dependence liability of two antidiarrheals, nufenoxole and loperamide.
Topics: Adult; Antidiarrheals; Body Temperature; Electromyography; Humans; Loperamide; Male; Naloxone; Oxadi | 1980 |
Dependence potential of loperamide studied in rhesus monkeys.
Topics: Administration, Oral; Animals; Behavior, Animal; Female; Haplorhini; Humans; Injections, Intravenous | 1979 |
Loperamide dependence.
Topics: Adult; Diarrhea; Humans; Loperamide; Male; Substance Withdrawal Syndrome; Substance-Related Disorder | 1992 |