loperamide has been researched along with Disease Exacerbation in 3 studies
Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The incidence of severe diarrhea is reduced by using a starting dose of irinotecan 125 mg/m2 and by initiating loperamide at the earliest signs of diarrhea." | 9.08 | Phase II trial of irinotecan in patients with progressive or rapidly recurrent colorectal cancer. ( Burris, HA; Eckardt, JR; Eckhardt, SG; Elfring, GL; Hilsenbeck, SG; Kuhn, JG; Nelson, J; Rinaldi, DA; Rodriguez, GI; Rothenberg, ML; Schaaf, LJ; Smith, LS; Thurman, AM; Von Hoff, DD; Weiss, GR, 1996) |
| " The incidence of severe diarrhea is reduced by using a starting dose of irinotecan 125 mg/m2 and by initiating loperamide at the earliest signs of diarrhea." | 5.08 | Phase II trial of irinotecan in patients with progressive or rapidly recurrent colorectal cancer. ( Burris, HA; Eckardt, JR; Eckhardt, SG; Elfring, GL; Hilsenbeck, SG; Kuhn, JG; Nelson, J; Rinaldi, DA; Rodriguez, GI; Rothenberg, ML; Schaaf, LJ; Smith, LS; Thurman, AM; Von Hoff, DD; Weiss, GR, 1996) |
| "The development of toxic megacolon as a sequel of infectious colitis is rare." | 1.31 | Campylobacter jejuni-induced severe colitis--a rare cause of toxic megacolon. ( Gerken, G; Peitgen, K; Rünzi, M; Schneider, A; von Birgelen, C, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aouinti, I | 1 |
| Kaabi, W | 1 |
| Charfi, O | 1 |
| Lakhoua, G | 1 |
| Hamza, I | 1 |
| Daghfous, R | 1 |
| El Aidli, S | 1 |
| Kastalli, S | 1 |
| Zaiem, A | 1 |
| Rothenberg, ML | 1 |
| Eckardt, JR | 1 |
| Kuhn, JG | 1 |
| Burris, HA | 1 |
| Nelson, J | 1 |
| Hilsenbeck, SG | 1 |
| Rodriguez, GI | 1 |
| Thurman, AM | 1 |
| Smith, LS | 1 |
| Eckhardt, SG | 1 |
| Weiss, GR | 1 |
| Elfring, GL | 1 |
| Rinaldi, DA | 1 |
| Schaaf, LJ | 1 |
| Von Hoff, DD | 1 |
| Schneider, A | 1 |
| Rünzi, M | 1 |
| Peitgen, K | 1 |
| von Birgelen, C | 1 |
| Gerken, G | 1 |
1 trial available for loperamide and Disease Exacerbation
| Article | Year |
|---|---|
Phase II trial of irinotecan in patients with progressive or rapidly recurrent colorectal cancer.
Topics: Adenocarcinoma; Antidiarrheals; Antineoplastic Agents, Phytogenic; Camptothecin; Colorectal Neoplasm | 1996 |
2 other studies available for loperamide and Disease Exacerbation
| Article | Year |
|---|---|
Community-acquired pseudomembranous colitis precipitated by loperamide.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Community-Acquired Infectio | 2019 |
Campylobacter jejuni-induced severe colitis--a rare cause of toxic megacolon.
Topics: Adult; Campylobacter Infections; Campylobacter jejuni; Colectomy; Colitis; Disease Progression; Huma | 2000 |