loperamide has been researched along with Cystic Fibrosis of Pancreas in 4 studies
Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Oral DRAinh-A250 and tenapanor comparably reduced signs of constipation in loperamide-treated mice, with additive effects found on coadministration." | 3.88 | SLC26A3 inhibitor identified in small molecule screen blocks colonic fluid absorption and reduces constipation. ( Cil, O; Haggie, PM; Lee, S; Phuan, PW; Rivera, AA; Tan, JA; Verkman, AS, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Haggie, PM | 1 |
| Cil, O | 1 |
| Lee, S | 1 |
| Tan, JA | 1 |
| Rivera, AA | 1 |
| Phuan, PW | 1 |
| Verkman, AS | 1 |
| Hardcastle, J | 1 |
| Hardcastle, PT | 1 |
| Taylor, CJ | 3 |
| Ghosal, S | 2 |
| McGaw, J | 1 |
| Colledge, WH | 1 |
| Ratcliff, R | 1 |
| Evans, MJ | 1 |
4 other studies available for loperamide and Cystic Fibrosis of Pancreas
| Article | Year |
|---|---|
SLC26A3 inhibitor identified in small molecule screen blocks colonic fluid absorption and reduces constipation.
Topics: Animals; Antiporters; Chloride-Bicarbonate Antiporters; Chlorides; Constipation; Cystic Fibrosis; Di | 2018 |
Loperamide inhibits the enhanced intestinal glucose absorption of cystic fibrosis in vitro.
Topics: Adolescent; Child; Child, Preschool; Cystic Fibrosis; Glucose; Humans; In Vitro Techniques; Infant; | 1994 |
Modification of nasal membrane potential difference with inhaled amiloride and loperamide in the cystic fibrosis (CF) mouse.
Topics: Amiloride; Animals; Cystic Fibrosis; Dose-Response Relationship, Drug; Female; Loperamide; Male; Mem | 1996 |
Sodium channel blockers and uridine triphosphate: effects on nasal potential difference in cystic fibrosis mice.
Topics: Amiloride; Animals; Chlorides; Cystic Fibrosis; Drug Therapy, Combination; Loperamide; Membrane Pote | 2000 |