loperamide has been researched along with Colonic Neoplasms in 3 studies
Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eighty patients with diarrhea after colorectal cancer surgery were randomized into two groups equally, the control group were treated with imodium (loperamide hydrochloride) and the treatment group treated by BYP combined with imodium." | 5.13 | [Clinical efficacy of buzhong yiqi pill combined with imodium in treating post-operational diarrhea in patients of colonic cancer]. ( Chen, ZY; Tu, XH, 2008) |
| " Efficacy endpoints were incidence and severity of radiation-induced diarrhea, daily number of bowel movements, and the time from the start of the study to the use of loperamide as rescue medication." | 5.12 | Use of probiotics for prevention of radiation-induced diarrhea. ( De Renzis, C; Delia, P; Donato, V; Famularo, G; Frosina, P; Messina, G; Sansotta, G, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, IY | 1 |
| Shim, MJ | 1 |
| Lee, DM | 1 |
| Lee, AR | 1 |
| Kim, MA | 1 |
| Yoon, MJ | 1 |
| Kwon, MR | 1 |
| Lee, HI | 1 |
| Seo, MJ | 1 |
| Choi, YW | 1 |
| Choi, KS | 1 |
| Tu, XH | 1 |
| Chen, ZY | 1 |
| Delia, P | 1 |
| Sansotta, G | 1 |
| Donato, V | 1 |
| Frosina, P | 1 |
| Messina, G | 1 |
| De Renzis, C | 1 |
| Famularo, G | 1 |
2 trials available for loperamide and Colonic Neoplasms
| Article | Year |
|---|---|
[Clinical efficacy of buzhong yiqi pill combined with imodium in treating post-operational diarrhea in patients of colonic cancer].
Topics: Adult; Aged; Colonic Neoplasms; Diarrhea; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; | 2008 |
Use of probiotics for prevention of radiation-induced diarrhea.
Topics: Antidiarrheals; Colonic Neoplasms; Diarrhea; Dose-Response Relationship, Drug; Double-Blind Method; | 2007 |
1 other study available for loperamide and Colonic Neoplasms
| Article | Year |
|---|---|
Loperamide overcomes the resistance of colon cancer cells to bortezomib by inducing CHOP-mediated paraptosis-like cell death.
Topics: Antidiarrheals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bo | 2019 |