loperamide has been researched along with Cardiomyopathy, Hypertrophic in 1 studies
Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.
Cardiomyopathy, Hypertrophic: A form of CARDIAC MUSCLE disease, characterized by left and/or right ventricular hypertrophy (HYPERTROPHY, LEFT VENTRICULAR; HYPERTROPHY, RIGHT VENTRICULAR), frequent asymmetrical involvement of the HEART SEPTUM, and normal or reduced left ventricular volume. Risk factors include HYPERTENSION; AORTIC STENOSIS; and gene MUTATION; (FAMILIAL HYPERTROPHIC CARDIOMYOPATHY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Loperamide, a μ-opioid receptor agonist, can cause cardiotoxicity by inhibiting the potassium ion channel and slowing cardiomyocyte repolarization." | 4.02 | Loperamide Toxicity Revealing Apical Hypertrophic Cardiomyopathy. ( Chitturi, KR; Clewing, M; Hatcher, C; Khan, N; Nagueh, SF, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khan, N | 1 |
| Chitturi, KR | 1 |
| Hatcher, C | 1 |
| Clewing, M | 1 |
| Nagueh, SF | 1 |
1 other study available for loperamide and Cardiomyopathy, Hypertrophic
| Article | Year |
|---|---|
Loperamide Toxicity Revealing Apical Hypertrophic Cardiomyopathy.
Topics: Adult; Antidiarrheals; Cardiomyopathy, Hypertrophic; Cardiotoxicity; DNA Mutational Analysis; Electr | 2021 |