Page last updated: 2024-10-30

loperamide and Brugada Syndrome

loperamide has been researched along with Brugada Syndrome in 2 studies

Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.

Brugada Syndrome: An autosomal dominant defect of cardiac conduction that is characterized by an abnormal ST-segment in leads V1-V3 on the ELECTROCARDIOGRAM resembling a right BUNDLE-BRANCH BLOCK; high risk of VENTRICULAR TACHYCARDIA; or VENTRICULAR FIBRILLATION; SYNCOPAL EPISODE; and possible sudden death. This syndrome is linked to mutations of gene encoding the cardiac SODIUM CHANNEL alpha subunit.

Research Excerpts

ExcerptRelevanceReference
"We present the case of a 14-year-old boy with obesity, hypertension, and chronic loperamide abuse who presented to our facility with symptoms of opioid withdrawal and type 1 Brugada pattern on an electrocardiogram."7.88Brugada Syndrome Associated With Adolescent Loperamide Abuse. ( Cohen, M; Stefek, B; Wolfe, LT, 2018)
"We present the case of a 14-year-old boy with obesity, hypertension, and chronic loperamide abuse who presented to our facility with symptoms of opioid withdrawal and type 1 Brugada pattern on an electrocardiogram."3.88Brugada Syndrome Associated With Adolescent Loperamide Abuse. ( Cohen, M; Stefek, B; Wolfe, LT, 2018)
"Loperamide has been increasing in popularity recently for its effects separate from treatment of diarrhea."1.48Brugada-Type Pattern on Electrocardiogram Associated with High-Dose Loperamide Abuse. ( Brice, JA; Clark, RF; Sun, C, 2018)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sun, C1
Brice, JA1
Clark, RF1
Stefek, B1
Wolfe, LT1
Cohen, M1

Other Studies

2 other studies available for loperamide and Brugada Syndrome

ArticleYear
Brugada-Type Pattern on Electrocardiogram Associated with High-Dose Loperamide Abuse.
    The Journal of emergency medicine, 2018, Volume: 54, Issue:4

    Topics: Brugada Syndrome; Electrocardiography; Humans; Loperamide; Male; Middle Aged; Substance-Related Diso

2018
Brugada Syndrome Associated With Adolescent Loperamide Abuse.
    Pediatrics, 2018, Volume: 142, Issue:4

    Topics: Adolescent; Analgesics, Opioid; Antidiarrheals; Brugada Syndrome; Humans; Loperamide; Male; Mutation

2018