loperamide has been researched along with Bowel Diseases, Inflammatory in 6 studies
Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Loperamide has a relaxing effect on localized and segmental large-bowel spasms." | 2.68 | A double-blind placebo-controlled trial with loperamide in irritable bowel syndrome. ( Bernklev, T; Efskind, PS; Vatn, MH, 1996) |
| "When treating diarrhea, physicians need to control inflammatory activity using appropriate treatment algorithms." | 2.44 | Treatment of diarrhea in patients with inflammatory bowel disease: concepts and cautions. ( Hanauer, SB; Shah, SB, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Selby, A | 1 |
| Reichenbach, ZW | 1 |
| Piech, G | 1 |
| Friedenberg, FK | 1 |
| Twardowska, A | 1 |
| Fichna, J | 1 |
| Binienda, A | 1 |
| Major, GAD | 1 |
| Gunn, D | 1 |
| Hanauer, SB | 2 |
| Shah, SB | 1 |
| Efskind, PS | 1 |
| Bernklev, T | 1 |
| Vatn, MH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Double Blind, Placebo Controlled, Cross Over Study to Investigate the Effectiveness and Safety of Eluxadoline in the Treatment of Diabetic Diarrhea[NCT04313088] | Phase 2/Phase 3 | 0 participants (Actual) | Interventional | 2022-07-01 | Withdrawn (stopped due to This study did not enroll any subjects) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for loperamide and Bowel Diseases, Inflammatory
| Article | Year |
|---|---|
Pathophysiology, Differential Diagnosis, and Treatment of Diabetic Diarrhea.
Topics: Antidiarrheals; Autonomic Nervous System Diseases; Blind Loop Syndrome; Celiac Disease; Diabetes Mel | 2019 |
Enkephalinases as a new pharmacological target in the treatment of gastrointestinal tract disorders
Topics: Antidiarrheals; Diarrhea; Gastrointestinal Diseases; Humans; Inflammatory Bowel Diseases; Irritable | 2020 |
Chronic diarrhoea in adults: what not to miss.
Topics: Adenocarcinoma; Adenoma; Antidiarrheals; Bile Acids and Salts; Celiac Disease; Chronic Disease; Colo | 2019 |
Treatment of diarrhea in patients with inflammatory bowel disease: concepts and cautions.
Topics: Animals; Antidiarrheals; Colitis, Ulcerative; Crohn Disease; Diarrhea; Gastrointestinal Transit; Hum | 2007 |
1 trial available for loperamide and Bowel Diseases, Inflammatory
| Article | Year |
|---|---|
A double-blind placebo-controlled trial with loperamide in irritable bowel syndrome.
Topics: Adult; Antidiarrheals; Double-Blind Method; Female; Humans; Inflammatory Bowel Diseases; Loperamide; | 1996 |
1 other study available for loperamide and Bowel Diseases, Inflammatory
| Article | Year |
|---|---|
The benefits of loperamide in the treatment of patients with IBS or IBD. Introduction.
Topics: Antidiarrheals; Humans; Inflammatory Bowel Diseases; Irritable Bowel Syndrome; Loperamide | 2007 |