loperamide has been researched along with Body Weight in 19 studies
Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study was undertaken to assess SHTC relieved effects on the clinical symptoms of loperamide (LOP) induced constipation in Sprague Dawley (SD) rat model and to clarify the relationship between the protective effect of SHTC on constipation and the gut microbiota." | 8.12 | Chinese patent medicine shouhui tongbian capsule attenuated loperamide-induced constipation through modulating the gut microbiota in rat. ( Erhunmwunsee, F; Li, B; Lin, Q; Liu, M; Mou, Y; Tian, J; Wang, S; Zhang, G, 2022) |
| " platyphylla, alterations in excretion parameters, histological structure, mucin secretion, and related protein levels were investigated in rats with loperamide (Lop)-induced constipation after treatment with aqueous extract of L." | 7.79 | Aqueous extracts of Liriope platyphylla induced significant laxative effects on loperamide-induced constipation of SD rats. ( Hong, JT; Hwang, DY; Kim, JE; Ko, J; Kwak, MH; Lee, YJ, 2013) |
| " Loperamide (2 mg/kg, twice per day) was injected intraperitoneally to induce constipation in the four experimental groups." | 7.78 | Effects of Ficus carica paste on loperamide-induced constipation in rats. ( Back, HI; Chae, HJ; Chae, SW; Ha, KC; Hwang, MH; Im, YJ; Jeon, JY; Jeung, HW; Kim, DS; Kim, HR; Kim, JH; Kim, MG; Kim, SY; Lee, CU; Lee, GH; Lee, HY; Li, B; Oh, MR; Park, SH; Shin, SJ; So, BO; Sung, MS; Yoo, WH, 2012) |
| " All doses of the extract, its anti-motility fractions and loperamide individually stopped diarrhea within 6-24 h of administration, whilst significantly reducing mucus and fecal fluid content, urine production and intestinal bloating." | 7.78 | Garcinia buchananii bark extract is an effective anti-diarrheal remedy for lactose-induced diarrhea. ( Balemba, OB; Boakye, PA; Brierley, SM; Pasilis, SP, 2012) |
| "Constipation was induced by oral administration of loperamide (3 mg/kg body weight) while the control rats received normal saline." | 7.76 | The effect of Aloe ferox Mill. in the treatment of loperamide-induced constipation in Wistar rats. ( Afolayan, AJ; Sunmonu, TO; Wintola, OA, 2010) |
| " Loperamide, in the dosage used in this study, appears to have no significant effect on the course of acute gastro-enteritis in early childhood." | 6.65 | Loperamide in the treatment of acute gastroenteritis in early childhood. Report of a two centre, double-blind, controlled clinical trial. ( Broadhead, R; Gangal, RN; Hendrickse, RG; Jaswal, OP; Owens, JR, 1981) |
| "Constipation is a risk factor of colorectal cancer." | 5.31 | Decreased colonic mucus in rats with loperamide-induced constipation. ( Hase, T; Meguro, S; Sakata, T; Shimotoyodome, A; Tokimitsu, I, 2000) |
| " bolus of naloxone at a dose of 125 microgram per kilogram of body weight; 48 hours later, each patient received 16 mg of loperamide p." | 5.09 | Hypothalamic-pituitary-adrenal axis sensitivity to opioids in women with polycystic ovary syndrome. ( Barini, A; Ciampelli, M; Cinque, B; Cucinelli, F; Guido, M; Lanzone, A, 2000) |
| "The present study was undertaken to assess SHTC relieved effects on the clinical symptoms of loperamide (LOP) induced constipation in Sprague Dawley (SD) rat model and to clarify the relationship between the protective effect of SHTC on constipation and the gut microbiota." | 4.12 | Chinese patent medicine shouhui tongbian capsule attenuated loperamide-induced constipation through modulating the gut microbiota in rat. ( Erhunmwunsee, F; Li, B; Lin, Q; Liu, M; Mou, Y; Tian, J; Wang, S; Zhang, G, 2022) |
| " platyphylla, alterations in excretion parameters, histological structure, mucin secretion, and related protein levels were investigated in rats with loperamide (Lop)-induced constipation after treatment with aqueous extract of L." | 3.79 | Aqueous extracts of Liriope platyphylla induced significant laxative effects on loperamide-induced constipation of SD rats. ( Hong, JT; Hwang, DY; Kim, JE; Ko, J; Kwak, MH; Lee, YJ, 2013) |
| " Loperamide (2 mg/kg, twice per day) was injected intraperitoneally to induce constipation in the four experimental groups." | 3.78 | Effects of Ficus carica paste on loperamide-induced constipation in rats. ( Back, HI; Chae, HJ; Chae, SW; Ha, KC; Hwang, MH; Im, YJ; Jeon, JY; Jeung, HW; Kim, DS; Kim, HR; Kim, JH; Kim, MG; Kim, SY; Lee, CU; Lee, GH; Lee, HY; Li, B; Oh, MR; Park, SH; Shin, SJ; So, BO; Sung, MS; Yoo, WH, 2012) |
| " All doses of the extract, its anti-motility fractions and loperamide individually stopped diarrhea within 6-24 h of administration, whilst significantly reducing mucus and fecal fluid content, urine production and intestinal bloating." | 3.78 | Garcinia buchananii bark extract is an effective anti-diarrheal remedy for lactose-induced diarrhea. ( Balemba, OB; Boakye, PA; Brierley, SM; Pasilis, SP, 2012) |
| " The present study evaluated the toxicological effect of aqueous leaf extract of the herb at 50, 100 and 200 mg/kg body weight for 7 days on the haematological parameters as well as liver and kidney function indices in loperamide-induced constipated rats." | 3.77 | Toxicological evaluation of aqueous extract of Aloe ferox Mill. in loperamide-induced constipated rats. ( Afolayan, AJ; Sunmonu, TO; Wintola, OA, 2011) |
| "Changes in the parameters of operant feeding behavior and body weight were studied in rats after intragastric administration of μ-opioid receptor agonist loperamide." | 3.77 | Changes in feeding behavior after peripheral loperamide administration in rats. ( Bashkatova, VG; Chumakova, YA; Sudakov, SK, 2011) |
| "Constipation was induced by oral administration of loperamide (3 mg/kg body weight) while the control rats received normal saline." | 3.76 | The effect of Aloe ferox Mill. in the treatment of loperamide-induced constipation in Wistar rats. ( Afolayan, AJ; Sunmonu, TO; Wintola, OA, 2010) |
| " Loperamide, in the dosage used in this study, appears to have no significant effect on the course of acute gastro-enteritis in early childhood." | 2.65 | Loperamide in the treatment of acute gastroenteritis in early childhood. Report of a two centre, double-blind, controlled clinical trial. ( Broadhead, R; Gangal, RN; Hendrickse, RG; Jaswal, OP; Owens, JR, 1981) |
| "Loperamide was also associated with less side effects." | 2.65 | A double-blind crossover study of the effect of loperamide hydrochloride and codeine phosphate on ileostomy output. ( Hill, GL; King, RF; Norton, T, 1982) |
| "Loperamide was more potent in male than female arthritic rats at producing antihyperalgesia." | 1.33 | Nociceptive sensitivity and opioid antinociception and antihyperalgesia in Freund's adjuvant-induced arthritic male and female rats. ( Cook, CD; Nickerson, MD, 2005) |
| "Constipation is a risk factor of colorectal cancer." | 1.31 | Decreased colonic mucus in rats with loperamide-induced constipation. ( Hase, T; Meguro, S; Sakata, T; Shimotoyodome, A; Tokimitsu, I, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (26.32) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 9 (47.37) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, Q | 1 |
| Liu, M | 1 |
| Erhunmwunsee, F | 1 |
| Li, B | 2 |
| Mou, Y | 1 |
| Wang, S | 1 |
| Zhang, G | 1 |
| Tian, J | 1 |
| Eor, JY | 1 |
| Tan, PL | 1 |
| Lim, SM | 1 |
| Choi, DH | 1 |
| Yoon, SM | 1 |
| Yang, SY | 1 |
| Kim, SH | 1 |
| Kim, JE | 2 |
| Park, JW | 1 |
| Kang, MJ | 1 |
| Choi, HJ | 1 |
| Bae, SJ | 1 |
| Choi, Y | 1 |
| Lee, YJ | 2 |
| Seo, S | 1 |
| Hong, JT | 2 |
| Hwang, DY | 2 |
| Kwak, MH | 1 |
| Ko, J | 1 |
| Hsu, SL | 1 |
| Chung, HH | 1 |
| Chen, IH | 1 |
| Tong, YC | 1 |
| Wintola, OA | 2 |
| Sunmonu, TO | 2 |
| Afolayan, AJ | 2 |
| Lee, HY | 1 |
| Kim, JH | 1 |
| Jeung, HW | 1 |
| Lee, CU | 1 |
| Kim, DS | 1 |
| Lee, GH | 1 |
| Sung, MS | 1 |
| Ha, KC | 1 |
| Back, HI | 1 |
| Kim, SY | 1 |
| Park, SH | 1 |
| Oh, MR | 1 |
| Kim, MG | 1 |
| Jeon, JY | 1 |
| Im, YJ | 1 |
| Hwang, MH | 1 |
| So, BO | 1 |
| Shin, SJ | 1 |
| Yoo, WH | 1 |
| Kim, HR | 1 |
| Chae, HJ | 1 |
| Chae, SW | 1 |
| Chumakova, YA | 1 |
| Bashkatova, VG | 1 |
| Sudakov, SK | 1 |
| Boakye, PA | 1 |
| Brierley, SM | 1 |
| Pasilis, SP | 1 |
| Balemba, OB | 1 |
| Cook, CD | 1 |
| Nickerson, MD | 1 |
| Owens, JR | 1 |
| Broadhead, R | 1 |
| Hendrickse, RG | 1 |
| Jaswal, OP | 1 |
| Gangal, RN | 1 |
| Nakamura, H | 1 |
| Ishii, K | 1 |
| Yokoyama, Y | 1 |
| Motoyoshi, S | 1 |
| Suzuki, K | 1 |
| Sekine, Y | 1 |
| Hashimoto, M | 1 |
| Shimizu, M | 1 |
| King, RF | 1 |
| Norton, T | 1 |
| Hill, GL | 1 |
| Puig, MM | 1 |
| Pol, O | 1 |
| Ciampelli, M | 1 |
| Guido, M | 1 |
| Cucinelli, F | 1 |
| Cinque, B | 1 |
| Barini, A | 1 |
| Lanzone, A | 1 |
| Shimotoyodome, A | 1 |
| Meguro, S | 1 |
| Hase, T | 1 |
| Tokimitsu, I | 1 |
| Sakata, T | 1 |
| Awouters, F | 1 |
| Niemegeers, CJ | 1 |
| Kuyps, J | 1 |
| Janssen, PA | 1 |
4 trials available for loperamide and Body Weight
| Article | Year |
|---|---|
Loperamide in the treatment of acute gastroenteritis in early childhood. Report of a two centre, double-blind, controlled clinical trial.
Topics: Body Weight; Child, Preschool; Double-Blind Method; Drug Evaluation; Escherichia coli; Female; Gastr | 1981 |
Loperamide in acute diarrhoea in childhood: results of a double blind, placebo controlled multicentre clinical trial. Diarrhoeal Diseases Study Group (UK).
Topics: Acute Disease; Body Weight; Child, Preschool; Clinical Trials as Topic; Combined Modality Therapy; D | 1984 |
A double-blind crossover study of the effect of loperamide hydrochloride and codeine phosphate on ileostomy output.
Topics: Adult; Aged; Body Weight; Clinical Trials as Topic; Codeine; Diarrhea; Double-Blind Method; Electrol | 1982 |
Hypothalamic-pituitary-adrenal axis sensitivity to opioids in women with polycystic ovary syndrome.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Body Weight; Female; Humans; Hydrocortisone; Hyp | 2000 |
15 other studies available for loperamide and Body Weight
| Article | Year |
|---|---|
Chinese patent medicine shouhui tongbian capsule attenuated loperamide-induced constipation through modulating the gut microbiota in rat.
Topics: Animals; Body Weight; China; Constipation; Gastrointestinal Microbiome; Loperamide; Male; Nonprescri | 2022 |
Laxative effect of probiotic chocolate on loperamide-induced constipation in rats.
Topics: Animals; Body Weight; Chocolate; Claudin-1; Colon; Constipation; Defecation; Faecalibacterium prausn | 2019 |
Laxative Effect of Spicatoside A by Cholinergic Regulation of Enteric Nerve in Loperamide-Induced Constipation: ICR Mice Model.
Topics: Animals; Aquaporins; Body Weight; Cholinergic Agents; Constipation; Disease Models, Animal; Eating; | 2019 |
Aqueous extracts of Liriope platyphylla induced significant laxative effects on loperamide-induced constipation of SD rats.
Topics: Analysis of Variance; Animals; Body Weight; Colon, Transverse; Constipation; Defecation; Laxatives; | 2013 |
Alteration of loperamide-induced prostate relaxation in high-fat diet-fed rats.
Topics: Animals; Blood Pressure; Body Weight; Diet, High-Fat; Feeding Behavior; In Vitro Techniques; Loperam | 2014 |
Toxicological evaluation of aqueous extract of Aloe ferox Mill. in loperamide-induced constipated rats.
Topics: Aloe; Animals; Body Weight; Constipation; Disease Models, Animal; Kidney; Kidney Function Tests; Liv | 2011 |
The effect of Aloe ferox Mill. in the treatment of loperamide-induced constipation in Wistar rats.
Topics: Aloe; Animals; Body Weight; Cathartics; Constipation; Feces; Gastrointestinal Motility; Loperamide; | 2010 |
Effects of Ficus carica paste on loperamide-induced constipation in rats.
Topics: Animals; Antidiarrheals; Body Weight; Constipation; Drinking Behavior; Feces; Feeding Behavior; Gast | 2012 |
Changes in feeding behavior after peripheral loperamide administration in rats.
Topics: Animals; Antidiarrheals; Behavior, Animal; Body Weight; Eating; Feeding Behavior; Loperamide; Male; | 2011 |
Garcinia buchananii bark extract is an effective anti-diarrheal remedy for lactose-induced diarrhea.
Topics: Animals; Antidiarrheals; Body Weight; Cecum; Colon; Diarrhea; Diet; Dietary Sucrose; Drinking; Feces | 2012 |
Nociceptive sensitivity and opioid antinociception and antihyperalgesia in Freund's adjuvant-induced arthritic male and female rats.
Topics: Analgesics, Opioid; Animals; Arthritis, Experimental; Body Weight; Butorphanol; Dose-Response Relati | 2005 |
[Physical dependence on loperamide hydrochloride in mice and rats].
Topics: Administration, Oral; Animals; Antidiarrheals; Behavior, Animal; Body Weight; Dose-Response Relation | 1982 |
Peripheral effects of opioids in a model of chronic intestinal inflammation in mice.
Topics: Animals; Antidiarrheals; Body Weight; Carbon Monoxide; Enteritis; Gastrointestinal Transit; Jejunum; | 1998 |
Decreased colonic mucus in rats with loperamide-induced constipation.
Topics: Animals; Antidiarrheals; Body Weight; Constipation; Feces; Intestinal Mucosa; Loperamide; Male; Mucu | 2000 |
Loperamide antagonism of castor oil-induced diarrhea in rats: a quantitative study.
Topics: Animals; Body Weight; Castor Oil; Diarrhea; Feces; Female; Loperamide; Piperidines; Rats; Time Facto | 1975 |