Page last updated: 2024-10-30

loperamide and Anxiety

loperamide has been researched along with Anxiety in 2 studies

Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.

Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.

Research Excerpts

ExcerptRelevanceReference
" Intragastric administration of loperamide and methylnaloxone reduced animal anxiety evaluated by an increase in the number of entries into and time spent in open arms of the elevated plus-maze."7.76Peripheral administration of loperamide and methylnaloxone decreases the degree of anxiety in rats. ( Bashkatova, VG; Kolpakov, AA; Sudakov, SK; Trigub, MM, 2010)
" Intragastric administration of loperamide and methylnaloxone reduced animal anxiety evaluated by an increase in the number of entries into and time spent in open arms of the elevated plus-maze."3.76Peripheral administration of loperamide and methylnaloxone decreases the degree of anxiety in rats. ( Bashkatova, VG; Kolpakov, AA; Sudakov, SK; Trigub, MM, 2010)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sudakov, SK2
Bashkatova, VG2
Kolpakov, AA2
Trigub, MM1
Chernyaeva, NN1

Other Studies

2 other studies available for loperamide and Anxiety

ArticleYear
Peripheral administration of loperamide and methylnaloxone decreases the degree of anxiety in rats.
    Bulletin of experimental biology and medicine, 2010, Volume: 149, Issue:3

    Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Loperamide; Male; Maze Learning; Naloxone;

2010
Loperamide effects on anxiety level and feeding behavior in rats. Role of vagal afferentation.
    Bulletin of experimental biology and medicine, 2012, Volume: 153, Issue:5

    Topics: Analysis of Variance; Animals; Anxiety; Feeding Behavior; Loperamide; Male; Maze Learning; Rats; Rat

2012