loperamide has been researched along with Addison Disease in 3 studies
Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.
Addison Disease: An adrenal disease characterized by the progressive destruction of the ADRENAL CORTEX, resulting in insufficient production of ALDOSTERONE and HYDROCORTISONE. Clinical symptoms include ANOREXIA; NAUSEA; WEIGHT LOSS; MUSCLE WEAKNESS; and HYPERPIGMENTATION of the SKIN due to increase in circulating levels of ACTH precursor hormone which stimulates MELANOCYTES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of loperamide, an opiate analogue of the piperidine class on pituitary hormone secretion were evaluated in eight patients with Addison's disease." | 9.06 | Loperamide, an opiate analogue, inhibits plasma ACTH levels in patients with Addison's disease. ( Ambrosi, B; Bochicchio, D; Faglia, G, 1986) |
| "The effect of loperamide - a peripheral opiate agonist - on plasma ACTH response to Corticotropin-releasing Hormone (CRH) has been investigated in 6 patients with Addison's disease." | 7.67 | Loperamide modifies but does not block the corticotropin-releasing hormone-induced ACTH response in patients with Addison's disease. ( Ambrosi, B; Bochicchio, D; Colombo, P; Faglia, G; Ferrario, R, 1987) |
| "Loperamide is a peripheral opiate agonist able to inhibit ACTH secretion." | 6.66 | Loperamide, an opiate analog, differently modifies the adrenocorticotropin responses to corticotropin-releasing hormone and lysine vasopressin in patients with Addison's disease. ( Ambrosi, B; Bochicchio, D; Faglia, G, 1988) |
| "The effects of loperamide, an opiate analogue of the piperidine class on pituitary hormone secretion were evaluated in eight patients with Addison's disease." | 5.06 | Loperamide, an opiate analogue, inhibits plasma ACTH levels in patients with Addison's disease. ( Ambrosi, B; Bochicchio, D; Faglia, G, 1986) |
| "The effect of loperamide - a peripheral opiate agonist - on plasma ACTH response to Corticotropin-releasing Hormone (CRH) has been investigated in 6 patients with Addison's disease." | 3.67 | Loperamide modifies but does not block the corticotropin-releasing hormone-induced ACTH response in patients with Addison's disease. ( Ambrosi, B; Bochicchio, D; Colombo, P; Faglia, G; Ferrario, R, 1987) |
| "Loperamide is a peripheral opiate agonist able to inhibit ACTH secretion." | 2.66 | Loperamide, an opiate analog, differently modifies the adrenocorticotropin responses to corticotropin-releasing hormone and lysine vasopressin in patients with Addison's disease. ( Ambrosi, B; Bochicchio, D; Faglia, G, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ambrosi, B | 3 |
| Bochicchio, D | 3 |
| Colombo, P | 1 |
| Ferrario, R | 1 |
| Faglia, G | 3 |
2 trials available for loperamide and Addison Disease
| Article | Year |
|---|---|
Loperamide, an opiate analog, differently modifies the adrenocorticotropin responses to corticotropin-releasing hormone and lysine vasopressin in patients with Addison's disease.
Topics: Addison Disease; Adrenocorticotropic Hormone; Adult; Aged; Corticotropin-Releasing Hormone; Double-B | 1988 |
Loperamide, an opiate analogue, inhibits plasma ACTH levels in patients with Addison's disease.
Topics: Addison Disease; Adrenocorticotropic Hormone; Adult; Aged; beta-Lipotropin; Depression, Chemical; Fe | 1986 |
1 other study available for loperamide and Addison Disease
| Article | Year |
|---|---|
Loperamide modifies but does not block the corticotropin-releasing hormone-induced ACTH response in patients with Addison's disease.
Topics: Addison Disease; Adrenocorticotropic Hormone; Adult; Aged; Corticotropin-Releasing Hormone; Female; | 1987 |