Page last updated: 2024-10-30

loperamide and Acute Disease

loperamide has been researched along with Acute Disease in 49 studies

Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.

Acute Disease: Disease having a short and relatively severe course.

Research Excerpts

ExcerptRelevanceReference
"Recommended treatment for travelers' diarrhea includes the combination of an antibiotic, usually a fluoroquinolone or azithromycin, and loperamide for rapid resolution of symptoms."9.24Trial Evaluating Ambulatory Therapy of Travelers' Diarrhea (TrEAT TD) Study: A Randomized Controlled Trial Comparing 3 Single-Dose Antibiotic Regimens With Loperamide. ( Connor, P; Danboise, B; Fraser, J; Gutierrez, RL; Hulseberg, C; Hutley, EJ; Lalani, T; Porter, CK; Riddle, MS; Simons, MP; Swierczewski, B; Tribble, DR, 2017)
"To compare efficacy and tolerability of a loperamide/simethicone (LOP/SIM) combination product with that of loperamide (LOP) alone, simethicone (SIM) alone, and placebo (PBO) for acute nonspecific diarrhea with gas-related abdominal discomfort."9.12Randomized, double-blind, placebo-controlled clinical trial of loperamide plus simethicone versus loperamide alone and simethicone alone in the treatment of acute diarrhea with gas-related abdominal discomfort. ( Cooper, KM; DuPont, HL; Hanauer, SB; Laudadio, C, 2007)
" Loperamide is an effective anti-diarrheal agent, but it usually induces constipation."9.11A blind, randomized comparison of racecadotril and loperamide for stopping acute diarrhea in adults. ( Liao, KF; Shieh, MJ; Wang, HH, 2005)
"The present study was undertaken to compare the efficacy of a new calmodulin antagonist, zaldaride maleate, with that of placebo or loperamide in persons with traveler's diarrhea."9.08Zaldaride maleate (a new calmodulin antagonist) versus loperamide in the treatment of traveler's diarrhea: randomized, placebo-controlled trial. ( DuPont, HL; Ericsson, CD; Marani, S; Martinez-Sandoval, FG; Okhuysen, PC; Olesen, MA; Ravelli, GP, 1995)
"To explore the optimal dosing regimen for trimethoprim-sulfamethoxazole (TMP-SMX) when used in combination with loperamide to treat traveler's diarrhea, 190 U."9.07Optimal dosing of trimethoprim-sulfamethoxazole when used with loperamide to treat traveler's diarrhea. ( DuPont, HL; Ericsson, CD; Mathewson, JJ; Nicholls-Vasquez, I, 1992)
"An open-label, parallel comparison of loperamide hydrochloride (Imodium A-D) and bismuth subsalicylate (Pepto-Bismol) was conducted using nonprescription dosages in adult students with acute diarrhea (three or more unformed stools in the preceding 24 hours plus at least one additional symptom of enteric infection)."9.06Comparative efficacy of loperamide hydrochloride and bismuth subsalicylate in the management of acute diarrhea. ( Cruz Luna, A; DuPont, HL; DuPont, MW; Ericsson, CD; Flores Sanchez, J; Mathewson, JJ; Mendiola Gomez, J, 1990)
"The efficacy of nonprescription doses of loperamide hydrochloride (Imodium A-D) was compared with nonfibrous activated attapulgite (Diasorb) in a randomized, parallel, open-label study of adult patients with acute diarrhea."9.06A randomized, open-label comparison of nonprescription loperamide and attapulgite in the symptomatic treatment of acute diarrhea. ( Cruz Luna, A; DuPont, HL; DuPont, MW; Ericsson, CD; Mathewson, JJ, 1990)
"Loperamide hydrochloride was compared with bismuth subsalicylate for the treatment of acute nondysenteric travelers' diarrhea in 219 students visiting seven countries in Latin America."9.06Comparison of loperamide with bismuth subsalicylate for the treatment of acute travelers' diarrhea. ( Bitsura, JA; DuPont, HL; Ericsson, CD; Johnson, PC; Morgan, DR; Wood, LV, 1986)
"Loperamide is a safe and effective antidiarrheal for the treatment of acute diarrhea."6.16Safety and efficacy of loperamide. ( Ericsson, CD; Johnson, PC, 1990)
"Recommended treatment for travelers' diarrhea includes the combination of an antibiotic, usually a fluoroquinolone or azithromycin, and loperamide for rapid resolution of symptoms."5.24Trial Evaluating Ambulatory Therapy of Travelers' Diarrhea (TrEAT TD) Study: A Randomized Controlled Trial Comparing 3 Single-Dose Antibiotic Regimens With Loperamide. ( Connor, P; Danboise, B; Fraser, J; Gutierrez, RL; Hulseberg, C; Hutley, EJ; Lalani, T; Porter, CK; Riddle, MS; Simons, MP; Swierczewski, B; Tribble, DR, 2017)
"To compare efficacy and tolerability of a loperamide/simethicone (LOP/SIM) combination product with that of loperamide (LOP) alone, simethicone (SIM) alone, and placebo (PBO) for acute nonspecific diarrhea with gas-related abdominal discomfort."5.12Randomized, double-blind, placebo-controlled clinical trial of loperamide plus simethicone versus loperamide alone and simethicone alone in the treatment of acute diarrhea with gas-related abdominal discomfort. ( Cooper, KM; DuPont, HL; Hanauer, SB; Laudadio, C, 2007)
" Loperamide is an effective anti-diarrheal agent, but it usually induces constipation."5.11A blind, randomized comparison of racecadotril and loperamide for stopping acute diarrhea in adults. ( Liao, KF; Shieh, MJ; Wang, HH, 2005)
"The present study was undertaken to compare the efficacy of a new calmodulin antagonist, zaldaride maleate, with that of placebo or loperamide in persons with traveler's diarrhea."5.08Zaldaride maleate (a new calmodulin antagonist) versus loperamide in the treatment of traveler's diarrhea: randomized, placebo-controlled trial. ( DuPont, HL; Ericsson, CD; Marani, S; Martinez-Sandoval, FG; Okhuysen, PC; Olesen, MA; Ravelli, GP, 1995)
"To explore the optimal dosing regimen for trimethoprim-sulfamethoxazole (TMP-SMX) when used in combination with loperamide to treat traveler's diarrhea, 190 U."5.07Optimal dosing of trimethoprim-sulfamethoxazole when used with loperamide to treat traveler's diarrhea. ( DuPont, HL; Ericsson, CD; Mathewson, JJ; Nicholls-Vasquez, I, 1992)
"An open-label, parallel comparison of loperamide hydrochloride (Imodium A-D) and bismuth subsalicylate (Pepto-Bismol) was conducted using nonprescription dosages in adult students with acute diarrhea (three or more unformed stools in the preceding 24 hours plus at least one additional symptom of enteric infection)."5.06Comparative efficacy of loperamide hydrochloride and bismuth subsalicylate in the management of acute diarrhea. ( Cruz Luna, A; DuPont, HL; DuPont, MW; Ericsson, CD; Flores Sanchez, J; Mathewson, JJ; Mendiola Gomez, J, 1990)
"The efficacy of nonprescription doses of loperamide hydrochloride (Imodium A-D) was compared with nonfibrous activated attapulgite (Diasorb) in a randomized, parallel, open-label study of adult patients with acute diarrhea."5.06A randomized, open-label comparison of nonprescription loperamide and attapulgite in the symptomatic treatment of acute diarrhea. ( Cruz Luna, A; DuPont, HL; DuPont, MW; Ericsson, CD; Mathewson, JJ, 1990)
"Loperamide hydrochloride was compared with bismuth subsalicylate for the treatment of acute nondysenteric travelers' diarrhea in 219 students visiting seven countries in Latin America."5.06Comparison of loperamide with bismuth subsalicylate for the treatment of acute travelers' diarrhea. ( Bitsura, JA; DuPont, HL; Ericsson, CD; Johnson, PC; Morgan, DR; Wood, LV, 1986)
"In this systematic review, we present information relating to the effectiveness and safety of: rotavirus vaccines for the prevention of gastroenteritis; enteral rehydration solutions (oral or gastric), lactose-free feeds, loperamide, probiotics, and zinc for the treatment of gastroenteritis; and ondansetron for the treatment of vomiting."4.87Gastroenteritis in children. ( Dalby-Payne, JR; Elliott, EJ, 2011)
" In acute diarrhoea, loperamide provides more rapid control of symptoms than diphenoxylate when given in a flexible dosage according to unformed bowel movements, and in single dose studies 4mg loperamide has a much longer duration of effect than 5mg diphenoxylate."3.74Loperamide: a review of its pharmacological properties and therapeutic efficacy in diarrhoea. ( Avery, GS; Brogden, RN; Heel, RC; Speight, TM, 1978)
"Racecadotril (acetorphan) is an orally active, potent inhibitor of enkephalinase, which exerts an antihypersecretory effect without increasing intestinal transit time."2.70A multinational comparison of racecadotril and loperamide in the treatment of acute watery diarrhoea in adults. ( Prado, D, 2002)
"The loperamide-treated patients had significantly fewer loose stools during the observation period of 5 days than did the placebo treated patients, median five vs."2.66Symptomatic treatment of acute infectious diarrhoea: loperamide versus placebo in a double-blind trial. ( Alestig, K; Bergström, T; Thorén, K; Trollfors, B, 1986)
"Lidamidine HCl was also shown to be well tolerated; side-effects were generally minor and self-limiting."2.66A multicenter double-blind controlled trial comparing lidamidine HCl and loperamide in the symptomatic treatment of acute diarrhoea. ( Albano, O; Altomare, E; Banterle, C; Chiodo, F; Corazza, GR; Feliciani, M; Fontana, G; Gasbarrini, G; Stufano, N; Valpiani, D, 1986)
"Radiation enteritis is a severe problem in patients receiving irradiation of the abdomen or pelvis in the course of cancer treatment."2.44Medical prevention and treatment of acute and chronic radiation induced enteritis--is there any proven therapy? a short review. ( Böcker, U; Singer, MV; Wenz, F; Zimmerer, T, 2008)
"Oral loperamide is the treatment of choice."2.41Guidelines for adults on self-medication for the treatment of acute diarrhoea. ( Lewis, SJ; Malagelada, JR; Phillips, SF; Speelman, P; Steffen, R; Tytgat, GN; Wingate, D, 2001)
"Diarrhea is the most common health problem of travelers to tropical destinations, affecting up to over 50%, with however considerable regional and seasonal variation."2.41[Travelers' diarrhea]. ( Markwalder, K, 2001)
"Acute infectious diarrhea is a major global health problem."2.41Clinical evaluation and management of acute infectious diarrhea in adults. ( Ilnyckyj, A, 2001)
" We had good results using oral rehydration treatment in combination with loperamide hydrochloride (Immodium) in a colony of rabbits with E."1.27Acute diarrhoeal disease in rabbit: bacteriological diagnosis and efficacy of oral rehydration in combination with loperamide hydrochloride. ( Angulo, AF; Banerjee, AK; Dhasmana, KM; Kong-A-San, J, 1987)
" Diarrhea was controlled with a median dosage of three capsules (6 mg total dose) and a range of two to 12 capsules."1.26The control of acute diarrhea in a large industrial plant. ( Martins, JK; Roedl, G, 1978)

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-199017 (34.69)18.7374
1990's11 (22.45)18.2507
2000's13 (26.53)29.6817
2010's8 (16.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Riddle, MS1
Connor, P1
Fraser, J1
Porter, CK1
Swierczewski, B1
Hutley, EJ1
Danboise, B1
Simons, MP1
Hulseberg, C1
Lalani, T1
Gutierrez, RL1
Tribble, DR1
Linn, YH1
Thu, KK1
Win, NHH1
DuPont, HL9
Labgaa, I1
Uldry, E1
Doerig, C1
Schmidt, S1
Demartines, N1
Halkic, N1
Douma, JA1
Smulders, YM1
Cottrell, J1
Koenig, K1
Perfekt, R1
Hofmann, R1
De Bruyn, G1
Dalby-Payne, JR1
Elliott, EJ1
Müller-Lissner, S1
Prado, D1
Dalby-Payne, J3
Elliott, E3
Kimball, ES1
Palmer, JM1
D'Andrea, MR1
Hornby, PJ1
Wade, PR1
Wang, HH1
Shieh, MJ1
Liao, KF1
Hanauer, SB1
Cooper, KM1
Laudadio, C1
Zimmerer, T1
Böcker, U1
Wenz, F1
Singer, MV1
Roge, J1
Baumer, P1
Berard, H3
Schwartz, JC1
Lecomte, JM3
Okhuysen, PC1
Ericsson, CD6
Marani, S1
Martinez-Sandoval, FG1
Olesen, MA1
Ravelli, GP1
Kaplan, MA1
Prior, MJ1
McKonly, KI1
Temple, AR1
Nelson, EB1
Vetel, JM1
Fretault, N2
Turck, D1
Howaizi, M1
Sbaï-Idrissi, MS1
Baillet, P1
Wingate, D1
Phillips, SF1
Lewis, SJ1
Malagelada, JR1
Speelman, P2
Steffen, R1
Tytgat, GN1
Markwalder, K1
Ilnyckyj, A1
Heap, J1
Jaffé, G1
Heel, RC1
Brogden, RN1
Speight, TM1
Avery, GS1
Martins, JK1
Roedl, G1
Govaerts-Lepicard, M1
Arteaga, I1
Nicholls-Vasquez, I1
Mathewson, JJ3
Lamireau, T1
Fayon, M1
Rigot, A1
Lacombe, D1
Hehunstre, JP1
Sarlangue, J1
Demarquez, JL1
Johnson, PC2
Flores Sanchez, J1
Mendiola Gomez, J1
DuPont, MW2
Cruz Luna, A2
Dzieniszewski, J1
Ciok, J1
Jarosz, M1
van Loon, FP1
Bennish, ML1
Butler, C1
Udvardi, G1
Bergström, T1
Alestig, K1
Thorén, K1
Trollfors, B1
Gasbarrini, G1
Corazza, GR1
Feliciani, M1
Albano, O1
Stufano, N1
Altomare, E1
Fontana, G1
Valpiani, D1
Chiodo, F1
Banterle, C1
Banerjee, AK1
Angulo, AF1
Dhasmana, KM1
Kong-A-San, J1
Du Pont, HL1
Vesikari, T1
Isolauri, E1
Morgan, DR1
Bitsura, JA1
Wood, LV1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Double-Blind, Clinical Trial Evaluating Three Single Dose Regimens With Loperamide for Treatment of Ambulatory Watery Travelers' Diarrhea, and Azithromycin With and Without Loperamide for Treatment of Ambulatory Dysentery/Febrile Diarrhea[NCT01618591]384 participants (Actual)Interventional2012-09-30Terminated (stopped due to AWD arm was completed. ADF diarrhea arm was unable to fill completely and there are no funds remaining to continue recruiting/enrolling.)
Distinct Shifts in the Microbiota Are Associated With Iodine-131 Therapy and Hypothyroidism[NCT03574051]Early Phase 130 participants (Anticipated)Interventional2018-05-01Recruiting
A Randomized, Parallel Group Comparison of Loperamide/Simeticone Caplet, Loperamide/Simeticone Chewable Tablet (IMODIUM® PLUS) and a Probiotic (Saccharomyces Boulardii) in the Treatment of Acute Diarrhea in Adults[NCT00807326]Phase 4415 participants (Actual)Interventional2008-11-30Completed
An Open-label, Randomized, Fasting, Two-period, Single-dose, Crossover Study to Assess Bioequivalence Between a Combination Caplet With Loperamide Hydrochloride and Simethicone (Janssen-Cilag, France), and Imodium® Express Tablets-lyophilizate (Janssen-Ci[NCT04186936]Phase 148 participants (Actual)Interventional2019-12-05Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

14 reviews available for loperamide and Acute Disease

ArticleYear
Acute infectious diarrhea in immunocompetent adults.
    The New England journal of medicine, 2014, Apr-17, Volume: 370, Issue:16

    Topics: Acute Disease; Adult; Anti-Bacterial Agents; Antidiarrheals; Caliciviridae Infections; Diagnosis, Di

2014
[Loperamide for acute infectious diarrhoea].
    Nederlands tijdschrift voor geneeskunde, 2015, Volume: 159

    Topics: Acute Disease; Anti-Bacterial Agents; Antidiarrheals; Communicable Diseases; Diarrhea; Dysentery; Hu

2015
Gastroenteritis in children.
    BMJ clinical evidence, 2011, Jul-26, Volume: 2011

    Topics: Acute Disease; Administration, Oral; Child; Dehydration; Gastroenteritis; Humans; Incidence; Infant;

2011
[Rational approach to the patient with diarrhea].
    MMW Fortschritte der Medizin, 2012, Jun-21, Volume: O 154 Suppl 2

    Topics: Acute Disease; Antidiarrheals; Chronic Disease; Diagnosis, Differential; Diarrhea; Fluid Therapy; Hu

2012
Acute gastroenteritis in children.
    Clinical evidence, 2002, Issue:7

    Topics: Acute Disease; Child; Dehydration; Fluid Therapy; Gastroenteritis; Humans; Loperamide; Randomized Co

2002
Acute gastroenteritis in children.
    Clinical evidence, 2002, Issue:8

    Topics: Acute Disease; Child; Dehydration; Fluid Therapy; Gastroenteritis; Humans; Loperamide

2002
Gastroenteritis in children.
    Clinical evidence, 2003, Issue:10

    Topics: Acute Disease; Antidiarrheals; Child; Fluid Therapy; Gastroenteritis; Humans; Lactose; Loperamide

2003
Medical prevention and treatment of acute and chronic radiation induced enteritis--is there any proven therapy? a short review.
    Zeitschrift fur Gastroenterologie, 2008, Volume: 46, Issue:5

    Topics: Abdominal Neoplasms; Acute Disease; Chronic Disease; Combined Modality Therapy; Controlled Clinical

2008
Guidelines for adults on self-medication for the treatment of acute diarrhoea.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:6

    Topics: Acute Disease; Administration, Oral; Adult; Aged; Aged, 80 and over; Antidiarrheals; Child; Chronic

2001
[Travelers' diarrhea].
    Therapeutische Umschau. Revue therapeutique, 2001, Volume: 58, Issue:6

    Topics: Acute Disease; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Antidiarrheals; Bacterial Infect

2001
Clinical evaluation and management of acute infectious diarrhea in adults.
    Gastroenterology clinics of North America, 2001, Volume: 30, Issue:3

    Topics: Acute Disease; Adult; Antidiarrheals; Cost-Benefit Analysis; Diarrhea; Feces; Fluid Therapy; Humans;

2001
Loperamide: a review of its pharmacological properties and therapeutic efficacy in diarrhoea.
    Drugs, 1978, Volume: 15, Issue:1

    Topics: Acute Disease; Animals; Chronic Disease; Clinical Trials as Topic; Diarrhea; Gastrointestinal Motili

1978
Safety and efficacy of loperamide.
    The American journal of medicine, 1990, Jun-20, Volume: 88, Issue:6A

    Topics: Acute Disease; Clinical Trials as Topic; Diarrhea; Dose-Response Relationship, Drug; Humans; Loperam

1990
Nonfluid therapy and selected chemoprophylaxis of acute diarrhea.
    The American journal of medicine, 1985, Jun-28, Volume: 78, Issue:6B

    Topics: Acute Disease; Adult; Anti-Infective Agents; Bismuth; Campylobacter Infections; Child; Child, Presch

1985

Trials

26 trials available for loperamide and Acute Disease

ArticleYear
Trial Evaluating Ambulatory Therapy of Travelers' Diarrhea (TrEAT TD) Study: A Randomized Controlled Trial Comparing 3 Single-Dose Antibiotic Regimens With Loperamide.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2017, Nov-29, Volume: 65, Issue:12

    Topics: Acute Disease; Adult; Afghanistan; Anti-Bacterial Agents; Azithromycin; Diarrhea; Djibouti; Double-B

2017
Effect of Probiotics for the Prevention of Acute Radiation-Induced Diarrhoea Among Cervical Cancer Patients: a Randomized Double-Blind Placebo-Controlled Study.
    Probiotics and antimicrobial proteins, 2019, Volume: 11, Issue:2

    Topics: Acute Disease; Adult; Diarrhea; Double-Blind Method; Female; Humans; Loperamide; Middle Aged; Probio

2019
Comparison of Two Forms of Loperamide-Simeticone and a Probiotic Yeast (Saccharomyces boulardii) in the Treatment of Acute Diarrhoea in Adults: A Randomised Non-Inferiority Clinical Trial.
    Drugs in R&D, 2015, Volume: 15, Issue:4

    Topics: Acute Disease; Adult; Aged; Diarrhea; Drug Combinations; Female; Humans; Loperamide; Male; Middle Ag

2015
Comparison of Two Forms of Loperamide-Simeticone and a Probiotic Yeast (Saccharomyces boulardii) in the Treatment of Acute Diarrhoea in Adults: A Randomised Non-Inferiority Clinical Trial.
    Drugs in R&D, 2015, Volume: 15, Issue:4

    Topics: Acute Disease; Adult; Aged; Diarrhea; Drug Combinations; Female; Humans; Loperamide; Male; Middle Ag

2015
Comparison of Two Forms of Loperamide-Simeticone and a Probiotic Yeast (Saccharomyces boulardii) in the Treatment of Acute Diarrhoea in Adults: A Randomised Non-Inferiority Clinical Trial.
    Drugs in R&D, 2015, Volume: 15, Issue:4

    Topics: Acute Disease; Adult; Aged; Diarrhea; Drug Combinations; Female; Humans; Loperamide; Male; Middle Ag

2015
Comparison of Two Forms of Loperamide-Simeticone and a Probiotic Yeast (Saccharomyces boulardii) in the Treatment of Acute Diarrhoea in Adults: A Randomised Non-Inferiority Clinical Trial.
    Drugs in R&D, 2015, Volume: 15, Issue:4

    Topics: Acute Disease; Adult; Aged; Diarrhea; Drug Combinations; Female; Humans; Loperamide; Male; Middle Ag

2015
A multinational comparison of racecadotril and loperamide in the treatment of acute watery diarrhoea in adults.
    Scandinavian journal of gastroenterology, 2002, Volume: 37, Issue:6

    Topics: Acute Disease; Administration, Oral; Adult; Antidiarrheals; Diarrhea; Dose-Response Relationship, Dr

2002
A blind, randomized comparison of racecadotril and loperamide for stopping acute diarrhea in adults.
    World journal of gastroenterology, 2005, Mar-14, Volume: 11, Issue:10

    Topics: Acute Disease; Adult; Antidiarrheals; Constipation; Diarrhea; Female; Humans; Loperamide; Male; Midd

2005
Randomized, double-blind, placebo-controlled clinical trial of loperamide plus simethicone versus loperamide alone and simethicone alone in the treatment of acute diarrhea with gas-related abdominal discomfort.
    Current medical research and opinion, 2007, Volume: 23, Issue:5

    Topics: Abdominal Pain; Acute Disease; Adolescent; Adult; Aged; Antidiarrheals; Antifoaming Agents; Diarrhea

2007
Loperamide in acute diarrhoea in childhood: results of a double blind, placebo controlled multicentre clinical trial. Diarrhoeal Diseases Study Group (UK).
    British medical journal (Clinical research ed.), 1984, Nov-10, Volume: 289, Issue:6454

    Topics: Acute Disease; Body Weight; Child, Preschool; Clinical Trials as Topic; Combined Modality Therapy; D

1984
The enkephalinase inhibitor, acetorphan, in acute diarrhoea. A double-blind, controlled clinical trial versus loperamide.
    Scandinavian journal of gastroenterology, 1993, Volume: 28, Issue:4

    Topics: Acute Disease; Adult; Diarrhea; Double-Blind Method; Female; Humans; Loperamide; Male; Neprilysin; T

1993
Zaldaride maleate (a new calmodulin antagonist) versus loperamide in the treatment of traveler's diarrhea: randomized, placebo-controlled trial.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1995, Volume: 21, Issue:2

    Topics: Acute Disease; Adult; Antidiarrheals; Bacteria; Benzimidazoles; Calmodulin; Diarrhea; Double-Blind M

1995
A multicenter randomized controlled trial of a liquid loperamide product versus placebo in the treatment of acute diarrhea in children.
    Clinical pediatrics, 1999, Volume: 38, Issue:10

    Topics: Acute Disease; Child; Child, Preschool; Diarrhea, Infantile; Double-Blind Method; Female; Humans; In

1999
Comparison of racecadotril and loperamide in adults with acute diarrhoea.
    Alimentary pharmacology & therapeutics, 1999, Volume: 13 Suppl 6

    Topics: Acute Disease; Adult; Diarrhea; Double-Blind Method; Female; Humans; Loperamide; Male; Neprilysin; P

1999
Comparison of racecadotril and loperamide in children with acute diarrhoea.
    Alimentary pharmacology & therapeutics, 1999, Volume: 13 Suppl 6

    Topics: Acute Disease; Antidiarrheals; Child; Child, Preschool; Diarrhea; Double-Blind Method; Female; Human

1999
A comparison of lomotil and imodium in acute non-specific diarrhoea.
    The Journal of international medical research, 1977, Volume: 5, Issue:3

    Topics: Acute Disease; Adult; Clinical Trials as Topic; Diarrhea; Diphenoxylate; Female; Humans; Isonipecoti

1977
Loperamide: a review of its pharmacological properties and therapeutic efficacy in diarrhoea.
    Drugs, 1978, Volume: 15, Issue:1

    Topics: Acute Disease; Animals; Chronic Disease; Clinical Trials as Topic; Diarrhea; Gastrointestinal Motili

1978
Multicentre general practice comparison of loperamide and diphenoxylate with atropine in the treatment of acute diarrhoea in adults.
    The British journal of clinical practice, 1979, Volume: 33, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Atropine; Diarrhea; Diphenoxylate; Drug Therapy, Combination; Huma

1979
Optimal dosing of trimethoprim-sulfamethoxazole when used with loperamide to treat traveler's diarrhea.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:12

    Topics: Acute Disease; Adult; Diarrhea; Double-Blind Method; Drug Administration Schedule; Drug Interactions

1992
Safety and efficacy of loperamide.
    The American journal of medicine, 1990, Jun-20, Volume: 88, Issue:6A

    Topics: Acute Disease; Clinical Trials as Topic; Diarrhea; Dose-Response Relationship, Drug; Humans; Loperam

1990
Comparative efficacy of loperamide hydrochloride and bismuth subsalicylate in the management of acute diarrhea.
    The American journal of medicine, 1990, Jun-20, Volume: 88, Issue:6A

    Topics: Acute Disease; Adult; Bismuth; Clinical Trials as Topic; Diarrhea; Dose-Response Relationship, Drug;

1990
A randomized, open-label comparison of nonprescription loperamide and attapulgite in the symptomatic treatment of acute diarrhea.
    The American journal of medicine, 1990, Jun-20, Volume: 88, Issue:6A

    Topics: Acute Disease; Adult; Diarrhea; Dose-Response Relationship, Drug; Female; Humans; Loperamide; Magnes

1990
Loperamide (imodium)--clinical trial.
    Therapia Hungarica (English edition), 1990, Volume: 38, Issue:2

    Topics: Acute Disease; Chronic Disease; Clinical Trials as Topic; Diarrhea; Humans; Loperamide; Piperidines

1990
Double blind trial of loperamide for treating acute watery diarrhoea in expatriates in Bangladesh.
    Gut, 1989, Volume: 30, Issue:4

    Topics: Acute Disease; Adult; Aged; Bangladesh; Clinical Trials as Topic; Diarrhea; Double-Blind Method; Eur

1989
Symptomatic treatment of acute infectious diarrhoea: loperamide versus placebo in a double-blind trial.
    The Journal of infection, 1986, Volume: 12, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Bacterial Infections; Clinical Trials as Topic; Diarrhea; Do

1986
A multicenter double-blind controlled trial comparing lidamidine HCl and loperamide in the symptomatic treatment of acute diarrhoea.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:12

    Topics: Acute Disease; Antidiarrheals; Clinical Trials as Topic; Diarrhea; Double-Blind Method; Female; Huma

1986
Nonfluid therapy and selected chemoprophylaxis of acute diarrhea.
    The American journal of medicine, 1985, Jun-28, Volume: 78, Issue:6B

    Topics: Acute Disease; Adult; Anti-Infective Agents; Bismuth; Campylobacter Infections; Child; Child, Presch

1985
A comparative trial of cholestyramine and loperamide for acute diarrhoea in infants treated as outpatients.
    Acta paediatrica Scandinavica, 1985, Volume: 74, Issue:5

    Topics: Acute Disease; Ambulatory Care; Child, Preschool; Cholestyramine Resin; Clinical Trials as Topic; Di

1985
Comparison of loperamide with bismuth subsalicylate for the treatment of acute travelers' diarrhea.
    JAMA, 1986, Feb-14, Volume: 255, Issue:6

    Topics: Acute Disease; Adult; Antidiarrheals; Bismuth; Diarrhea; Humans; Latin America; Loperamide; Organome

1986

Other Studies

12 other studies available for loperamide and Acute Disease

ArticleYear
Loperamide-induced recurrent acute pancreatitis.
    Clinics and research in hepatology and gastroenterology, 2016, Volume: 40, Issue:1

    Topics: Acute Disease; Aged; Antidiarrheals; Female; Humans; Loperamide; Pancreatitis; Recurrence

2016
Diarrhea in adults (acute).
    American family physician, 2008, Aug-15, Volume: 78, Issue:4

    Topics: Acute Disease; Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Antidiarrheals; Combined Modality Th

2008
Acute colitis induction by oil of mustard results in later development of an IBS-like accelerated upper GI transit in mice.
    American journal of physiology. Gastrointestinal and liver physiology, 2005, Volume: 288, Issue:6

    Topics: Acute Disease; Animals; Antidiarrheals; Colitis; Colon; Diarrhea; Disease Models, Animal; Gastrointe

2005
[Loperamide-induced acute pancreatitis].
    Gastroenterologie clinique et biologique, 2000, Volume: 24, Issue:5

    Topics: Acute Disease; Antidiarrheals; Female; Humans; Loperamide; Middle Aged; Pancreatitis

2000
Loperamide and acute infective diarrhoea in children.
    Lancet (London, England), 1979, Dec-15, Volume: 2, Issue:8155

    Topics: Acute Disease; Child; Child, Preschool; Diarrhea; Diphenoxylate; Dysentery, Bacillary; Humans; Infan

1979
The control of acute diarrhea in a large industrial plant.
    Journal of occupational medicine. : official publication of the Industrial Medical Association, 1978, Volume: 20, Issue:4

    Topics: Absenteeism; Acute Disease; Adult; Automobiles; Diarrhea; Female; Humans; Loperamide; Male; Occupati

1978
[Seriousness factors in acute poisoning].
    Bruxelles medical, 1978, Issue:12

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Belgium; Child; Child, Preschool; Chloroquine; Colchi

1978
[Loperamide in acute diarrhea (author's transl)].
    Revista medica de Chile, 1977, Volume: 105, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Aged; Diarrhea; Drug Evaluation; Female; Humans; Loperamide; Male;

1977
[Loperamide and acute diarrhea in infants].
    Archives francaises de pediatrie, 1991, Volume: 48, Issue:9

    Topics: Acute Disease; Diarrhea, Infantile; Female; Humans; Infant; Intestinal Obstruction; Loperamide

1991
Subacute diarrhea. To treat or to wait?
    Hospital practice (Office ed.), 1989, Mar-30, Volume: 24, Issue:3A

    Topics: Acute Disease; Adult; Diagnosis, Differential; Diarrhea; Enterobacteriaceae Infections; Female; Huma

1989
Examination of Imodium in patients suffering from acute and chronic diarrhoea.
    Therapia Hungarica (English edition), 1986, Volume: 34, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Chronic Disease; Diarrhea; Female; Humans; Loperamide; Male;

1986
Acute diarrhoeal disease in rabbit: bacteriological diagnosis and efficacy of oral rehydration in combination with loperamide hydrochloride.
    Laboratory animals, 1987, Volume: 21, Issue:4

    Topics: Acute Disease; Animals; Combined Modality Therapy; Diarrhea; Fluid Therapy; Loperamide; Piperidines;

1987