loperamide has been researched along with Abdominal Pain in 9 studies
Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.
Abdominal Pain: Sensation of discomfort, distress, or agony in the abdominal region.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our aim was to compare the efficacy and tolerability of loperamide and racecadotril in elderly patients with acute diarrhea." | 9.14 | Prospective randomized double-blind trial of racecadotril compared with loperamide in elderly people with gastroenteritis living in nursing homes. ( Colosimo, M; Cucchiara, S; Curto, LS; De Sarro, G; Falcone, D; Gallelli, L; Luberto, L; Marigliano, NM; Mazzei, F; Rende, P; Tolotta, GA, 2010) |
| "To compare efficacy and tolerability of a loperamide/simethicone (LOP/SIM) combination product with that of loperamide (LOP) alone, simethicone (SIM) alone, and placebo (PBO) for acute nonspecific diarrhea with gas-related abdominal discomfort." | 9.12 | Randomized, double-blind, placebo-controlled clinical trial of loperamide plus simethicone versus loperamide alone and simethicone alone in the treatment of acute diarrhea with gas-related abdominal discomfort. ( Cooper, KM; DuPont, HL; Hanauer, SB; Laudadio, C, 2007) |
| "Irritable bowel syndrome with diarrhea (IBS-D) is often managed with over-the-counter therapies such as loperamide, though with limited success." | 5.24 | Eluxadoline Efficacy in IBS-D Patients Who Report Prior Loperamide Use. ( Cash, BD; Chey, WD; Covington, PS; Dove, LS; Lacy, BE; Lembo, AJ, 2017) |
| "Our aim was to compare the efficacy and tolerability of loperamide and racecadotril in elderly patients with acute diarrhea." | 5.14 | Prospective randomized double-blind trial of racecadotril compared with loperamide in elderly people with gastroenteritis living in nursing homes. ( Colosimo, M; Cucchiara, S; Curto, LS; De Sarro, G; Falcone, D; Gallelli, L; Luberto, L; Marigliano, NM; Mazzei, F; Rende, P; Tolotta, GA, 2010) |
| "To compare efficacy and tolerability of a loperamide/simethicone (LOP/SIM) combination product with that of loperamide (LOP) alone, simethicone (SIM) alone, and placebo (PBO) for acute nonspecific diarrhea with gas-related abdominal discomfort." | 5.12 | Randomized, double-blind, placebo-controlled clinical trial of loperamide plus simethicone versus loperamide alone and simethicone alone in the treatment of acute diarrhea with gas-related abdominal discomfort. ( Cooper, KM; DuPont, HL; Hanauer, SB; Laudadio, C, 2007) |
| "Constipation is a major gastrointestinal motility disorder with clinical need for effective drugs." | 1.40 | Effects of novel TRPA1 receptor agonist ASP7663 in models of drug-induced constipation and visceral pain. ( Doihara, H; Itou, H; Kaku, H; Keto, Y; Kojima, R; Nozawa, K; Yokoyama, T, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lacy, BE | 1 |
| Chey, WD | 1 |
| Cash, BD | 1 |
| Lembo, AJ | 1 |
| Dove, LS | 1 |
| Covington, PS | 1 |
| Kojima, R | 1 |
| Nozawa, K | 1 |
| Doihara, H | 1 |
| Keto, Y | 1 |
| Kaku, H | 1 |
| Yokoyama, T | 1 |
| Itou, H | 1 |
| Talley, NJ | 1 |
| Gallelli, L | 1 |
| Colosimo, M | 1 |
| Tolotta, GA | 1 |
| Falcone, D | 1 |
| Luberto, L | 1 |
| Curto, LS | 1 |
| Rende, P | 1 |
| Mazzei, F | 1 |
| Marigliano, NM | 1 |
| De Sarro, G | 1 |
| Cucchiara, S | 1 |
| Lee, HM | 1 |
| Villa, AF | 1 |
| Caudrelier, S | 1 |
| Garnier, R | 1 |
| Tan, SL | 1 |
| Huang, WS | 1 |
| Lin, JW | 1 |
| Frenz, MB | 1 |
| Dunckley, P | 1 |
| Camporota, L | 1 |
| Jewell, DP | 1 |
| Travis, SP | 1 |
| Mearin, F | 1 |
| Hanauer, SB | 1 |
| DuPont, HL | 1 |
| Cooper, KM | 1 |
| Laudadio, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Open-label, Randomized, Fasting, Two-period, Single-dose, Crossover Study to Assess Bioequivalence Between a Combination Caplet With Loperamide Hydrochloride and Simethicone (Janssen-Cilag, France), and Imodium® Express Tablets-lyophilizate (Janssen-Ci[NCT04186936] | Phase 1 | 48 participants (Actual) | Interventional | 2019-12-05 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for loperamide and Abdominal Pain
| Article | Year |
|---|---|
Can loperamide cause acute pancreatitis?
Topics: Abdominal Pain; Adolescent; Amylases; Antidiarrheals; Drug Overdose; Female; Humans; Lipase; Loperam | 2011 |
Watermelon colon: case report and review.
Topics: Abdominal Pain; Acrylic Resins; Aged; Biopsy, Needle; Cecum; Colonic Diseases; Colonoscopy; Drug The | 2003 |
[Drug treatment of irritable bowel syndrome: an unmet need].
Topics: Abdominal Pain; Analgesics; Antidepressive Agents, Tricyclic; Antidiarrheals; Carbolines; Controlled | 2007 |
3 trials available for loperamide and Abdominal Pain
| Article | Year |
|---|---|
Eluxadoline Efficacy in IBS-D Patients Who Report Prior Loperamide Use.
Topics: Abdominal Pain; Adult; Antidiarrheals; Diarrhea; Double-Blind Method; Female; Gastrointestinal Agent | 2017 |
Prospective randomized double-blind trial of racecadotril compared with loperamide in elderly people with gastroenteritis living in nursing homes.
Topics: Abdominal Pain; Aged; Aged, 80 and over; Aging; Antidiarrheals; Cytochrome P-450 Enzyme System; Dehy | 2010 |
Randomized, double-blind, placebo-controlled clinical trial of loperamide plus simethicone versus loperamide alone and simethicone alone in the treatment of acute diarrhea with gas-related abdominal discomfort.
Topics: Abdominal Pain; Acute Disease; Adolescent; Adult; Aged; Antidiarrheals; Antifoaming Agents; Diarrhea | 2007 |
3 other studies available for loperamide and Abdominal Pain
| Article | Year |
|---|---|
Effects of novel TRPA1 receptor agonist ASP7663 in models of drug-induced constipation and visceral pain.
Topics: Abdominal Pain; Analgesics; Animals; Calcium; Calcium Channels; Clonidine; Colon; Constipation; Gast | 2014 |
Board Review Vignette: Irritable Bowel Syndrome.
Topics: Abdominal Pain; Adult; Anion Exchange Resins; Antidiarrheals; Carbolines; Cholestyramine Resin; Cons | 2016 |
Comparison between prospective and retrospective evaluation of Crohn's disease activity index.
Topics: Abdominal Pain; Antidiarrheals; Colonic Diseases; Crohn Disease; Diphenoxylate; Feces; Health Status | 2005 |