lonomycin has been researched along with Toxoplasmosis* in 1 studies
1 other study(ies) available for lonomycin and Toxoplasmosis
| Article | Year |
|---|---|
An in vitro study on the toxoplasmacidal activity of lonomycin A in host cells.
Lonomycin A at various concentrations was tested for its inhibitory effect on Toxoplasma multiplication in host cells cultured in vitro. Results indicate that lonomycin A at a concentration of 0.01 micrograms per ml in TC-199 medium demonstrated a high degree of antitoxoplasma activity with complete inhibition of Toxoplasma multiplication in the host cells. Lymphokines, a supernatant produced from spleen cells of mice infected chronically with Toxoplasma gondii, inhibited Toxoplasma multiplication in mice macrophage and kidney cell monolayers. However, lonomycin A inhibited completely Toxoplasma multiplication in non-specific cells, i.e. not only in mice macrophages and kidney cells but also in cells of human and other animal species. Topics: Animals; Anti-Bacterial Agents; Antiprotozoal Agents; Cats; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Kidney; Lymphokines; Macrophages; Nigericin; Swine; Toxoplasma; Toxoplasmosis | 1981 |